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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

  • The Kinin System

    • 1st Edition
    • Stephen G. Farmer
    • English
    Bradykinin is a type of plasma hormone that causes blood vessels to dilate, resulting in a drop in blood pressure, the contraction of muscles in the lungs, intestines, and uterus, and pain. The Kinin System reviews the molecular biology of the kinins through their roles in a complex array of inflammatory conditions such as asthma, GI disease, cardiovascular complaints and examines the future therapeutic opportunities. From the prepublication reviews:"A delicious masterpiece."--Chef'... DigestThe Kinin System is a comprehensive, timely book covering all aspects of the kinin system from its disocvery to the pathophysiology, pharmacology, and molecular biology of the mechanisms regulating kinin production to kinin receptors in health and disease. The authors take a refreshingly different view of the kinin system than previous books on the subject. Several chapters contain new information on the gene expression, regulation, and cell surface presentation of kininogens and kallikreins, as well as new data, some of it from human studies, on the role of kinins in pain angiogenesis, tissue repair, sepsis, arthritis, asthma, allergic rhinits, myocardial ischemia, and other diseases.

  • The Eye's Aqueous Humor: From Secretion to Glaucoma

    • 1st Edition
    • Volume 45
    • English
    This volume presents a basic consensus of how the aqueous humor is formed and exits through the trabecular meshwork and canal of Schlemm. It presents a timely update to current knowledge of the molecular transport mechanisms which underlie aqueous humor dynamics. In addition, it provides a concise description of the clinical approaches used for assessing these basic transport processes. The book emphasizes the phenomenon of the diurnal rhythm of aqueous humor formation, from both the clinical and molecular points of view. This phenomenon provides the major indication that aqueous humor secretion is regulated.

  • Side Effects of Drugs Annual

    • 1st Edition
    • Volume 19
    • English
    The very latest information on adverse drug effects from the international literature, compiled by an international team of experts.New reports are presented of adverse drug effects, critically analysed in context, in terms of clinical relevance and importance, and cross-referring to previous reports where necessary. New adverse effects are reported and evaluated, and previously reported adverse effects are re-evaluated in the light of the most recent information.Unique features:Reviews in which selected adverse effects are discussed in depth.Two separate indexes enhance the use of the book, allowing the reader to access information by drug name or by, adverse effects.

  • Antioxidants in Disease Mechanisms and Therapy

    • 1st Edition
    • Volume 38
    • English
    Antioxidants in Disease Mechanisms and Therapy presents molecular actions of natural and synthetic antioxidants and emphasizes the potential role in disease mechanisms and therapeutic strategies. The modulationof gene expression by the induction of antioxidant enzymes is a novel role beyond the direct antioxidant action. The volume explores the current state of knowledge on oxidants and antioxidants in disease processes, including arteriosclerosis, adult respiratory distress syndrome, cystic fibrosis, Down's syndrome, inflammation, cataract, age-related macular degeneration, afflications of the nervous system, AIDS, liver diseases, diabetes, skin diseases, and cancer.

  • International Review of Neurobiology

    • 1st Edition
    • Volume 39
    • English
    Since 1959, International Review of Neurobiology has been a well known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. This important serial is now being combined with Neuroscience Perspectives and Methods in Neurosciences. This combination results in a series that reaches a wider audience and publishes a greater number of thematic volumes.

  • Drugs and Human Lactation

    A Comprehensive Guide to the Content and Consequences of Drugs, Micronutrients, Radiopharmaceuticals and Environmental and Occupational Chemicals in Human Milk
    • 2nd Edition
    • A. Astrup-Jensen + 12 more
    • P.N. Bennett
    • English
    Now in its second edition, Drugs and Human Lactation is a comprehensive guide to the content and consequences of xenobiotics and micronutrients in human milk, and remains by far the most thorough and extensive work available on this subject. The excellent methodology used for the compilation of the 1st edition has been retained.It begins with an outline of the processes by which substances enter milk during its formation, the effects of drugs on the milk production process, the main determinants of drug excretion into milk and their disposition in the child. There follows an analysis of current data on 234 individual drugs, describing the extent of their passage into human milk, and assessing the risk to the suckling infant. Vitamins and essential trace elements, and radiopharmaceuticals are similarly reviewed. Also included is an account of the factors that influence the passage of environmental and occupational chemicals into milk. The result is a complete overview of what is known and proven, with clear pointers to matters which require further study, and brings the various subject areas up to date. Risks, uncertainties and false alarms which exist have been defined in such a way that they can be avoided.Once again, Drugs and Human Lactation provides a comprehensive guide to the content and consequences of substances in milk. The volume will provide a rational basis for making therapeutic decisions in women who seek to breast-feed.Reproduc... Immunology on the first edition: ...a superbly written compendium of reliable information and sensible conclusions and recommendations.

  • In Vitro Methods in Pharmaceutical Research

    • 1st Edition
    • Jose V. Castell + 1 more
    • English
    In Vitro Methods in Pharmaceutical Research provides a comprehensive guide to laboratory techniques for evaluating in vitro organ toxicity using cellular models. Step-by-step practical tips on how to perform and interpret assays for drug metabolism and toxicity assessment are provided, along with a comparison of different techniques available. It is a welcome addition to the literature at a time when interest is growing in cellular in vitro models for toxicology and pharmacology studies.

  • Advances in Pharmacology

    • 1st Edition
    • Volume 37
    • English
    Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental.

  • Intracellular Signal Transduction

    • 1st Edition
    • Volume 36
    • English
    Signal transduction is one of the most rapidly expanding fields in biomedical research. Written by renowned experts, Intracellular Signal Transduction provides up-to-date reviews on the role of protein phosphorylation cascades, and the structure, regulation, and function of protein kinases and phosphatases. This volume was compiled in honor of Dr. Edwin Krebs' pioneering work in the field of signal transduction which earned him a Nobel Prize. It providesinformation in a variety of areas relating to the biochemistry, cell biology, and pharmacology of the signal transduction process in eukaryotic cells.

  • Phosphodiesterase Inhibitors

    • 1st Edition
    • English
    Non-selective inhibitors of cyclic nucleotide phosphodiesterase (PDE), such as theophylline, have been used extensively since 1958. In the decade of the '70s, various PDE isoenzymes were defined which led to the development of the second generation of PDE inhibitors. Currently a variety of these new inhibitors are under test as potential anti-inflammatory drugs. During the past five years, molecular biology has revealed a superfamily of these phosphodiesterase isoenzymes. This book summarizes the present state of knowledge, as well as giving a comprehensive description of the compounds available. It will be invaluable for everyone who wants to choose the most suitable PDE inhibitor for their research or who is dealing with such drugs in a clinical setting.

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