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Elsevier

Books in Life sciences

  • The Cardiovascular System

    From Bench to Bedside
    • 1st Edition
    • Hussein Hassan Sabit
    • English
    The series "Stem Cell Innovation in Health & Disease" is a timely and fascinating collection of information and new discoveries and provides a contemporary snapshot album from the fast-moving field of regenerative medicine and stem cell therapeutics. The Cardiovascular System, Volume 6 addresses the recent data accumulated on the potential applications of stem cells to treat diseases and disorders of the cardiovascular system. This volume will highlight the recent developments of cutting-edge in vitro and in vivo research tools and approaches, including the human and murine organoid cultures, genetic editing in vitro and in vivo, human iPSC models of diseases, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to treat cardiovascular system disorders and diseases. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine, and organ transplantation; and is contributed by world-renowned authors in the field.

  • Targeted Protein Degradation Technologies

    • 1st Edition
    • Jiangjiang Qin + 2 more
    • English
    Targeted Protein Degradation Technologies offers a comprehensive exploration of the field of targeted protein degradation, from its latest scientific advancements to its potential therapeutic applications. This book begins with a foundational introduction to the mechanisms of protein degradation, followed by an in-depth look at both protease-mediated and lysosome-mediated degradation pathways. The text delves into a range of cutting-edge technologies, including PROTAC, AbTAC, molecular glues, hydrophobic tagging, LYTAC, GlueTAC, and AUTAC. It then explores the development of degraders for specific proteins, such as signal transduction receptors, membrane proteins, and transcription factors. This book concludes with a focused discussion on the clinical applications of targeted protein degradation and provides an insight into the future directions for this field.This book serves as an invaluable resource for researchers and professionals in molecular biology, cell biology, and related disciplines, particularly those involved in protein degradation and the development of novel therapeutic strategies.

  • Reproductive Immunogenetics: A Molecular and Clinical Overview, Vol. 3

    Immunogenetic Factors and Signaling Pathways in Recurrent Pregnancy Loss
    • 1st Edition
    • Shafat Ali + 2 more
    • English
    Immunogenetics: A Molecular and Clinical Overview, Vol. 3, Immune Cells and Immunotherapeutics in Recurrent Miscarriage provides an overview of the scientific knowledge, achievements, and findings in the field of immunogenetics of recurrent pregnancy loss. With a strong focus on the role immune cells can play in recurrent pregnancy loss, the book also examines immune therapeutic aspects. In fifteen chapters, the book describes the roles of both helper cells, nature killer cells, lymphoid cells, regulatory cells and macrophages in recurrent pregnancy loss. In addition, it describes clinical outcomes of several therapies and gives insight into new treatments. This new release is a valuable resource for health professionals, scientists and researchers, and all those who wish to broaden their knowledge in the allied field.

  • Reproductive Immunogenetics: A Molecular and Clinical Overview

    Immune Cells and Immunotherapeutics in Recurrent Pregnancy Loss
    • 1st Edition
    • Shafat Ali + 2 more
    • English
    Immunogenetics: A Molecular and Clinical Overview: Immunogenetic Factors and Signaling Pathways in Recurrent Miscarriage, Volume Four provides an overview of the scientific knowledge, achievements, and findings in the field of immunogenetics of recurrent pregnancy loss. With a strong focus on the role immune cells can play in recurrent pregnancy loss, the book also examines immune therapeutic aspects. In seventeen chapters, the book describes the roles of several different signaling pathways and the role of JLA and microRNAs in recurrent pregnancy loss. Several chapters are dedicated to the role autoimmune antibodies play in recurrent pregnancy loss. This book is a valuable resource for health professionals, scientists, researchers, and all those who wish to broaden their knowledge in the allied field.

