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Elsevier

Books in Life sciences

  • Genetics and Epigenetics of Genitourinary Diseases

    • 1st Edition
    • Seyed Mohammad Kazem Aghamir
    • English
    Genetics and Epigenetics of Genitourinary Diseases aims to provide a comprehensive collection of data on genetics and epigenetics in almost all genitourinary diseases for researchers, clinicians, and graduate students.This book discusses several genetic and epigenetic changes like DNA methylation, mutations, single nucleotide polymorphisms, DNA rearrangements, chromosomal remodeling, microsatellite instability, and chromosomal instability (CIN) in genitourinary cancers.This book is split into 18 chapters, beginning with the importance of genetics and epigenetics in genitourinary diseases. It then goes on to cover the genetics and epigenetics of various diseases and tumors. Certain chapters present novel techniques of next-generation sequencing (NGS). Furthermore, RNA-Seq is discussed as a sequencing technique that uses NGS to reveal the presence and quantity of RNA in a biological sample.This book is a valuable resource for researchers, practitioners, and students in genetics and epigenetics who want to broaden their understanding of the field.

  • The Evolution of Immunotherapy Against Tumors

    An Historical Approach
    • 1st Edition
    • Domenico Ribatti
    • English
    The Evolution of Immunotherapy Against Tumors: An Historical Approach summarizes the literature concerning the development of the theory of immune surveillance against tumors. It discusses the evidence for and against this theory, along with the concept of immunoediting. Finally, current approaches in anti-tumor immunotherapy will be analyzed.The immune system plays a major role in the surveillance against tumors. To avoid attack from the immune system, tumor cells develop different strategies to escape immune surveillance. Evidence of immune surveillance comes from both animal models and clinical observations. Mice with a wide variety of immunodeficiencies have a high rate of tumor incidence and are more susceptible to transplanted or chemical carcinogen-induced tumors. Immunosuppressed patients have a high incidence of tumors. However, many patients develop cancer even in the presence of an apparently normal immune system. This indicates that tumor cells can escape immune surveillance.

  • Rowan's Primer of EEG

    • 3rd Edition
    • Lara V. Marcuse + 2 more
    • English
    **Selected for 2025 Doody’s Core Titles® in Neurology**Practical... brief, and easy to understand, Rowan's Primer of EEG, 3rd Edition, teaches the difficult technical aspects of how to perform and interpret EEGs. Direct, concise text, numerous illustrations and teaching points, and an extensive video library make this up-to-date reference a valuable resource for students, residents, neurologists, and epileptologists alike.

  • Vaccines in Aquaculture

    Development, Production, and Applications
    • 1st Edition
    • Baskaralingam Vaseeharan + 1 more
    • English
    Vaccines in Aquaculture: Development, Production, and Applications acknowledges the crucial part that aquatic vaccines play in disease control for the sustainable future of aquaculture. Vaccination progression has become the most important method for disease prevention and effective prophylaxis based on stimulation of the immune systems of key aquaculture species. This book provides detailed information about the evaluation, mass production, and commercialization of aquatic animal vaccines, as well as specific descriptions of the correct use of vaccines against the most important microbial diseases of aquatic animals.Written by a leading expert in aquatic animal health biotechnology, this book is systematically organized for effective delivery of its major themes. The book starts by providing an overview on aquaculture vaccine history, evolution, and characteristic features before describing the various types of vaccines and vaccination methods in the industry. Latter sections discuss aquatic vaccine development, recent developments and challenges, mass production, and commercialization. The book concludes with an examination of the challenges associated with large-scale production, commercialization, and ethical and legal considerations.

  • From Anatomy to Function of the Central Nervous System

    Clinical and Neurosurgical Applications
    • 1st Edition
    • Brandon Matteo Ascenzi
    • English
    From Anatomy to Function of the Central Nervous System: Clinical and Neurosurgical Applications features neuroradiologic images that represent today, one of the most effective resources able to detect the anatomy of the nerve structures. Simultaneously featuring neuroimages, readers can study the functional aspects of the entire central nervous system with detailed captions that describe in detail how to use and interpret them. This book includes images of the brain dissected with the Klingler’s method and white matter fiber dissection. By integrating the anatomo-functional description with the synaptic organization of the CNS, this reference is useful for anyone who wants to understand how the activity of a nerve structure arises, describing its microstructure, neurotransmitter phenotype, and neural activity. It also features descriptions of pathologic conditions which result from neuroanatomical and/or neurofunctional alterations and includes neurosurgical aspects.

