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System Vaccinology

The History, the Translational Challenges and the Future

  • 1st Edition - August 20, 2022
  • Latest edition
  • Editor: Vijay Kumar Prajapati
  • Language: English

Emergence of new and deadly infectious diseases is significantly deteriorating the human health. Development of vaccine by the scientist has become an important weapon to co… Read more

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Description

Emergence of new and deadly infectious diseases is significantly deteriorating the human health. Development of vaccine by the scientist has become an important weapon to control the spread of infectious diseases as well as to improve the life expectancy at global level in 20th-21st Century. This book will provide the in-depth knowledge of vaccine history, and development of new strategies to design efficacious and safe vaccine molecule. This book will cover the development of system vaccinology and their applications revolutionize the vaccine discovery. This will provide a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials.

My purpose to write this book to educate the students and researchers with modern development in the field of vaccinology and empowering the researcher with new tools and methodology for developing potential and immunogenic vaccines.

This book will be helpful to solve the curiosity of science and medical background students related with vaccinology and will be helpful to devise a new vaccine molecule to control the spread of new and emerging pathogens.

Systems biology is a rapidly expanding research discipline aiming to integrate multifaceted datasets generated using state-of-the-art high- throughput technologies such as arrays and next-generation sequencing. Combined with sophisticated computational analysis we are able to interrogate host responses to infections and vaccination on a systems level, thus generating important new hypotheses and discovering unknown associations between immunological parameters.

Key features

  • Provides in-depth knowledge of vaccine history
  • Covers the development of system vaccinology and their applications revolutionize the vaccine discovery
  • Gives insights to the development of new strategies to design efficacious and safe vaccine molecule
  • Provides a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials
  • Highlights the importance of differential miRNA expression, microbiome after vaccination for human health
  • Serves the need of students and researcher for applying computational tools and quick designing of potential molecule which may be proposed for vaccine trial
  • Take the decisions to perform the kind of experiments for assessment of vaccine immunogenicity
  • Aims to understand disease pathogenesis and host responses to infection and vaccination
  • Offers a seamless continuum of scientific discovery and vaccine invention

Readership

students and researchers in immunology, microbiology, pharmacology
post graduate students, PhD, clinical and basic researchers in antigenic immune response and vaccine development,

Table of contents

Part I History and Introduction

1. Vaccine: History and its perspective

2. Evolution of human infectious diseases and vaccine

Part II Immunology of Vaccine Designing

3. Omics and databases of vaccine

4. Adjuvant requirement for vaccines

5. Vaccine Engineering and Structural vaccinolog

6. Vaccine and genome

7. Vaccine and transcriptome

8. miRNA and immunization

9. Vaccine and proteome

10. Vaccine and microbiome

Part III Delivery and Vaccine efficacy

11. rDNA technology and vaccines

12. Developing delivery system for vaccines

13. Infection, immunity and vaccine

14. Animal model and vaccines pre-clinical testing

15. Vaccine human clinical trial

Part IV Vaccine future and Ethics

16. Future of system vaccinology

17. Vaccine regulation and ethics

Product details

  • Edition: 1
  • Latest edition
  • Published: August 25, 2022
  • Language: English

About the editor

VP

Vijay Kumar Prajapati

Dr. Vijay Kumar Prajapati is an Associate Professor in the Department of Biochemistry at the University of Delhi South Campus, New Delhi, India. He specializes in cell-death research, parasitology, and therapeutic developments for infectious diseases. He has published extensively in international journals and contributed chapters to reputable publishers. He is a recipient of the INSA Medal for Young Scientist from the Indian National Science Academy and an Associate of the Indian Academy of Sciences, Bengaluru. His work has appeared in leading journals spanning infectious diseases and cellular physiology, reflecting a high scholarly impact and a broad research portfolio.

Affiliations and expertise
Department of Biochemistry, University of Delhi South Campus, India

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