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Elsevier

Books in Life sciences

  • Formulating and Implementing Pharmaceutical Pricing Policies

    Challenges, Case Studies and Lessons Learned from Medicine Price Control
    • 1st Edition
    • Zaheer-Ud-Din Babar
    • English
    Provides readers with a framework to understand and analyze several medicine pricing policies. Through case studies from countries across geographies and income tiers, this book explores the challenges and opportunities related to price control experiences. Studying global policies this book discusses approaches, strategies, and the underlying pharmaceutical pricing practices used to provide advice for formulating highly effective policies. Alongside the cases, this book covers appropriate research methods for pricing analysis, the essential components of pricing policy, data quality, and the generic structure of a pharmaceutical pricing policy.

  • Ticks of the Middle East

    Taxonomy, Biology, Ecology, Medical, and Veterinary Significance
    • 1st Edition
    • Kosta Y. Mumcuoglu + 3 more
    • English
    Ticks of the Middle East: Taxonomy, Biology, Ecology, Medical and Veterinary Significance consolidates the knowledge of ticks and tick-borne diseases in the Middle East region, with particular emphasis on their taxonomy, synonyms, distribution, ecology, and medical and veterinary significance. This book explores the history of tick research and the geoclimatic conditions of Middle Eastern countries. It also provides distribution maps of each tick species within the Middle East region and a list of ticks found in each country. Written by an international team of experts in the field, Ticks of the Middle East: Taxonomy, Biology, Ecology, Medical and Veterinary Significance provides a concise and authoritative resource on tick species in the region.

  • The Neuroscience of Feelings: Brain-Heart Connectivity in Neurodegenerative Diseases

    • 1st Edition
    • Volume 294
    • English
    The Neuroscience of Feelings: Brain-Heart Connectivity in Neurodegenerative Diseases, Volume 294 explores the complex interplay between emotions and brain function+G147, covering topics such as The role of heart-brain connectivity in neurodegeneration: mechanisms and impacts, Cardiovascular influence on cognitive decline: the heart's role in neurodegenerative disorders, Autonomic nervous system dysregulation in neurodegenerative diseases: bridging brain and heart, Heart rate variability as an indicator of brain health in neurodegeneration, and much more.Other sections cover Emotional stress and cardiovascular health: impacts on neurodegenerative disease progression, Exploring heart-brain axis alterations in Parkinson’s disease, Cardiac biomarkers as predictors of cognitive decline in neurodegenerative conditions, Heart-brain synchrony: therapeutic implications for neurodegenerative disease, and Neurocardiology and neurodegenerative diseases: emerging research on emotional regulation and brain-heart connectivity.

  • Immuno-oncology and Immunotherapy Part D

    • 1st Edition
    • Volume 196
    • English
    Immuno-oncology and immunotherapy, Part D, Volume 196 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Investigating the endothelial-immune axis in cancer, Establishing Tyro3, Axl, and Mertk Chinese Hamster Ovary (CHO) Reporter Cell Lines for Cancer Immunology and Therapeutic Applications, Amino acid analog-based labelling of the immunomodulatory cancer secretome, Human and mouse iNKT cell expansion and engineering with viral vectors, Next-generation deconvolution of the tumor microenvironment with omnideconv, and much more.Additional sections cover Comprehensive prediction of tumor neoantigens with NextNEOpi, Ex vivo profiling of organotypic tumor spheroids in 3D microfluidic culture, A flow cytometry-based assay for evaluation of T cell activation and degranulation in coculture systems, An adenosine production assay suitable for 2D and 3D cancer cell culture, Determination of lactate in the tumor interstitial fluid, Combined in vitro differentiation and cell sorting-based isolation of highly pure mouse bone marrow-derived basophils, Organ-on-Chip immunostaining method for three-dimensional identification and study of immune cells responding to drug-treated tumor cells, and much more.

  • New Developments in Redox Biology

    Fundamental Roles in Health and Disease
    • 1st Edition
    • Asim K. Duttaroy + 1 more
    • English
    New Developments in Redox Biology: Fundamental Roles in Health and Disease serves as a vital resource for understanding the profound impact of the redox system on human biology. In the book, readers are introduced to the intricate balance of oxidative stress, the delicate mechanisms of antioxidant defense, and their pivotal roles in cellular function. This book meticulously unpacks the connections between redox biology and the progression of health, aging, and disease, offering researchers and enthusiasts alike a window into these complex physiological processes.Aside from illuminating oxidative dynamics, this book delves into emerging trends, therapeutic potential, and the integration of redox principles in developing medical interventions, highlighting its relevance in advancing human health.

