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Elsevier

Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

  • The Chemistry of Pyrroles

    Organic Chemistry: A Series of Monographs, Vol. 34
    • 1st Edition
    • R. Alan Jones + 1 more
    • Alfred T. Blomquist + 1 more
    • English
    The Chemistry of Pyrroles, Volume 34 aims to provide a comprehensive survey of the synthesis of simple pyrroles and to present, wherever possible, a mechanistic and theoretical rationale for the multitude of reactions known for pyrroles. The book discusses the structure and reactivity of pyrrole; the synthesis of the pyrrole ring; and the electrophilic substitution of the pyrrole ring. The text also describes the oxidation and reduction of the pyrrole ring; the rearrangement and addition reactions; and the ketones, aldehydes, and carboxylic acid derivatives of pyrrole. Alkylpyrroles and related compounds; hydroxy- and aminopyrroles and related compounds; and azafulvenes are also considered. The book further tackles the physico-organic properties of pyrrole. Chemists and researchers of pyrrole chemistry will find the text invaluable.

  • Fundamentals of Energy Dispersive X-Ray Analysis

    Butterworths Monographs in Materials
    • 1st Edition
    • John C. Russ
    • M. Ashby Frs + 2 more
    • English
    Fundamentals of Energy Dispersive X-ray Analysis provides an introduction to the fundamental principles of dispersive X-ray analysis. It presents descriptions, equations, and graphs to enable the users of these techniques to develop an intuitive and conceptual image of the physical processes involved in the generation and detection of X-rays. The book begins with a discussion of X-ray detection and measurement, which is accomplished by one of two types of X-ray spectrometer: energy dispersive or wavelength dispersive. The emphasis is on energy dispersive spectrometers, given their rather widespread use compared to the wavelength dispersive type. This is followed by separate chapters on techniques such as X-ray absorption; spectrum processing; and elimination of spectrum background produced by electron excitation. Subsequent chapters cover X-ray fluorescence; the use of regression models; hardware for X-ray fluorescence analysis; scattering, background, and trace element analysis; and methods for producing inner shell excitation of atoms in a sample of interest. The final chapter deals with applications of X-ray analysis.

  • Advances in Magnetic Resonance

    Volume 1
    • 1st Edition
    • John S. Waugh
    • English
    Advances in Magnetic Resonance, Volume 1, discusses developments in various areas of magnetic resonance. The subject matter ranges from original theoretical contributions through syntheses of points of view toward series of phenomena to critical and painstaking tabulations of experimental data. The book contains six chapters and begins with a discussion of the theory of relaxation processes. This is followed by separate chapters on the development of magnetic resonance techniques for studying rate processes in chemistry and the application of these techniques to various problems; the geometrical and electronic structures of paramagnetic molecules and complex ions; and various theoretical formulations of spin-spin coupling. Subsequent chapters deal with geminal and vicinal proton-proton coupling constants from values reported in the literature; and electron spin resonance of radical ions. This serial publication was conceived with the insiders as well as the interested outsiders in mind. The editor hopes that readers who consult this book for a particular article will in some measure profit by being exposed to some of the other contributions.

  • Ab Initio Valence Calculations in Chemistry

    • 1st Edition
    • D. B. Cook
    • English
    Ab Initio Valence Calculations in Chemistry describes the theory and practice of ab initio valence calculations in chemistry and applies the ideas to a specific example, linear BeH2. Topics covered include the Schrödinger equation and the orbital approximation to atomic orbitals; molecular orbital and valence bond methods; practical molecular wave functions; and molecular integrals. Open shell systems, molecular symmetry, and localized descriptions of electronic structure are also discussed. This book is comprised of 13 chapters and begins by introducing the reader to the use of the Schrödinger equation to solve the electronic structure of molecular systems. This discussion is followed by two chapters that describe the chemical and mathematical nature of orbital theories in quantum chemistry. Two general ways of using chemical and physical information in looking for approximate solutions of the Schrödinger equation are highlighted: model approximations and numerical approximations. Attention then turns to atomic orbitals as the basis of a description of molecular electronic structure; practical molecular wave functions; and a general strategy for performing molecular valence calculations. The final chapter examines the nature of the valence electronic structure by using invariance with respect to transformations among the occupied molecular orbitals and among the atomic orbitals. This text will be of interest to students and practitioners of chemistry, biochemistry, and quantum mechanics.

  • Mechanisms of Chemical Carcinogenesis

    • 1st Edition
    • D. E. Hathway
    • English
    Mechanisms of Chemical Carcinogenesis provides information pertinent to the fundamental mechanisms of chemical carcinogenesis. This book surveys the interactions of chemical carcinogens with native DNA, the activation of normal cellular sequences, and the transforming role of the activated genes. Organized into seven chapters, this book begins with an overview of the relationship between the incidence of lung cancer and the frequency and duration of cigarette smoking. This text then examines the concept that carcinogens may require metabolic activation before they initiate carcinogenesis. Other chapters consider the structure of the nucleoside adducts resulting from the hydrolysis of salmon-sperm DNA and rat-liver ribosomal RNA. This book discusses as well the persistence of nucleoside analogues in target-tissue nucleic acid. The final chapter deals with mutational theory. This book is a valuable resource for workers involved with cancer research, toxicology, and molecular biology. Specialists in drug development, industrial hygiene and occupational medicine will also find this book useful.

