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Elsevier

Books in Life sciences

  • Neuroscience Research in Short-Duration Human Spaceflight

    • 1st Edition
    • Bader Shirah
    • English
    Neuroscience Research in Short-duration Human Spaceflight encapsulates a groundbreaking neuroscience portfolio conducted during the Axiom Mission 2 in May 2023, offering an examination of the effects of short-duration orbital spaceflight on aspects of the human brain. Addressing limitations in existing literature, the research includes astronauts of diverse ages, genders, and ethnic backgrounds, broadening the understanding of the impact of spaceflight on human physiology. A significant aspect of the suite of studies is the validation of two novel devices providing unprecedented information about the pupillary light reflex and neuroimaging in microgravity: automated pupillometry and functional near-infrared spectroscopy. The portfolio extends to explore spaceflight-associat... neuro-ocular syndrome, offering valuable contributions to the evolving field of space medicine. Furthermore, the research delves into the utilization of electroencephalograp... to monitor brain activity, acknowledging its potential in assessing cognitive health, stress levels, and mental workload in real time. Despite promising prospects, challenges in electroencephalograp... system adaptability within the International Space Station environment are highlighted, emphasizing the need for specialized design considerations. In addition, analysis is extended into the molecular biomarkers through minimally invasive blood monitoring. This book represents a pivotal advancement in space neuroscience, laying the foundation for safer space travel and fostering the development of monitoring tools crucial to observing adverse changes and potentially developing countermeasures that can aid in the establishment of a permanent human presence beyond Earth.

  • Medical Image and Signal Analysis in Brain Research

    • 1st Edition
    • Volume 290
    • English
    Progress in Brain Research, Volume 290 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this release include Image Analysis for Spinocerebellar Ataxia Type 3, Brain structural network modular and connectivity alterations in subtype of patients with migraine, Brain Functional Networks and Structures that Categorize Type 2 Bipolar Disorder and Major Depression, Reinforcement Learning Classification in fNIRS Signal of Olfactory Stimulated, The method of brain-computer interface using the forehead instead of the visual area to receive SSVEP signals and signal processing, and more.Additional chapters cover The relationship between flash-induced SSVEP in DELTA frequency band and sleep, Enhancing Facial Feature De-Identification in Multi-Frame Brain Images: A Generative Adversarial Network Approach, Comparative Analysis of MRI Markers in Heat and Mechanical Pain Sensitivity, and Analysis of the Difference Between Alzheimer’s Disease, Mild Cognitive Impairment and Normal People by Using Fractal Dimensions and Small-World Network.

  • The Physics of Protein Structure and Dynamics

    When and Why Proteins Fold or Don’t Fold
    • 1st Edition
    • Reinhard Schweitzer-Stenner
    • English
    The Physics of Protein Structure and Dynamics looks at various aspects of protein structure and dynamics from a physico-chemical point of view. It goes into some depth regarding the description of non-covalent forces that determine the relative stability of folded and unfolded proteins. Anharmonic protein dynamics involving motions between different minima of a rugged Gibbs energy landscape is described in great detail. The book combines various aspects of the protein folding/unfolding processes with an overview of intrinsically disordered proteins, which have attracted considerable interest of the protein community over the last 25 years but are thus far underrepresented in classroom-oriented textbooks. The book looks at protein folding and intrinsically disordered proteins as heavily interrelated topics that need to be viewed together. Furthermore, it presents some basic physico-chemical aspects of protein/peptide self-assembly into nanoscale fibrils. Intrinsically disordered peptides and proteins play a major role particularly in aggregation and self-assembly processes that lead to various diseases (Alzheimer, Parkinson, Huntington, Mad-Cow). Therefore, the relevance of protein disorder for protein self-assembly deserves a closer look. Protein self-assembly cannot be separated from protein folding since it is frequently the product of misfolding. With regard to modern theories, the folding processes are linked to insights on protein dynamics and the discovered relationship between proteins and spin glasses.

  • Inherited White Matter Disorders and Their Mimics

    • 1st Edition
    • Volume 204
    • English
    Inherited White Matter Disorders and Their Mimics, Volume 204 discusses where imaging abnormalities and pathology lie predominantly in the CNS white matter. Many acquired causes, such as multiple sclerosis, are readily diagnosed and familiar to the majority of neurologists. However, less common acquired causes and genetic disorders (the leukodystrophies and genetic leukoencephalopathie... often present a diagnostic challenge. The evaluation of patients with White matter disorders (WMDs) has evolved enormously in recent decades, due to advances in genetics, radiology, and the development of treatments for specific disorders. This book brings together WMD research, spanning basic science, molecular genetics, and clinical and radiological phenotyping.This volume presents both common WMDs and rare disorders according to their presentations or pathophysiology. Chapters lay out the clinical and radiological presentation of the disorder, followed by genetics and diagnostics, and finally discussion of pathophysiology and treatment. Chapter contain imaging, clinical pearls to diagnosis, and reference tables for genotype-phenotype correlation. For diagnostic work-up, easy to read algorithms are presented as well as clear guidance on indications for treatment, where applicable.