  • Primary Brain Tumors in Adults: Advances in Mechanistic Understanding, Evaluation, and Management

    • 1st Edition
    • Volume 166
    • English
    Primary Brain Tumors in Adults: Advances in Mechanistic Understanding, Evaluation, and Management, Volume 166 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Molecular drivers in primary brain tumor formation, Novel CSF pathways in the glioma (DIPG), Volumetric analysis in low grade gliomas and other advanced MR imaging techniques, Liquid biopsy in the diagnosis of primary brain tumors, Intraoperative imaging techniques to improve tumor detection, and much more.Additional chapters focus on Supramaximal resection in primary brain tumors, Radiotherapeutic approaches: IMRT, re-irradiation, Molecularly driven therapies in the treatment of primary brain tumors, and Changes in the immune microenvironment and immunotherapeutic strategies in the treatment of gliomas.

  • Myasthenia Gravis, Part A

    • 1st Edition
    • Volume 182
    • English
    Myasthenia Gravis, Part A, Volume 182 in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as the Structure of the NMJ and Neuromuscular Transmission, Neuromuscular Junction and the Complement System, Regulation of the Autoimmune Response, The Thymus, Antibodies/Subclasse... (IgG) and Antigens, Cell Models of MG, Mouse Models of EAMG and Passive Immunization, Epidemiology of Myasthenia Gravis, Special Populations: Juvenile, Early, Late, and Very Late-Onset, Blood and Digital Biomarkers in MG, Lambert-Eaton Myasthenic Syndrome, and Congenital Myasthenic Syndromes.

  • Sustainability in the Manufacturing of Pharmaceuticals

    • 1st Edition
    • Dimitrios A. Lamprou
    • English
    Sustainability in Pharmaceutical Manufacturing is a groundbreaking reference for the pharmaceutical industry. Currently lagging behind other manufacturing sectors, pharmaceutical production requires significant changes in areas such as manufacturing methods, waste management, packaging, and supply chain. This book compiles cutting-edge research from leading global experts, offering scientific insights and innovative strategies to revolutionize sustainability in pharmaceuticals. It explores the transformative potential of the circular economy, lifecycle management, and resource optimization for maximum efficiency and minimal environmental impact.The book delves into green chemistry, highlighting alternative solvents and methods for drug production. It emphasizes novel microfluidic and additive manufacturing techniques, utilizing bio-based sustainable polymers and materials. Chapters on greener drug discovery, development, and scaling processes provide the most current research at each production stage. This invaluable resource enables researchers in academia and industry to make informed choices, enhancing their manufacturing practices and shaping the future of sustainability in the pharmaceutical sector.

  • Enfermedad vascular cerebral en jóvenes

    • 1st Edition
    • Fernando Barinagarrementeria Aldatz + 1 more
    • Spanish
    Enfermedad vascular cerebral en jóvenes constituye una contribución inédita en lengua española sobre un tema tan específico como trascendente: la enfermedad vascular cerebral (EVC) en la población joven, escrita por autores internacionales líderes en los diferentes aspectos de este complejo tema. En las últimas décadas, la EVC en jóvenes ha dejado de ser una rareza clínica para convertirse en un problema creciente, con implicaciones significativas por lo que hace a su diagnóstico y manejo. El adecuado abordaje clínico y tecnológico es indispensable para la solución de esta compleja patología, y este título ofrece las herramientas necesarias para su estudio. La presente obra proporciona una revisión exhaustiva de los diferentes aspectos de la enfermedad, abordando su incidencia y factores de riesgo, tanto clásicos como nuevos. También se revisan las diferentes etiologías, y se proporciona un marco para la toma de decisiones clínicas y el manejo de los trastornos cerebrovasculares tanto frecuentes como infrecuentes en esta población.

  • Neurotoxicity of Solvents

    • 1st Edition
    • Volume 14
    • English
    Neurotoxicity of Solvents, Volume Fourteen highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including the Effect of toluene on memory: A focus on humans, experimental models and treatment approaches, Neurotoxicological Mechanisms of Ethanol, Neurobehavioral Aspects and Methodology of Solvents, Organic solvents and neurodegenerative diseases: exploring a possible link, Neurotoxicity of propylene ethers, An ecotoxicological view on solvents neurotoxicity, and The olfactory system as a target of solvent toxicity.

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