  • Pharmaceutical and Biomedical Applications of Liquid Chromatography

    • 1st Edition
    • Volume 1
    • W.J. Lough + 2 more
    • English
    This volume reflects the changes that have taken place in the pharmaceutical industry over the last ten years, most notably the increased importance attached to the question of chirality, the growing influence of biotechnology and the need for more rigorous documentation and validation of analytical methods and procedures.The first part of this book deals with the application of new technology to pharmaceutical and biomedical analysis, reflecting the present needs for increased speed, sensitivity and selectivity in the analysis of drugs. The second chapter provides an overview of capillary electophoresis, which represents one of the most inportant analytical developments to impact directly on pharmaceutical development in recent years. Although not a chromatographic technique, capillary electrophoresis was considered too important to be ignored.Over the last 25 years, liquid chromatography has grown into a mature analytical technique and many of the fundamental issues concerned with retention and separation are well defined. The practitioners of modern liquid chromatography spend as much time in the development of techniques for sampling handling and automation as they do in the development of the separation. Therefore, Part Two of this book describes some of the recent advances in the areas of sample handling and the isolation of compounds from biological samples, including solid phase extraction, restricted access media for direct injection, coupled column technology and microdialysis. Similarily, Part Three contains two chapters concerned with liquid chromatographic methods for the isolation of drug substances, peptides and proteins from other complex media.The pharmaceutical industry and the process of drug development are highly regulated and the increasing importance that the regulatory authorities attach to validation has had a significant impact on the analytical techniques used for the analysis of drugs. Although this has increased the workload of analysts in the pharmaceutical industry, it has also improved the quality of analytical methods used in the support of investigational and new drug applications as well as the quality of methods published more recently in the literature. Consequently, Part Four of this volume describes approaches to the optimization and validation of liquid chromatography methods for the analysis of drugs in the bulk form, in pharmaceutical formulations and biological fluids.

  • High Resolution Spectroscopy

    • 1st Edition
    • J. Michael Hollas
    • English
    High Resolution Spectroscopy discusses the underlying concepts in the different branches of spectroscopy, especially in high resolution spectroscopy. The coverage of the book includes basic principles such as the quantization of energy, as well as the interaction of electromagnetic radiation with atoms and molecules; general experimental methods and features of instrumentation; and microwave, millimeter wave, and lamb dip spectroscopy. Also covered in the book are subjects such as the principles behind rotational spectroscopy; diatomic and polyatomic molecules in vibrational spectroscopy; and the electronic spectroscopy of atoms, as well as diatomic and polyatomic molecules. The text is recommended for engineers and physicists who would like to know more about the concepts, theories, methods, and instrumentation related to spectroscopy, particularly in the field of high resolution spectroscopy.

  • Organic Chemistry in Action

    The Design of Organic Synthesis
    • 1st Edition
    • Volume 41
    • F. Serratosa
    • English
    Contrary to all other books in the field of organic synthesis, this volume combines Corey's methodology, which is based on the concept of synthon and retrosynthetic analysis, with Evans' methodology based on the `Lapworth model' of alternating polarities. Using this approach, the formation of carbon-carbon bonds and the manipulation of functional groups are treated together, whereas the stereochemical aspects are considered separately. Emphasis is laid on the importance of rigid structures, whether in the starting materials, the synthetic intermediates or the transition states, as a means of controlling the stereochemistry of the organic compounds.Enclosed with the book is a copy of a miniprogram (CHAOS) for an IBM PC, or fully compatible computers, which is an interactive program, affording the beginner a fast and easy way of learning, exploring and looking for new synthetic schemes of molecules of moderate complexity. As a textbook on organic synthesis, this volume will be of immense value at university level.

  • Natural Products Chemistry

    Volume 2
    • 1st Edition
    • Koji Nakanishi + 2 more
    • English
    Natural Products Chemistry, Volume 2 covers the introductory survey, history, structure, synthesis, reactions, and biosynthesis of natural products such as the fatty acid derivatives and related compounds; sugars (carbohydrates); carboaromatic and related compounds; alkaloids; and non-alkaloidal nitrogen compounds. The text also describes the aspects of natural products photochemistry.

  • Annual Reports in Organic Synthesis 1995

    • 1st Edition
    • Volume 1995
    • Philip M. Weintraub
    • English
    This handy reference tool is an organized annual review of synthetically useful information. It abstracts synthetic reactions from the major chemistry journals of the past year and includes reactions and methods thatare new and reasonably general. The reactions are presented in a convenient pictorial format designed for rapid visual retrieval of information.The Journal of the American Chemical Society has aptly described this publication as an"aid to the harassed organic chemist who cannot keep up with the never-diminishing stream of new primary literature"and hails it"an outstandingly good buy."

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