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Elsevier

Books in Life sciences

  • Neuro-Urology Research

    A Comprehensive Overview
    • 1st Edition
    • Anne M.J. Verstegen
    • English
    **Selected for Doody’s Core Titles® 2024 in Urology**Neuro-Urolo... Research: A Comprehensive Overview describes the current status of the neuro-urology field including the latest discoveries, explains in detail some of the neuroscience tools that can be used when studying the neural control of the lower urinary tract, and discusses potential future directions for research. The first section, Neuroscience in Urology Research, reviews neuro-regulators and the important anatomical brain sites. It also provides an overview of voluntary versus reflex micturition control and describes how bladder physiology readout is a useful tool in research. The second section, Fundamental and Translational Neuro-Urology Research, discusses the translational potential of basic research for patients and the impact of neuro-urology research on clinical practice. Chapters in this section provide more insight into pathologies endemic to specific patient populations and areas for treatment development opportunities. The third section, Neurobiological Tools Applied to Neuro-Urology Research, supplements the ‘A Quick Guide to the "Neuroscience Toolbox"’ and introduces research techniques such as RNA sequencing and calcium imaging of neural activity. The fourth and final section, aptly titled Research Directions and Research Opportunities, covers research directions that remain underexplored or have high therapeutic potential. Research in neuro-urology presents a route to understanding how bladder function is controlled and how urinary continence is maintained. This book provides a platform for researchers to initiate collaborations on the many underexplored research topics and to consolidate knowledge, ultimately lending itself to a coordinated and multi-center research approach that will benefit the field.

  • Varieties and Landraces

    Cultural Practices and Traditional Uses
    • 1st Edition
    • Marney Pascoli Cereda + 1 more
    • English
    Varieties and Landraces: Cultural Practices and Traditional Uses, Volume Two in the Underground Starchy Crops of South American Origin series, brings information on the applied level of producing and using starch from a range of plants grown in tropical and subtropical areas of South American origin. The book presents the economic and social importance of these crops that store starch in underground organs. The title also explores bioactive compounds as a way for the valorization of these crops, along with commercial and traditional cultivation in South America (Colombia/Venezuela/... highlands, Mexico, Brazilian savannah and Pantanal, besides the Amazon forest), bringing botanical information, too. Edited by a team of experts with a solid background in starch extraction research, this book is ideal for anyone involved in research and development, as well as anyone in cultivation, quality control and legislation in the field of starch.

  • Glycoside Hydrolases

    Biochemistry, Biophysics, and Biotechnology
    • 1st Edition
    • Arun Goyal + 1 more
    • English
    Glycoside Hydrolases provides a detailed overview of the biochemical, biophysical, and protein engineering properties of glycoside hydrolases, a class of enzymes in growing use across various applications. Here, more than a dozen global experts discuss the structural and catalytic mechanisms of specific glycoside hydrolases, followed by their implications in biotechnological applications of different industrial sectors such as the food and feed industry, paper and pulp industry, the bioenergy sector and the pharmaceutical industry. Authors consider how the application of glycoside hydrolases may boost industrial production of valued products, and the broader environmental and sustainability goals of converting agrowaste into valued products. This book helps researchers and students across industry and academia gain deep knowledge of glycoside hydrolases, to advance new experimental research and applications from biofuel to drug discovery.

  • Lactic Acid Bacteria as Cell Factories

    Synthetic Biology and Metabolic Engineering
    • 1st Edition
    • Didier Montet + 3 more
    • English
    Lactic Acid Bacteria as Cell Factories: Synthetic Biology and Metabolic Engineering describes the most recent developments on the metabolic engineering and synthetic biology of Lactic Acid Bacteria (LAB) for production of biologically active biomolecules (enzymes, organic acids, bacteriocins, bioactive peptides, etc.), recombinant proteins, and their role in bioremediation. The book focuses on synthetic biology and metabolic engineering for the production of biologically active molecules such as bioactive peptides, polysaccharides, vitamins (Riboflavin), enzymes, organic acids (lactic and gamma-aminobutyric acid), flavor and aroma compounds, bacteriocins, recombinant proteins, etc. Individual chapters are devoted to the production of biosurfactants and their applications and the bioremediation of heavy metals by LAB from aquatic environments. Two critical chapters address Genome editing of LAB: opportunities for food, feed and pharmaceuticals and A synthetic biology approach for plasmid DNA and Recombinant protein production. This book will be a valuable resource for those working in biology, biotechnology, biological engineering, chemical engineering, microbiology, food science and technology, genetics and synthetic biology.

  • The Role of Growth Regulators and Phytohormones in Overcoming Environmental Stress

    • 1st Edition
    • Anket Sharma + 4 more
    • English
    The Role of Growth Regulators and Phytohormones in Overcoming Environmental Stress is a comprehensive resource on all major PGRs. These include auxins, cytokinins, jasmonates, polyammines, plant growth promoting rhizobacteria (PGPR), and more. In the last two decades, researchers have explored a lot about the roles of plant growth regulators (PGRs) in boosting the resistance of plants under stress conditions. These PGRs acts as stimulators for various physiological processes by regulating key cell signaling pathways. This title is an essential read for any scientist wanting to understand the latest advances in combatting abiotic stresses using plant growth regulators.In the present era, plants are facing a lot of challenges during their lifecycle, including growth declines due to abiotic stress. The main abiotic stresses threatening plants are water scarcity, salinity, extreme temperatures, heavy metals and pesticides. These stresses directly or indirectly cause toxicity to plants, causing hindrance to their growth and development, and ultimately reduce plant productivity.

