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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

  • Advances in Pharmacology

    • 1st Edition
    • Volume 22
    • English

  • Cytochrome P450

    Protein-Dna Interactions
    • 1st Edition
    • Volume 206
    • John N. Abelson + 1 more
    • English
    This volume represents the first collection of methodological approaches to P450 investigation which includes the use of molecular biological techniques. It is designed for use by those who study the P450 super family. Methods are presented for the identification and characterization of unique forms of P450 mRNA and protein, for expression of P450s in heterologous systems, for the study of human P450s, and for the characterization of P450s in different tissues.

  • Drug Resistance As a Biochemical Target in Cancer Chemotherapy

    • 1st Edition
    • Makoto Ogawa
    • English
    Drug Resistance as a Biochemical Target in Cancer Chemotherapy covers the proceedings of the 13th Bristol-Myers Squibb Symposium on Cancer Research, entitled ""Drug Resistance as a Biochemical Target in Cancer Chemotherapy"", hosted by the Japanese Foundation for Cancer Research in Tokyo. This book is divided into four parts encompassing 18 chapters that summarize the results of both preclinical and clinical research on circumvention of drug resistance. The first two parts discuss the genetic aspects of multidrug resistance and the proteins involved in drug resistance. These parts also examine the structure, function, and expression of P-glycoproteins, with an emphasis on the role of these proteins as targets for cancer chemotherapy. The third part describes the methods for detection of P-glycoprotein and its antagonists to counter clinical drug resistance. This topic is followed by a discussion on the interactions among steroid hormones, steroid hormone receptors, antiandrogens, biological-response modifiers, and cytotoxic drugs in human breast cancer. The concluding part explores the clinical applications of chemosensitizers in cancer therapy. This part also considers the alternative clinical approaches against drug failure, including non-crosss-resistant therapies, autologous bone marrow transplantation, dose-intensive therapy, and high-dose chemotherapy. Biomedical scientists and researchers and clinicians will find this book invaluable.

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 26
    • English

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 41
    • English

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 40
    • English

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 28
    • English
    The six reviews in this volume cover once again a most comprehensive range of topics. The anti-malarial activity of the 8-aminoquinolines is examined, with an eye to the development of a single, broad-spectrum drug. Chelation, important in removal of toxic metals from the body, is reviewed for tripositive elements. A new and promising approach to total parenteral nutrition is described. Our indebtedness to the plant origins of many modern drugs is noted in the context of new chemicals. Heterosteroids and receptor-specific opioid peptides constitute two further topics, each case highlighting the wide range of relevant biologically active compounds. Yet another volume challenging the staggering diversity of the field of medicinal chemistry.

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 39
    • English

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 25
    • English

  • Advances in Pharmacology

    • 1st Edition
    • Volume 21
    • English

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