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Elsevier

Books in Life sciences

  • Exploring Nanocarriers in Breast Cancer Management

    • 1st Edition
    • Amarjitsing Rajput + 3 more
    • English
    Exploring Nanocarriers in Breast Cancer Management comprehensively delves into the realm of nanocarrier systems, which have shown immense potential in the management of breast cancer. The scope of this book encompasses a thorough exploration of various nanocarrier systems, including, amongst others, liposomes, niosomes, and microneedles. It highlights recent advancements in these systems and their promising results in breast cancer treatment. Additionally, the book addresses the crucial aspects of toxicity and regulatory considerations associated with nanocarriers. It aims to provide a foundational understanding of nanocarriers, their unique features, and their significant role in breast cancer management.As breast cancer remains one of the most prevalent forms of cancer today, with no definitive cure currently available, this book is an essential resource for researchers, healthcare professionals, and anyone interested in cutting-edge developments in breast cancer treatment.

  • Human Histology

    A Text and Atlas for Physicians and Scientists
    • 2nd Edition
    • Bertalan Dudas
    • English
    Human Histology: A Text and Atlas for Physicians and Scientists, Second Edition offers full-page, low-magnification photomicrographs for organs and tissues surrounded by high-power images of the same sample. Each specimen is followed by a compact and simple-to-read description of the structures identified on the micrographs, offering a clear, visual understanding. In addition to 300 outstanding images, this new edition includes schematics of each organ for a more detailed representation, making it easier to learn. This is an invaluable resource for every clinical researcher and pathologist in need of accessible, relatively simple, but detailed information on normal histology in different organs systems.

  • Practice of Neuroanesthesia in Resource Limited Countries

    • 1st Edition
    • Hemanshu Prabhakar + 2 more
    • English
    Practice of Neuroanesthesia in Resource Limited Countries reviews the critical challenges and innovative solutions in delivering neuroanesthesia care within low- and middle-income countries (LMICs). As these regions grapple with a high prevalence of neurological disorders and limited resources, this book delves into the core principles of neuroanesthesia, emphasizing safety, efficacy, and essential monitoring techniques. It addresses the availability of equipment and medications, offering practical alternatives tailored to resource constraints. Special considerations for pediatric populations, trauma management in emergencies, and regional anesthesia techniques are thoroughly examined. This book also emphasizes the importance of postoperative care and neurocritical support, highlighting strategies for effective recovery in resource-limited settings. Furthermore, it advocates for building local capacity through training, education, and collaborative efforts, underscoring the role of simulation and remote learning. With contributions from authors across various LMICs, this comprehensive resource aims to enhance the practice of neuroanesthesia and improve patient outcomes in regions where healthcare systems face significant challenges.

  • Agroforestry Solutions for Soil Restoration and Sustainable Land Management

    • 1st Edition
    • Ram Yadav + 3 more
    • English
    Agroforestry Solutions for Soil Restoration and Sustainable Land Management, a volume in the Agricultural Soil Degradation and Restoration series, offers a rigorous, cross-disciplinary assessment of tree–crop integration as a driver of resilient landscapes and livelihoods around the world. Rooted in edaphic science, agroecology, and development studies, it analyzes contemporary pressures, evaluates viable interventions, and maps forward-looking research avenues. By blending empirical evidence with policy considerations, it demonstrates how diversified, multi-species systems enhance nutrient balance, water regulation, carbon dynamics, and biodiversity, while supporting stable incomes and high-quality food.This essential resource for researchers, educators, and practitioners covers design principles, deployment pathways, governance, extension strategies, and economic analysis, complemented by real-world case studies. Readers will find robust study designs, interoperable data assets, and reproducible workflows that enable scalable decision-making and monitoring. The narrative emphasizes UNCCD targets and climate-smart land use, with clear implications for sustainable intensification and ecosystem stewardship.

  • MRI of Brain Physiology

    Novel Methods and Clinical Applications
    • 1st Edition
    • Audrey P. Fan + 1 more
    • English
    MRI of Brain Physiology: Novel MRI Methods and Clinical Applications delves into the intricate world of brain physiology, focusing on the latest magnetic resonance imaging (MRI) methods and their clinical applications. Designed for biomedical engineers, technologists, radiologists, neurologists, neurosurgeons, and clinical researchers, this resource bridges the gap between advanced imaging techniques and practical clinical use. It covers a wide spectrum of cerebral physiology, from microvascular and macrovascular dynamics to cerebrovascular reserve, neurovascular coupling, and cerebrospinal fluid pathways. Each of the core chapters has a tripartite structure: physiology (concepts of the physiological processes), imaging techniques, and clinical applications. Readers will find detailed discussions on emerging MRI methods, including dynamic contrast, arterial spin labeling, and quantitative BOLD models. The book also addresses the functional impact of physiological changes on tissue microstructure and integrity, offering insights into multiparametric relaxation mapping and quantitative susceptibility mapping. Uniquely, this book gives a comparative approach to different brain physiological MRI methods, highlighting their strengths, limitations, and reliability.

