Synthesis of Azetidines from Imines by Cycloaddition Reactions
- 1st Edition - January 10, 2023
- Latest edition
- Author: Navjeet Kaur
- Language: English
Synthesis of Azetidines from Imines by Cycloaddition Reactions presents several methodologies for the synthesis of azetidines from imines by cycloaddition reactions… Read more
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Description
Description
Synthesis of Azetidines from Imines by Cycloaddition Reactions presents several methodologies for the synthesis of azetidines from imines by cycloaddition reactions. The azetidines, known as important contribution of science to humanity, are important organic compounds that have occupied a basic position in the pharmaceutical chemistry for over a hundred years because of their biological activities. They are the fundamental skeleton of several antibiotics, probiotics and alkaloids. The synthesis of azetidines is a constant challenge for medicinal chemists, hence this book comprehensively describes azetidine ring synthesis.
With this book, readers will be able to quickly assess possible synthetic approaches and evaluate whether preparation of a four-membered nitrogen containing ring is reasonable.
Key features
Key features
- Highlights cycloaddition reactions of imines
- Covers the synthesis of azetidines
Readership
Readership
Table of contents
Table of contents
Chapter-1: Synthesis of azetidines from imines
1.1 Introduction
1.2 Synthesis of azetidines from imines
1.3 Synthesis of azetidines from imines and carbon monoxide
1.4 Synthesis of azetidines from haloimine compounds
References
Chapter-2: Synthesis of azetidines by cycloaddition of imines to alkenes
2.2 Synthesis of azetidines by cycloaddition of imines to alkenes
2.3 Synthesis of azetidines by LDA-assisted cycloaddition of imines to alkenes
2.4 Synthesis of azetidines by lithium-assisted cycloaddition of imines to alkenes
References
Chapter-3: Synthesis of azetidines by metal-catalyzed cycloaddition of imines to alkenes
3.2 Synthesis of azetidines by metal vinylidene-catalyzed cycloaddition of imines to alkenes
3.3 Synthesis of azetidines by metal-catalyzed cycloaddition of imines to alkenes
3.4 Synthesis of azetidines by titanium-catalyzed cycloaddition of imines to alkenes
References
Chapter-4:
Synthesis of azetidines by cycloaddition of imines to ketenes-I4.1 Introduction
4.2 Synthesis of azetidines by cycloaddition of imines to ketenes
References
Chapter-5: Synthesis of azetidines by cycloaddition of imines to ketenes-II
5.2 Synthesis of azetidines by ferrocene-assisted cycloaddition of imines to ketenes
5.3 Synthesis of azetidines by N-heterocyclic carbene-assisted cycloaddition of imines to ketenes
5.4 Synthesis of azetidines by metal-assisted cycloaddition of imines to ketenes
5.5 Synthesis of azetidines by polymer-supported reagent-assisted cycloaddition of imines to ketenes
5.6 Synthesis of azetidines by triethylamine-assisted cycloaddition of imines to ketenes
References
Chapter-6: Synthesis of azetidines by cycloaddition of imines to carbonyl compounds
6.2 Synthesis of azetidines by intramolecular cycloaddition of imine to carbonyl moiety using NaHMDS
6.3 Synthesis of azetidines by cycloaddition of imines to carbonyl compounds using zinc reagents
6.4 Miscellaneous synthesis of azetidines by cycloaddition of imines to carbonyl compounds
References
Chapter-7: Synthesis of azetidines by cycloaddition of imines to acetyl chloride moiety
7.2 Synthesis of azetidines by cycloaddition of imines to acetyl chloride moieties
7.3 Synthesis of azetidines by cycloaddition of imines to acetoxyacetyl chlorides
7.4 Synthesis of azetidines by cycloaddition of imines to methoxyacetyl chlorides
7.5 Synthesis of azetidines by cycloaddition of imines to oxazolidinylacetyl chlorides
7.6 Synthesis of azetidines by cycloaddition of imines to proline acid chlorides
References
Chapter-8: Synthesis of azetidines by cycloaddition of imines to aromatic acetyl chloride moiety
8.2 Synthesis of azetidines by cycloaddition of imines to benzyloxyacetyl chlorides
8.3 Synthesis of azetidines by cycloaddition of imines to phenoxyacetyl chlorides
8.4 Synthesis of azetidines by cycloaddition of imines to phenylacetyl chlorides
References
Chapter-9: Synthesis of azetidines by cycloaddition of imines to chloroacetyl chloride-I
9.2 Synthesis of azetidines by cycloaddition of imines to chloroacetyl chloride
9.3 Synthesis of azetidines by cycloaddition of imines to chloroacetyl chloride using triethylamine and dioxane
References
Chapter-10: Synthesis of azetidines by cycloaddition of imines to chloroacetyl chloride-II
10.2 Synthesis of azetidines by cycloaddition of imines to chloroacetyl chloride using triethylamine
References
Product details
Product details
- Edition: 1
- Latest edition
- Published: January 10, 2023
- Language: English
About the author
About the author
NK
Navjeet Kaur
Dr. Navjeet Kaur, Ph.D. (Chemistry, Banasthali Vidyapith, 2014) is currently an Associate Professor in the Department of Chemistry and Division of Research & Development at Lovely Professional University, Punjab. She specializes in organic synthetic and medicinal chemistry, with a focus on heterocyclic compound synthesis. With 14 years of teaching and research experience, she has guided five Ph.D. scholars and numerous MSc students, and has published over 200 research papers, reviews, books, and chapters. She is the author of nineteen books with leading publishers including CRC Press, Elsevier, and Springer Nature.
Dr. Kaur has consistently ranked among the World’s Top 2% Scientists in subject-wise analyses by Stanford University (2018–2025). She has received awards such as the Prof. G. L. Telesara Award and Best Paper Presentation Award, and has served as Editor-in-Chief of Advanced Chemicobiology Research. Beyond academia, she has contributed to rural development initiatives through NSS and UBA, and holds a Sikh Missionary certification.
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