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Elsevier

Books in Life sciences

  • An Integrated Guide to Human Drug Metabolism

    From Basic Chemical Transformations to Drug-Drug Interactions
    • 1st Edition
    • Mark Ashton + 3 more
    • English
    An Integrated Guide to Human Drug Metabolism: From Basic Chemical Transformations to Drug-Drug Interactions uses the chemistry of each of the metabolic transformations to underpin the discussion of drug interactions with foods, herbal medicines, and other drugs. Each of the human metabolic processes are covered, employing examples drawn from known metabolic transformations of drugs used clinically. The clinical relevance of metabolism is discussed, focusing on appropriate prescribing (age-related dosage adjustments, routes of administration, and personalized medicines). Appropriate for use in the classroom or for self-study, this book is for students and researchers needing a reference for interdisciplinary research in drug interactions.Metabol... is at the center of personalized medicine, as it is a governing factor in the response of the patient to a drug. For example, does the patient express the genes, and so enzymes, which are responsible for the metabolism of a drug? Do they express the genes responsible for the bioactivation of a prodrug into its active form? Examples of clinically used agents for which metabolic phenotyping is essential will be used to highlight the increasing necessity for understanding the genetic profile of individual patients. This book includes questions and answers to gauge learning of each chapter, real-life case studies, and the basic science as a basis for the discussion of clinical aspects.

  • Bioreactor Design Concepts for Viral Vaccine Production

    • 1st Edition
    • Surajbhan Sevda + 1 more
    • English
    Bioreactor Design Concepts for Viral Vaccine Production covers a range of interdisciplinary chapters from the engineering perspective of bioreactor design to the biotechnological perspectives of vector design for vaccine development. The book covers bioreactor concepts such as static systems, single-use systems, stirred tanks, perfusion, wave and packed-beds. It reviews options for efficient and economical production of human vaccines and discusses basic factors relevant for viral antigen production in mammalian cells, avian cells, and insect cells. This book will be a great resource for those interested in implemented novel bioreactor design or experimental schemes towards intensified or/and enhanced vaccine production.

  • Advanced Biologic Drugs and Manufacturing Process

    • 1st Edition
    • Basanta Kumara Behera
    • English
    Advanced Biologic Drugs and Manufacturing Process explains biologic drugs, their pharmaceutical charters, and their significance in curing life-threatening chronic diseases. It also provides the latest information on the use of biological drugs for the treatment of numerous diseases and conditions and their most advanced therapies available, including how biologics have impacted cancer therapy, delayed or reversed the course of immune-related conditions, and changed the lives of those with rare chronic diseases. In addition, the book explains how immunotherapy is used for the treatment of diseases by activating or suppressing the immune system.Scientists working on the front lines in the biotechnology industry are provided with an overview on stable production processes and how to monitor the value chain transfer process of biologic drug for better return, in terms of profit. The book also helps researchers and academics on how to develop and update protocols related to testing, quality control, and quality assurance to obtain highly purified biopharmaceuticals or vaccines.

  • Environmental Pollution and Type 2 Diabetes Mellitus

    • 1st Edition
    • Sultan Ayoub Meo
    • English
    Environmental Pollution and Type 2 Diabetes Mellitus elucidates on the global impact of environmental pollution and how it increases diabetes mellitus. Swift urbanization and the industrial revolution have increased environmental pollution to a hazardous level. Environmental pollution is a leading risk factor for several well-known diseases. This book opens venues for students, physicians, researchers, the science community, and policymakers to enhance their knowledge about environmental pollution, weather conditions, climate change, and their impact on insulin resistance and mechanisms allied to Type 2 diabetes mellitus (T2DM).Moreover, this book will provide knowledge about the green space environment and its impact on T2DM.

  • Vertebrate Pattern Formation

    • 1st Edition
    • Volume 159
    • English
    Vertebrate Pattern Formation, Volume 159 in the Current Topics in Developmental Biology series, highlights advances in the field, with this volume presenting interesting chapters on timely topics, including Hox genes patterning the vertebrate body, Endodermal patterning, The use of organoids/gastruloid... to understand development, Cell shape and movements controlling development, Neural crest and placodes in vertebrate development, Patterning of the neural tube, Non-canonical Wnt signaling in axial extension, The control of transitions along the main body axis, Emergence of a left-right symmetric body plan in vertebrate embryos, Formation of the vascular system, Generation of patterns in the paraxial mesoderm, and more.

  • Bioremediation of Emerging Contaminants from Soils

    Soil Health Conservation for Improved Ecology and Food Security
    • 1st Edition
    • Prasann Kumar + 4 more
    • English
    Bioremediation of Emerging Contaminants from Soils: Soil Health Conservation for Improved Ecology and Food Security deals with current challenges of sustainable soil health using eco-friendly approaches. This book provides ways of reducing the chemical burden on the soil by maintaining balance in terms of society, environment, and economy, which are considered basic pillars of sustainability.Desig... to highlight soil health best practices for both environmental and agricultural sustainability, these approaches are also considered important for improving global food security by ensuring safe growing conditions for crops for food and feed. Presented in two parts, this book first highlights emerging contaminants and their sources. The second part explores a variety of steps and tools for addressing contaminated soils, including bio- and phytoremediation options. Case studies in each part provide real-world insights for practical application.

