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Elsevier

Books in Life sciences

  • Plant-Based Drug Discovery

    Unveiling Molecular Targets for Metabolic Conditions
    • 1st Edition
    • Mamta Bisht + 2 more
    • English
    Plant-Based Drug Discovery: Unveiling Molecular Targets for Metabolic Conditions provides an in-depth examination of the molecular mechanisms of phytochemicals and their potential in treating metabolic diseases. This comprehensive guide begins with an introduction to the prevalence and impact of metabolic disorders, emphasizing the significant role of phytochemicals in their management. The book delves into scientific concepts and research findings, offering valuable insights for researchers and healthcare professionals in the fields of molecular biology, biochemistry, pharmacology, and biotechnology. Chapters cover various crucial topics such as oxidative stress, epigenetic mechanisms, and mitophagy.In addition, they explore the targeting of molecular chaperones and the molecular targets of plant nutraceuticals for treating obesity, cardiovascular disease, and type 2 diabetes. The book also addresses technological advances, including AI and nanotechnology, highlighting opportunities and challenges in improving the use of plant molecules for metabolic disorder treatments. It serves as an essential resource for those engaged in drug discovery and related areas.

  • Biliary Tract Neoplasms

    • 1st Edition
    • Timothy M. Pawlik + 1 more
    • English
    Biliary Tract Neoplasms is a state-of-art reference of the multimodality management of bile duct cancer written by leaders in the field. As targeted therapy and clinical trials in this field are exploding, and the incidence of the disease is increasing, now is the time to address the topic in practical manner. This reference addresses surgical approaches to biliary neoplasms, targeted personalized systemic approaches to biliary neoplasms, and other treatment modalities such as radiotherapy and ablation. It is intended for scientists, researchers, clinicians, practicing surgeons, surgical oncologists, transplant surgeons as well as fellows/residents in the surgical space.The book's translational nature and impact of basic science findings that have informed targeted therapy for biliary neoplasms provide the very latest data on surgery, medical, imaging, and multi-modality care of biliary neoplasm to educate and inform care of this patient population.

  • Phytoceuticals in Food for Health and Wellness

    Harnessing Plant Therapeutics
    • 1st Edition
    • Tanmay Sarkar + 2 more
    • English
    Phytoceuticals in Food for Health and Wellness: Harnessing Plant Therapeutics emphasizes the growing interest in the potential health benefits of phytochemicals in wellness and product development by uncovering innate bioactive compounds found in plants. Highlighting the diverse classes of phytochemicals, including flavonoids, carotenoids, polyphenols, antioxidants, and alkaloids, this book explores the sources, chemical structures, and distribution in various plants and what role they play in nutrition and disease prevention. Phytoceutical and phytochemical approaches targeting immunity, obesity, cancer, respiratory, gut, cardiovascular, and eye health, and more, will be discussed. Through traditional and modern extraction methods, Phytoceuticals in Food for Health and Wellness: Harnessing Plant Therapeutics also demonstrates how plant bioactives can be used for fortifying foods for optimal nutrition, innovating in product development, and developing the use of phytochemicals in culinary and food manufacturing applications to maximize favor and extend shelf-life.

  • Handbook of Intervention Science

    From Design to Implementation
    • 1st Edition
    • Laura N.Gitlin + 1 more
    • English
    Handbook of Intervention Science: From Design to Implementation discusses multiple approaches for developing and advancing interventions at the individual, family, community, health system, and policy level. The book focuses on creating interventions suitable for diverse populations from racial, ethnical, geographical, and socioeconomical perspectives. Combining best practices with a practical approach, the book enables readers to advance their intervention research. It covers intervention design, data capture in trials, and evaluation. Decision trees help illustrate when to move forward with an implementation relative to the need for further work.

  • Less-Supervised Segmentation with CNNs

    Scenarios, Models and Optimization
    • 1st Edition
    • Jose Dolz + 2 more
    • English
    Less-Supervised Segmentation with CNNs: Scenarios, Models and Optimization reviews recent progress in deep learning for image segmentation under scenarios with limited supervision, with a focus on medical imaging. The book presents main approaches and state-of-the-art models and includes a broad array of applications in medical image segmentation, including healthcare, oncology, cardiology and neuroimaging. A key objective is to make this mathematical subject accessible to a broad engineering and computing audience by using a large number of intuitive graphical illustrations. The emphasis is on giving conceptual understanding of the methods to foster easier learning.This book is highly suitable for researchers and graduate students in computer vision, machine learning and medical imaging.