  • Cell Migration in Development

    • 1st Edition
    • Volume 164
    • English
    Cell Migration in Development, Volume 163 highlights new advances in the field, with chapters written by an international board of authors who update on high-profile topics such as. Single-cell migration in development - lessons from germ-cells, Lipid/membrane regulation during cell migration and invasion, Remodeling of the extracellular matrix and cell-matrix adhesion during collective cell migration, From cessation of neural crest migration to onset of gangliogenesis, Collective migration in confined spaces: the case of trunk neural crest, From single to collective: the mechanisms underlying cell migration in early development, Direct and indirect roles of Nodal signaling in developmental cell migration.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 130
    • English
    Advances in Applied Microbiology, Volume 130 continues the comprehensive reach of this widely read and authoritative review source in microbiology where users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

  • Non-coding RNA

    • 1st Edition
    • Volume 214
    • English
    Non-coding RNA, Volume 214 in the Progress in Molecular Biology and Translational Science series, highlights advances in the field, with this new volume presenting interesting chapters on topics such as An introduction to non-coding RNAs, Non-coding RNAs in Eutherians and Livestocks, Artificial intelligence and machine learning heuristics for discovery of ncRNAs in humans, Non-coding RNAs in Plants, Epigenetic and experimental approaches influencing ncRNAs, Noncoding RNAs in bacteria, Dissecting ncRNA pathways and omics integration, Structural prediction of potent ncRNAs, Artificial intelligence and machine learning heuristics for discovery of ncRNAs in humans, Tools and Databases for non-coding RNAs, and Physiogenomics and genetic landscape of ncRNAs.

  • The Mastery of Bile Duct Injury

    • 1st Edition
    • Qalandar H. A. Kasnazani
    • English
    The Mastery of Bile Duct Injury is a comprehensive medical reference that explores the various aspects of biliary injuries, encompassing anatomy, causes, classifications, clinical management, and surgical procedures, with a particular focus on complications arising from laparoscopic cholecystectomy. It not only provides a meticulous dissection of biliary injuries but also navigates through the labyrinth of diagnostic modalities and therapeutic approaches, illuminating the path toward enhanced patient care, surgical precision, and the future of research in this area.Through its detailed examination, this authoritative reference serves as an invaluable resource for the complexities of biliary pathology empowering readers to navigate the challenges inherent in hepatobiliary surgery. Beginning with the historical evolution of cholelithiasis and extending to the impact of laparoscopic cholecystectomy, this book provides detailed insights into the intrahepatic and extrahepatic biliary systems, offering a foundation for understanding the complexities of biliary injuries encountered during surgical procedures.By addressing classification, management, and prevention strategies, this book serves as an invaluable resource for optimizing patient outcomes and minimizing complications in hepatobiliary surgeries. In a field where staying current with best practices is essential, The Mastery of Bile Duct Injury emerges as a vital reference, catering to the needs of surgeons, clinicians, and researchers alike. Its interdisciplinary approach and thorough examination of topics make it an indispensable resource for anyone involved in hepatobiliary surgery or seeking a deeper understanding of biliary injuries.

  • Cerebral Metastases: Translational Advances, Evaluation and Management

    • 1st Edition
    • Volume 165
    • English
    Cerebral Metastases: Translational Advances, Evaluation and Management, Volume 165 in this ongoing series, highlights new advances in the field, with this new volume covering many interesting topics, including Molecular Drivers in CNS metastasis, Role of the tumor microenvironment in CNS metastatic disease, Advanced Imaging to improve early diagnosis and evaluate treatment response, Liquid biopsy in early detection of CNS metastasis, Precision medicine approaches to CNS metastatic disease, IMRT/conventional RT, Single and hypofractionated SRS, Brachytherapy for recurrent metastases, LITT for treatment of active brain metastasis and radiation necrosis, and much more.Other topics covered include Minimally-invasive surgical approaches in the management of brain metastases.

  • Mitochondria and Neurotoxicity

    • 1st Edition
    • Volume 13
    • English
    Mitochondria and Neurotoxicity, Volume Thirteen in the Advances in Neurotoxicology series, presents interesting chapters written by an international board of authors. Chapters in this new release include Introduction to mitochondrial toxicity: form, function, and signaling, Respirometry parameters as indicators of neurotoxicity, Pesticide exposure and hippocampal neurogenesis: Role of ER stress and mitochondria, Gene Therapy Approaches to Abrogate Pathogenic Mechanisms in Parkinson’s disease, Mitochondrial dysfunction induced by trichloroethylene in Parkinson’s disease, and Gut-brain axis inflammation induced by mitochondrial toxicants.

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