  • Autism Autonomy

    In Search of Our Human Dignity
    • 1st Edition
    • Elizabeth B. Torres
    • English
    Autism Autonomy: In Search of Our Human Dignity provides a new and unifying methodological framework and discusses machine learning and biometrics techniques to diagnose, characterize, and treat patterns of sensory motor control underlying autism symptoms. With the hope of improving basic research in these areas, this volume will allow readers to design better interventions and provide awareness of a number of new technologies used in the autism field. Wearable bio-sensing technologies, machine learning, and AI methods are all discussed regarding their applications to provide better self-awareness, interaction, diagnosis, and prognosis.This volume is useful for researchers and clinicians interested in learning about these new technologies and how to enhance machine learning use in ASD for the betterment of patients.

  • Advances in Marine Biology

    • 1st Edition
    • Volume 97
    • English
    Advances in Marine Biology, Volume 97, the latest release in this serial that highlights new advances in the field, including comprehensive chapters written by an international board of authors.

  • Effective Approaches to Global Health Issues

    • 1st Edition
    • Manoj Sharma + 1 more
    • English
    Effective Approaches to Global Health Issues is a comprehensive, interdisciplinary book that explores diverse topics in global health. It serves as a valuable resource for understanding the complexities and challenges associated with global health from various perspectives. The book delves into historical contexts, health indicators, cultural influences, behavioral factors, communicable and non-communicable diseases, malnutrition, nutritional deficiencies, obesity, environmental health, population issues, women's and children's health, mental well-being, global health systems, and emerging issues in the field. It goes beyond a mere recitation of topics and provides an engaging narrative that examines the interconnectedness of global health issues.This is an essential reference for students, researchers, and professionals involved in public health, international development, and related disciplines. By providing a comprehensive understanding of global health issues and potential solutions, this book equips readers with the knowledge and tools to address the complex challenges of global health in their respective fields.

  • Planning, Writing and Reviewing Medical Device Clinical and Performance Evaluation Reports (CERs/PERs)

    A Practical Guide for the European Union and Other Countries
    • 1st Edition
    • Joy Frestedt
    • English
    A Practical Guide to Planning, Writing, and Reviewing Medical Device Clinical Evaluation Reports guides readers through clinical data evaluation of medical devices that is in compliance with the EU MDR requirements and other similar regulatory requirements throughout the world. This book brings together knowledge learned as the author constructed hundreds of CERs and taught thousands of learners on how to conduct clinical data evaluations. This book will support training for clinical engineers, clinical evaluation scientists, and experts reviewing medical device CERs, and will help individual writers, teams and companies to develop stronger, more robust CERs.

  • Agroecology of Edible Weeds and Non-Crop Plants

    Ecology and Socioeconomic Potential of the Associated Plant Biodiversity
    • 1st Edition
    • Roland Ebel + 1 more
    • English
    Agroecology of Edible Weeds and Non-Crops: Ecology and Socio-Economic Potential of Plant Biodiversity is the first book to move beyond the ethnobotanical aspect of under-utilized non crops to explore how to optimize their potential. With case studies of edible weeds and non-crop plants from around the world, including Europe and North America, in urban as well as rural settings, the book highlights the global opportunities provided by these plants. The book includes much needed information for identifying, maintaining, and benefitting from these plant species. It is ideal for agricultural professionals, educators, researchers, and students.Those interested in increasing the diversity of the farming landscape and food systems by means of edible non-crop plants have access to a plethora of information on the ethnobotany of these species. Yet little to no information exists on the agroecological requirements and potential benefits of underutilized edible non-crop plants in the context of sustainable farming systems. This book fills that knowledge gap from identifying edible weeds and non-crop plants, to exploring the ways these plants can be used to economically improve nutrition.

  • Integrative Omics in Parkinson's Disease

    • 1st Edition
    • Joanne Trinh
    • English
    Integrative Omics in Parkinson’s Disease provides a comprehensive understanding of the current literature on high-throughput technologies relating to discoveries for Parkinson's disease etiology. This emerging field uses large omics datasets to investigate the etiology of Parkinson’s disease and other forms of parkinsonism. The book traces the evolution of omics technologies from the discovery of monogenic Parkinson's disease forms. Chapters delve into genomics, transcriptomics, epigenomics, artificial intelligence, and gene-environment interactions. Furthermore, it examines the potential therapeutic applications of these advancements and provides insights into the future of omics research in Parkinson's disease.

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