  • Biosensing the Future

    Wearable, Ingestible and Implantable Technologies for Health and Wellness Monitoring Part B
    • 1st Edition
    • Volume 216
    • English
    Biosensing the Future: Wearable, Ingestible and Implantable Technologies for Health and Wellness Monitoring, Part B, Volume 216 covers the rapidly evolving field of biosensors, highlighting their transformative role in modern healthcare, disease monitoring, and personalized medicine. Chapters in this new release include Technologies and emerging trends in wearable biosensing, Implantable biosensors: advancements and applications, Neural implants: restoring function and enhancing quality of life, Ingestible biosensors: monitoring health from within, Ingestible biosensors for monitoring digestive health and nutritional monitoring, Ingestible biosensors for drug delivery monitoring, Artificial intelligence in wearable biosensing: enhancing data analysis and decision-making, and much more.Additional sections cover Wearable Privacy, Ethical and regulatory landscape of wearable, ingestible, and implantable technologies, Characterization of skeletal muscle contraction using a flexible and wearable ultrasonic sensor, Wearable Biosensors for Climate Change and Health Research, and much more. The book systematically explores the integration of biosensing technologies into wearable, ingestible, and implantable devices, offering a multidimensional perspective on their applications, advancements, and future directions.

  • Methodology in Radiomics

    Step-by-step Guide in Radiomics Pipeline
    • 1st Edition
    • Salvatore Claudio Fanni + 3 more
    • English
    Methodology in Radiomics: Step-by-step Guide in Radiomics Pipeline is an essential resource for anyone interested in the rapidly evolving field of radiomics. This comprehensive guide delves into the history and fundamental principles of radiomics, providing readers with a clear understanding of how to implement each step in the radiomic pipeline. The book is designed to bridge the gap between radiomics research and clinical practice, making it an invaluable reference for imaging scientists, researchers, and medical professionals. The book not only covers the basics but also includes troubleshooting techniques to overcome common challenges.It discusses current research and future directions, offering insights into the potential of radiomics in clinical settings. This guide ensures that readers are well-equipped to navigate the complexities of radiomics, fostering a deeper understanding of its applications and advances in medical imaging.

  • Nanomedicine Advancements and Intersectional Perspectives for Women's Health

    • 1st Edition
    • Pankaj Sharma + 1 more
    • English
    Nanomedicine Advancements and Intersectional Perspectives for Women's Health provides detailed insights and innovative treatments that specifically address health issues that women face. It provides valuable information and practical solutions based on scientific evidence providing comprehensive information about nanomedicine advancements specifically targeted towards improving health outcomes. It offers clear explanations of complex medical concepts in nanomedicine in a reader-friendly manner to help bridge the knowledge gap on this topic. By providing clear explanations, real-life examples, and practical insights, it empowers readers with valuable information that can help healthcare professionals make informed decisions working in relevant fields as well as researchers new to the field.

  • Pharmacological Targets in Metabolic Diseases

    Challenges and Opportunities
    • 1st Edition
    • Marcos Roberto de Oliveira
    • English
    Pharmacological Targets in Metabolic Diseases: Challenges and Opportunities is a complete reference on possible drug development targets to be leveraged in therapeutic developments. Covering both signaling pathways and specific proteins, the book presents ways to modulate the molecular and cellular alterations observed in metabolic diseases and disorders through the application of new or classical drugs. The comprehensive coverage starts by providing an overview of metabolic diseases and disorders, biological alterations, and pharmacological targets. This section covers targets at both molecular, and subcellular and cellular levels. The next section in the book is focused on pharmaceutical targeting of organs, including a dedicated chapter to the gut-brain axis. Next comes a thorough review of the current advances in metabolic syndrome research. Section VI is focused on inborn errors of metabolism and is followed by a section devoted to natural molecules and their pharmacological potential to treat these conditions. The Editor introduces next a whole section dedicated to the role of the microbiota in metabolic diseases therapeutics. The following sections cover the impact of aging, nanotechnology, the environment, and finally diagnostic techniques in metabolic diseases and disorders. Pharmacological Targets in Metabolic Diseases: Challenges and Opportunities meet the needs of pharmacology researchers looking for a comprehensive and authoritative source of information on possible therapeutic targets to treat these conditions. Research physicians, nutritionists, pharmacists, and biologists can benefit from the detailed information provided at the different levels of targets identified to treat metabolic diseases and conditions.

  • Protein Termini Part A

    • 1st Edition
    • Volume 718
    • English
    Protein termini represent a major route to protein regulation. From the moment the very first amino acid of a polypeptide chain exits the ribosome there is potential for steering from the cellular environment. This volume of Methods in Enzymology Modifications and Targeting of Protein Termini focuses on Protein N-termini and C-termini and their modifications which include acetylation, arginylation, myristoylation and oxidation. Also, the impact of terminal modifications is covered, in particular the impact on protein turnover and the ubiquitin E3 ligases which specifically recognize protein N-termini (N-degrons) and C-termini (C-degrons). In addition to the detailed methods and laboratory protocols, the chapters include informative overviews and reviews of the different subfields.

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