  • Epigenetic Cancer Therapy

    • 2nd Edition
    • Steven Gray
    • English
    Epigenetic Cancer Therapy, Second Edition provides a comprehensive discussion of healthy and aberrant epigenetic biology, along with new discoveries to improve our understanding of cancer epigenetics and therapeutics. The book encompasses large-scale intergovernmental initiatives, as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer. Since the publication of the first edition of this book, the field of epigenetics has undergone significant change. New epigenetic therapies have been designed and approved for clinical use. Our knowledge of the plasticity of the epigenome in cancer and disease has expanded dramatically, with increasing evidence linking pollution to epigenetic changes in cancer development. This second edition has been fully updated to address these changes, along with promising therapeutic programs such as CRISPR/Cas9 mediated approaches, CAR-T based therapies, epigenetic priming, histone modifications, and similar, transformative advances across synthetic biology and cellular engineering.

  • Athlete’s Heart

    A Multimodal Approach – From Physiological to Pathological Cardiac Adaptations
    • 1st Edition
    • Antonello D’Andrea + 1 more
    • English
    Athlete's Heart: A Multimodal Approach – From Physiological to Pathological Cardiac Adaptations provides a complete overview of all adaptations of the heart to sport practice by highlighting the different diagnosis between athlete’s heart and pathological remodeling. Written by international experts in the field, chapters discuss ECG findings, echocardiogram data, cardiac magnetic resonance and new forms of multimodality imaging, providing readers with evidence-based guidance on how to differentiate athlete's heart from cardiomyopathies. Athlete's heart is the term given to a constellation of cardiac structural, functional and electrical remodeling that accompanies regular athletic training. Due to the substantial phenotypic overlap between electrical and structural changes observed in the physiological athletic heart remodeling and pathological changes resulted from inherited or acquired cardiomyopathies, distinguishing between adaptive and maladaptive cardiovascular response to exercise is a challenging task.

  • Sulfurtransferases

    Essential Enzymes for Life
    • 1st Edition
    • Noriyuki Nagahara
    • English
    Sulfurtransferases: Essential Enzymes for Life stands as the first comprehensive resource on this increasingly important class of enzymes. Following an introduction to the field from the Editors, each chapter covers a specific sulfurtransferase, including its basic biology and roles in healthy functioning, disease, drug discovery, and other biotechnological applications. The physiological function for each enzyme is considered in depth, along with regulation mechanisms, pharmacological inhibitors, and pathology and conditions related to altered enzymatic activity. Sulfurtransferases discussed include rhodanese, MST, thiosulfate-thiol sulfurtransferase, tRNA uracil 4-sulfurtransferase, thiosulfate-dithiol sulfurtransferases, biotin synthase, cysteine desulfurase, lipoyl synthase, molybdenum cofactor sulfurtransferase, thiazole synthase, molybdopterin synthase sulfurtransferase, molybdopterin synthase, tRNA-uridine 2-sulfurtransferase, tRNA-5-taurinomethyl... 2-sulfurtransferase, tRNA-5-methyluridine (54) 2-sulfurtransferase, and L-aspartate semialdehyde sulfurtransferase, among others. Here, researchers will discover key knowledge and recent advances to bring forward new studies on this increasingly relevant class of enzymes, while clinicians may apply new findings in medical practice.

  • Infectious Diseases

    Smart Study Guide for Medical Students, Residents, and Clinical Providers
    • 1st Edition
    • Saif ul Islam
    • English
    Infectious Diseases: Smart Study Guide for Medical Students, Residents, Physicians and Clinical Pharmacists attempts to consolidate knowledge and information into a step-by-step process that would be easy to understand, remember, and apply in a clinical setting. High-yield information presented in this book is necessary for medical students and residents. This book has provided information for all disciplines working in infectious diseases, whether students, residents, physicians, pharmacists, or nurses. The book is organized for quick and easy to retrieve information for all professionals.

  • Medicinal Chemistry of Anticancer Drugs

    • 3rd Edition
    • Carmen Avendaño + 1 more
    • English
    This third edition of Medicinal Chemistry of Anticancer Drugs, provides an updated resource for students and researchers from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. This new edition includes updated sections on the hot topic of cancer immunotherapy, cancer polypharmacology, multitargeted cancer therapy, medicinal chemistry of cancer diagnosis, theranostic anticancer agents, and pre-mRNA processing in cancer. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a unique and valuable perspective from the point of view of medicinal chemistry and drug design. It will be useful to undergraduate and postgraduate students of medicinal chemistry, pharmacology, biological chemistry, pharmacy and other health sciences. Researchers and practitioners will find a comprehensive treatment of the topic and a large number of references to reviews and the primary literature.

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