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Elsevier

Books in Life sciences

  • Innovations for Sustainable Agriculture

    From Lab to Farm to Table
    • 1st Edition
    • Katarzyna Chojnacka + 1 more
    • English
    Mixed crop-livestock systems offer promising strategies for sustainable farming. Innovations for Sustainable Agriculture: From Lab to Farm to Table details solutions for mitigating agricultural waste, such as carbon emissions and chemical runoff, and creating a circular economy on mixed farms. In addition to covering potential solutions, the book will analyze the effectiveness of each strategy in protecting the environment from harm. Notable topics covered include manure management, agricultural waste valorization, wastewater and resource recovery, and even dairy cow feed for lowering methane production.While the book is based primarily on the climates and farming systems of Europe, the climactic diversity of the continent will make this a useful resource for many other parts of the world with similar climates, including North America and portions of South America, Asia, and Oceana. Innovations for Sustainable Agriculture: From Lab to Farm to Table offers practical strategies and solutions to readers and will benefit audience members ranging from students and researchers to farmers and agricultural stakeholders.

  • Protein Serine/Threonine Kinases in Neurodegenerative Disorders

    • 1st Edition
    • Heba Mohamed Mansour + 1 more
    • English
    Protein Serine/Threonine Kinases in Neurodegenerative Disorders provides a comprehensive overview of protein serine/threonine kinases (STKs) in health and disease. It also discusses protein kinase inhibitors and their potential role in modulating and treating neurodegenerative diseases. This book begins with an introduction to protein kinases and inhibitors, followed by detailed discussions on different types of kinases, including protein kinase C (PKC), AMP-activated protein kinase (AMPK), death-associated protein kinase 1 (DAPK1), cyclin-dependent kinases (CDKs), glycogen synthase kinases (GSKs), Rho-associated protein kinase (ROCK), microtubule affinity regulating kinases (MARKs), mammalian target of rapamycin (mTOR), leucine-rich repeat kinase 2 (LRRK2), PTEN-induced kinase 1 (PINK1), and dual-specificity tyrosine phosphorylation-regu... kinase (DYRK), and their roles in neurodegenerative disease, potential inhibitors, and therapeutic mechanisms.This book features 23 chapters written by renowned experts in the field of kinases. It explores novel targets modulated by protein kinases, including noncoding RNAs (ncRNAs) and mitogen-activated protein kinases (MAPKs) activated by tyrosine receptor kinases, and their roles in neurodegeneration. It also discusses the nexus between glycogen synthase kinases (GSKs) and glucagon-like peptide-1 receptor agonists (GLP-1RAs) and their role of metabolic regulation in neurodegeneration. The modulatory effects of protein kinase B (PKB/AKT) pathways in various neurodegenerative disorders, particularly Parkinson’s disease, are also examined. This book sheds light on bioactive compounds from natural products that target kinases. This book explains the role of different kinases in various pathogenic pathways and mechanisms involved in neurodegeneration, including regulated cell death, autophagy, synaptic dysfunction, and neuroinflammation. It also discusses splicing kinases in regulating splicing factor phosphorylation and details how aberrant kinase activity leads to splicing defects that contribute to neurodegenerative pathologies. This book emphasizes bridging laboratory research with clinical applications, focusing on translational opportunities. It includes insights from FDA regulatory experts on therapeutic applications and safety considerations of targeting kinases, highlighting the importance of balancing efficacy and safety, particularly in relation to drug-induced liver injury associated with kinase inhibitors. Finally, this book discusses the obstacles and opportunities for the potential repositioning of protein kinase inhibitors in neurodegenerative disorders

  • Advances in Transfusion Medicine

    A Practical Handbook
    • 1st Edition
    • Parmatma Prasad Tripathi
    • English
    Advances in Transfusion Medicine: A Practical Handbook presents a detailed overview of transfusion medicine, beginning with blood components and derivatives therapy, including RBC, platelet, and plasma transfusions, as well as hematopoietic stem cell therapy. The book addresses patient blood management, focusing on practical applications and specific considerations in various populations. Safety practices in transfusion, including blood donation strategies and reactions are also covered. In addition, emerging therapies and technologies, such as artificial red blood cells and gene therapy are explored alongside global health challenges related to blood safety and shortages.The role of immunohematology and genomics is highlighted, along with cellular therapy applications, ethical considerations, and a discussion on pediatric transfusions and guidelines for managing transfusions in children. Miscellaneous topics like emerging infections and pathogen reduction technologies complete the overview, emphasizing current practices and future directions in the field.

  • Immunotherapies for Neurological Disorders

    Unlocking the Brain's Defenses
    • 1st Edition
    • Akash Gautam + 1 more
    • English
    Immunotherapies for Neurological Disorders: Unlocking the Brain's Defenses explores the complex intersection of both the immune and nervous systems and neurological disorders. This comprehensive guide details the vital role of immunology in understanding conditions from Alzheimer's and Parkinson's to autoimmune diseases like multiple sclerosis and Guillain-Barré syndrome. Each chapter reviews strategies, including the use of antibodies, recombinant proteins, and cutting-edge vaccine approaches to modulate immune responses in the brain. Readers will be presented with the therapeutic potential of immune cells, gene therapy, and RNA interference in combating these debilitating disorders, while also examining the role of nanotechnology in enhancing treatment efficacy.Aimed at neurologists, immunologists, researchers, and students alike, this book serves as an essential resource for the latest advancements in neurological disease treatment.