  • An Illustrated Guide to Cancer Biology

    • 1st Edition
    • Tomas Koltai + 1 more
    • English
    An Illustrated Guide to Cancer Biology offers a comprehensive exploration of the fundamentals of oncological molecular biology and provides valuable insights into topics such as cancer cell migration, chemotherapeutic drug mechanisms, and the roles of RNA in cancer. With 33 chapters covering a wide array of subjects, including the Hanahan and Weinberg hallmarks of cancer, tumor heterogeneity, and hormone-dependent cancer, this guide serves as an indispensable resource for researchers, students, and practicing oncologists in medicine, oncology, and biochemistry alike. This book stands out not only for its comprehensive coverage of diverse topics but also for its unique approach.With over 400 figures strategically interspersed throughout the text, this book offers readers a visually engaging journey through the intricacies of cancer biology. These illustrations, ranging from molecular pathways to cellular interactions, make navigating topics like chemotherapeutic drug mechanisms and tumor heterogeneity more accessible. Additionally, the inclusion of sections on repurposing drugs, tumor kinetics, and epigenetics further aids in a deep understanding of cancer biology.

  • Moving Toward Nonanimal Approaches in Medical Research and Testing

    • 1st Edition
    • Gail A. Van Norman + 1 more
    • English
    Moving Toward Nonanimal Approaches in Medical Research and Testing pioneers a single-source guide for researchers regarding nonanimal research tools and methodologies and their many advantages and applications in place of animals. This book is presented in three parts: historical, ethical, legislative, and scientific contexts on the need to shift away from animal-based research and testing; the latest advances in nonanimal tools and methods for biomedical research and testing of human therapeutics and other compounds, including microphysiological systems, bioprinting, biobanks, and artificial intelligence; and achieving a practical shift toward these powerful approaches, including advocacy for legal, regulatory, and policy change, securing funding for nonanimal studies, and how to overcome bias against nonanimal methods. This book, primarily directed to researchers in biomedicine, human medical therapeutics, and toxicology, will also appeal to researchers in industry, providing overview and insights about the latest applications of nonanimal research tools and methods for product development and testing. Clinicians who wish to understand the reliability of testing therapeutics with nonanimal versus animal methods, as well as advocacy groups seeking an up-to-date understanding of ethical, economic, political, and scientific considerations in moving toward nonanimal approaches, will also find significant value in this text. Finally, legislators and those involved in regulatory review and oversight will benefit from this single comprehensive source for developing a basic understanding of nonanimal research and human safety.

  • Cardiometabolic Dynamics

    A Deep Dive into Health and Disease
    • 1st Edition
    • Yihua Bei + 1 more
    • English
    Cardiometabolic Dynamics: A Deep Dive into Health and Disease explores the intricate relationship between metabolic health and cardiovascular diseases, illuminating how cellular and molecular mechanisms contribute to metabolic dysregulation. The book delves into the ways metabolic pathologies act as precursors to cardiovascular conditions, including hypertension, atherosclerosis, cardiomyopathy, and heart failure. With a focus on healthy cardiometabolic dynamics, it underscores the crucial role they play in sustaining cardiovascular wellness, offering a comprehensive perspective on the intersection of metabolism and heart health.The book further examines the influence of lifestyle factors, such as diet and exercise on cardiovascular metabolism and highlights emerging technologies like omics, genetic engineering, and wearable devices to advance research, diagnosis, and treatment.

  • Proteostasis and Cancer

    • 1st Edition
    • Buddhi Prakash Jain
    • English
    Proteostasis and Cancer explores the intricate mechanisms of protein homeostasis and their critical roles in cancer progression and therapeutics. The book delves into the mechanisms that control proteins inside the cell to preserve the health of the cellular proteome and the organism itself. It covers key topics such as post-translational modifications, protein folding, proteolysis, and the unfolded protein response (UPR), with a specific focus on their roles in cancer. Detailed discussions on molecular chaperones, the ubiquitin-proteasome system, and autophagy pathways offer valuable insights into how these processes contribute to cancer progression and how they can be targeted for therapeutic interventions.With clear explanations and well-labeled diagrams, the book makes complex concepts accessible to students and researchers alike. It also addresses the clinical implications of proteostasis in cancer, providing a foundation for developing innovative, therapeutic strategies. The book's multidisciplinary approach, combining insights from biochemistry, cancer biology, and medical sciences make it an essential resource for anyone seeking to understand the role of proteostasis in cancer.

  • A Modern Atlas for Implantable Devices of the Spine, Brain, and Nerve

    For Pain, Movement Disorders, and Nerve Dysfunction
    • 1st Edition
    • Timothy R. Deer + 1 more
    • English
    A Modern Atlas for Implantable Devices of the Spine, Brain, and Nerve: For Pain, Movement Disorders, and Nerve Dysfunction is an essential resource for healthcare professionals and researchers working in neuromodulation. This groundbreaking text focuses on the latest advancements in implantable technologies, exploring innovative techniques, frequencies, and neural targets that have revolutionized patient care. Covering a diverse range of conditions related to pain, movement disorders, and nerve dysfunction, the atlas provides a detailed overview of spinal, brain, and peripheral nerve procedures. It combines anatomical insights with clinical best practices to help professionals achieve enhanced outcomes in complex medical scenarios.In addition to introducing cutting-edge devices, the book delves into procedures like spinal cord stimulation and dorsal root ganglion modulation, offering a roadmap for navigating intricate anatomical and procedural landscapes. The atlas includes valuable sections on sacral nerve modulation and peripheral nerve stimulation, ensuring comprehensive coverage of neuromodulation's expanding possibilities. By bridging theoretical knowledge with practical application, this resource equips practitioners with the tools needed to address diverse patient challenges effectively.

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