  • Nanobiotechnology for Food Processing and Packaging

    • 1st Edition
    • Jay Singh + 4 more
    • English
    Nanobiotechnology for Food Processing and Packaging covers nanomaterials' application as an eco-friendly, greener, cost-effective and easy handling and management approach that can help prevent various high-level physical, biological and chemical contamination in foodstuff. Written by experts from a multidisciplinary perspective, each chapter addresses nanomaterials' application as a sustainable tool for the management of uncountable food processing and packaging challenges. Sections focus on nanobiotechnology in processing and packaging, considering food quality, safety and management aspects. The book also highlights various preparative methods and antimicrobial/antifu... activities, including the mechanism of the antimicrobial action of various bionanocomposites and food toxin detection nanobiosensor nano additives.Other sections cover possible food toxin detection, food packaging, and materials such as nanomaterials, nanocomposites, carbon-based nanomaterials, polymer-based nanocomposites and various binary and tertiary nanocomposites and their mechanistic approach.

  • Current Omics Advancement in Plant Abiotic Stress Biology

    • 1st Edition
    • Deepesh Bhatt + 3 more
    • English
    Current Omics Advancement in Plant Abiotic Stress Biology investigates the causal molecular factors underlying the respective mechanisms orchestrated by plants to help alleviate abiotic stress. Despite available knowledge of abiotic stresses in crop plants and high throughput tools and biotechnologies, in this book, a systematic effort has been made for integrating omics interventions across major sorts of abiotic stresses with special emphasis to major food crops infused with detailed mechanistic understanding, which would furthermore help contribute in dissecting the interdisciplinary areas of omics-driven plant abiotic stress biology in a much better manner.It focuses on the integration of multi-OMICS biotechnologies in deciphering molecular intricacies of plant abiotic stress, namely drought, salt, cold, heat, and heavy metals in major C3 and C4 food crops. Together with this, the book provides updated knowledge of a common and unique set of molecular intricacies playing a vital role in coping up severe abiotic stresses in plants deploying multi-OMICS approaches.

  • Progress and Prospect of Nanocarriers

    Design, Concept, and Recent Advances
    • 1st Edition
    • Sushil K. Kashaw + 2 more
    • English
    Progress and Prospect of Nanocarriers: Design, Concept, and Recent Advances examines the different nanocarriers that are currently being developed for specific applications in biomedical drug delivery, disease management, diagnosis and therapy. Nanosized drug delivery systems have gained tremendous amounts of clinical interest due to their effective bio-distribution and enhanced pharmacokinetic and selective targeting capability which results in high therapeutic potential, low side effects, and the generation of cost-effective drug delivery systems. Numerous effective nanocarriers have been evolving, including polymeric nanoparticles, liposomes, microspheres, dendrimers, and carbon nanotubes.This book is a helpful reference for scientists and students in the fields of drug delivery, biomaterials and nanomedicine, as well as scientists and engineers in industrial disciplines of drug delivery and drug formulation.

  • Neurovision chez l'enfant et troubles des apprentissages

    • 1st Edition
    • Michèle Mazeau + 1 more
    • French
    L'ouvrageLa vision est à la fois l’un de nos meilleurs outils pour explorer notre environnement et un ressort capital des apprentissages.Souve... masqués, ne se révélant alors que par des troubles des apprentissages, les dysfonctionnements neurovisuels sont complexes et pluriels, pouvant concerner l’attention visuelle ou visuo-spatiale, les stratégies d’exploration visuelle, l’organisation visuo-spatiale du geste ou encore l’interprétation des images rétiniennes (gnosies).Cet ouvrage aborde ainsi en trois temps les liens entre neurovision et troubles des apprentissages chez l’enfant :• l’analyse du message visuel à partir du chiasma optique, la description des voies empruntées et des connexions cérébrales ;• les méthodes d’exploration des fonctions visuelles et neurovisuelles ainsi que l’interprétation des bilans spécifiques ;• l’impact de ces troubles dans les apprentissages scolaires (dyslexies/dysorthog... dyspraxies, dyscalculies), les caractéristiques de leurs manifestations cliniques, ainsi que les principales stratégies d’aide pour un accompagnement efficace des jeunes concernés.Le publicL’objectif est ici de proposer aux psychologues-neurops... médecins (pédiatres et médecins traitants, médecins scolaires, médecins des PCO, des CRTLA, de la MDPH), rééducateurs (orthophonistes, ergothérapeutes, psychomotriciens et orthoptistes), les données qui leur permettront de comprendre et prendre en charge les troubles neurovisuels dans le cadre plus large des troubles neurodéveloppementau... auteursMichèle Mazeau est médecin de rééducation, neuropsychologie de l’enfant (TND : dys et troubles des apprentissages, https://dr-michele-m... Dalens est ophtalmologiste des hôpitaux, centre de rééducation pour déficients visuels et Sessad Victor-Duruy, Clermont-Ferrand.

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