  • Epigenetic Regulation of Cancer-Part C

    • 1st Edition
    • Volume 387
    • English
    Epigenetic Regulation of Cancer, Part C, Volume 389 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of hot topics, including Epigenetic biomarkers in breast cancer, Contribution of epigenetics to virus-driven cancer, Cancer metabolism and epigenetics, Technologies for epigenome editing, Epigenetics and cancer stemness, Epigenetic modifications in obesity-associated cancers, Epigenetics in cf microRNA in blood of solid tumors, Integrative analysis of transcriptome, chromatin accessibility, cell surface antigen in single cell level for AML, and more.Additional chapters cover Epigenetics in lung cancer, Gene Regulatory Mechanisms underlying therapy resistance in Cancer, Role of miRNAs as epigenetic regulators of immune checkpoints in cancer immunity, Epigenetic contributions to Acute myeloid leukemia (AML), Contribution of epigenetics to chemoresistance, Epigenetic contribution to the relationship between obesity and cancer, and Epigenetic regulation in ovarian cancer.

  • Intelligent Computing Techniques in Biomedical Imaging

    Methods, Case Studies, and Applications
    • 1st Edition
    • Bikesh Kumar Singh + 1 more
    • English
    Intelligent Computing Techniques in Biomedical Imaging: Methods, Case Studies, and Applications provides comprehensive and state-of-the-art applications of Computational Intelligence techniques used in biomedical image analysis for disease detection and diagnosis. The book offers readers a stepwise approach from fundamental to advanced techniques using real-life medical examples and tutorials. The editors have divided the book into five sections, from prerequisites to case studies. Section I presents the prerequisites, where the reader will find fundamental concepts needed for advanced topics covered later in this book. This primarily includes a thorough introduction to Artificial Intelligence, probability theory and statistical learning. The second section covers Computational Intelligence methods for medical image acquisition and pre-processing for biomedical images. In this section, readers will find AI applied to conventional and advanced biomedical imaging modalities such as X-rays, CT scan, MRI, Mammography, Ultrasound, MR Spectroscopy, Positron Emission Tomography (PET), Ultrasound Elastography, Optical Coherence Tomography (OCT), Functional MRI, Hybrid Modalities, as well as pre-processing topics such as medical image enhancement, segmentation, and compression. Section III covers description and representation of medical images. Here the reader will find various categories of features and their relevance in different medical imaging tasks. This section also discusses feature selection techniques based on filter method, wrapper method, embedded method, and more. The fourth section covers Computational Intelligence techniques used for medical image classification, including Artificial Neural Networks, Support Vector Machines, Decision Trees, Nearest Neighbor Classifiers, Random Forest, clustering, extreme learning, Convolution Neural Networks (CNN), and Recurrent Neural Networks. This section also includes a discussion of computer aided diagnosis and performance evaluation in radiology. The final section of Intelligent Computing Techniques in Biomedical Imaging provides readers with a wealth of real-world Case Studies for Computational Intelligence techniques in applications such as neuro-developmental disorders, brain tumor detection, breast cancer detection, bone fracture detection, pulmonary imaging, thyroid disorders, imaging technologies in dentistry, diagnosis of ocular diseases, cardiovascular imaging, and multimodal imaging.

  • Nanophototherapy

    Preparations and Applications
    • 1st Edition
    • Panchanathan Manivasagan + 2 more
    • English
    Nanophototherapy: Preparations and Applications provides a comprehensive overview of the various multifunctional nanoparticles used for phototherapy, with an emphasis on fundamental nanotechnology and the latest research of photothermal therapy (PTT) and photodynamic therapy (PDT). The different types of phototherapeutic nanomaterials are thoroughly described, along with their structural features and synthesis. This is the first book to cover nanomaterial-based phototherapy for both cancer and bacterial infections. It is an essential resource for researchers, academics, and professionals interested in the potential of multifunctional nanomaterials for therapeutic applications.

  • Linseed

    A Multipurpose-Multisector Crop of Industrial Significance
    • 1st Edition
    • Sapna Langyan + 1 more
    • English
    Linseed: A Multipurpose-Multise... Crop of Industrial Significance provides a general overview of linseed as a multipurpose-multise... crop for obtaining a number of valuable products. The book's sections present the use of linseed as food products and discuss a number of important topics, including genetic engineering and breeding advances, pre-harvest processing methods, advanced extraction and quality assessment, metabolic engineering, bioactivity, new food product development, chemistry, and functionality. The book also covers the use of linseed in the textile sector and modified linseed oil products, animal feed products, cosmetics, and personal use products, along with their industrial significance.Food waste and the challenges of linseed crop production and processing into a number of industrial products are also discussed. This book acts as a comprehensive resource for food scientists, researchers, scholars, and industrial people related to food, nutraceutical, cosmetics, pharmaceuticals, textiles, and health practitioners, especially dieticians and nutritionists.

  • Vesicle Trafficking in Eukaryotes

    • 1st Edition
    • Volume 93
    • English
    Current Topics in Membranes, Volume 93 highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Receptor-mediated endocytosis in kidney cells during physiological and pathological conditions, Membrane transport and endocytosis in malaria parasites, Impact of Coat Protein on Evolution of Ilarviruses, and Membrane Contact Sites.

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