  • Insights and Implications of Pseudo Esterase Activity of Human Serum Albumin in Diabetic Kidney Disease

    • 1st Edition
    • Dibyajyoti Banerjee
    • English
    Insights and Implications of Pseudo Esterase Activity of Human Serum Albumin in Diabetic Kidney Disease provides a comprehensive exploration of diabetic nephropathy, emphasizing the critical need for early detection methods prior to the onset of microalbuminuria. The book's primary focus is on the study of pseudoesterase activity in urinary albumin and other proteins as a potential biomarker for early diagnosis of diabetic kidney disease. This resource bridges a significant gap in current literature by providing an in-depth analysis of how this enzymatic activity can inform the classification and management of diabetic nephropathy.Chapters cover foundational knowledge of diabetes and its complications, the mechanisms of diabetic nephropathy, and detailed discussions on human serum albumin and its enzymatic activities. Each chapter covers the biochemical characterization of pseudoesterase activity, methods for its detection, and the significance of urinary proteomic profiling. Final chapters highlight future research opportunities and the potential for developing point-of-care testing tools, positioning this work as a critical resource for advancing the field of diabetic kidney disease research and clinical practice.

  • Advancements in Personalized Cellular Immunotherapy

    A Comprehensive Guide to Cancer Treatment
    • 1st Edition
    • Arun Kumar Singh + 3 more
    • English
    Advancements in Personalized Cellular Immunotherapy: A Comprehensive Guide to Cancer Treatment is an authoritative guide that delves into the foundational principles, recent advancements, and clinical applications of this innovative treatment approach, aiming to bridge the gap between research and clinical practice. It offers a thorough analysis of the mechanisms of action, therapeutic efficacy, and safety profiles of various cellular immunotherapy modalities, enabling clinicians to make well-informed treatment decisions and optimize patient outcomes. The book promotes interdisciplinary collaboration by bringing together experts from oncology, immunology, molecular biology, and translational medicine. Through detailed case studies, clinical guidelines, and practical insights, it provides healthcare professionals with the knowledge and tools needed to effectively incorporate cellular immunotherapy into standard oncology practice. Additionally, the book addresses key challenges and future directions in the field, such as strategies to enhance treatment efficacy, overcome resistance mechanisms, and broaden the accessibility of cellular immunotherapy to more patients. Advancements in Personalized Cellular Immunotherapy: A Comprehensive Guide to Cancer Treatment aims to educate and empower healthcare professionals, fostering continued innovation and collaboration to improve cancer care and patient outcomes.

  • Advances in Virus Research

    • 1st Edition
    • Volume 125
    • English
    Advances in Virus Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Advances in Rice Research for Abiotic Stress Tolerance

    • 2nd Edition
    • Mirza Hasanuzzaman + 3 more
    • English
    Rice production is increasingly challenged by abiotic stresses—such as extreme temperatures, drought, salinity, and flooding—which undermine both yield and grain quality. Tackling these constraints is crucial for global food security and depends on improved farming practices, the development of resilient cultivars, and the adoption of emerging technologies.Advance... of Rice Research for Abiotic Stress Tolerance, Second Edition, integrates new research across multiple fronts, including advances in genetic markers, modern breeding approaches, and biotechnological tools. It updates readers on cutting‑edge methodologies to mitigate climate‑related impacts and introduces expanded content on microbiome‑driven resilience, sustainable cultivation and intensification techniques, and genome editing applications that enhance crop performance under environmental stress. By capturing current global trends alongside practical solutions in rice science, the volume serves researchers, educators, and professionals working across agronomy, plant physiology, molecular biology, soil science, and related disciplines.

  • Cell Death Part C

    • 1st Edition
    • Volume 208
    • English
    Cell Death: Part C, Volume 208 continues the comprehensive exploration of cellular mechanisms governing the fate of cells in health and disease. This volume delves deep into the molecular pathways, regulatory networks, and biological consequences of various cell death modalities, including apoptosis, necrosis, autophagy, ferroptosis, pyroptosis, and other emerging forms.

  • Ethnoscience

    Insights into Nutrition and Cultural Foundations
    • 1st Edition
    • Tanmay Sarkar + 4 more
    • English
    Ethnoscience: Insights into Nutrition and Cultural Foundations is the first book in the series “Culinary Synergies: Exploring Nutrition and Science in Gastronomy”, a five-book exploration into food education, innovation, and preservation. The series encompasses everything from flavor chemistry and sensory science to the role of micro- and macronutrients in traditional and culturally specific diets. It integrates scientific understanding with the latest research in nutrition and considers the environmental implications of specific food choices and the role of food and culture within gastronomy.Divided into four sections, Ethnoscience begins with an introduction to the discovery of food through nutrition and cultural identity, discussing modern technological advances such as machine learning, digital tools, and sustainability. It then moves into the culinary traditions of Southeast Asia, where food diversity and ingredient preparation's influence on nutritional value are discussed. Section two highlights Southern Europe, focusing on foraging and the health benefits of fermented foods and more. Finally, section three introduces sustainable and indigenous farming practices in North Africa, along with healing herbs, their medicinal properties, and much more. Each section includes case studies highlighting nutrition, innovation, and health.

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