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The Brainstem

  • 1st Edition, Volume 216 - March 20, 2026
  • Latest edition
  • Editors: Lea Tenenholz Grinberg, Amos D. Korczyn
  • Language: English

This volume on Brainstem consolidates research for a complete understanding of the anatomy and physiology of the Brainstem and how it affects assorted other systems in the body.… Read more

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Description

This volume on Brainstem consolidates research for a complete understanding of the anatomy and physiology of the Brainstem and how it affects assorted other systems in the body. The brainstem impacts breathing, the gastrointestinal system, the cardiac system, mood, pain, wakefulness, consciousness, and sleep. Pathologies can impact vision, motor control, hearing, balance, blood supply and is particularly involved in neurodegenerative diseases like Parkinson’s. The volume discusses how the brainstem operates in full health, pathologies associated with the brainstem and their impact, methods for monitoring brainstem function, and diagnosis and treatment of brainstem disorders. Monitoring and intervention is reliant on technologies to assess function. This volume will include CT, MRI, USG, angiography, BERA, and functional imaging.

Key features

  • Presents brainstem anatomy and physiology
  • Discusses brainstem impact on body systems
  • Reviews techniques for brainstem monitoring
  • Identifies brainstem pathologies and disorders
  • Includes best practices for diagnosis and interventions

Readership

Practicing Clinical neurologists, research academic neurologists, Advanced students in med schools or neurology depts

Table of contents

SECTION I Physiology and semiology

1. History of the brainstem—A developing concept throughout the history of medicine

2. Structural and functional anatomy of the brainstem

3. Autonomic blood pressure control

4. Brainstem in pain control

5. Brainstem control of sleep, wakefulness, alertness, and consciousness
SECTION II Pathology

6. Locked-in syndrome

7. The vestibular system: Unsteadiness, dizziness, and vertigo

8. Oculomotor disorders and nystagmus

9. Pupillary disorders

10. Neurodevelopmental brainstem syndromes

11. Intrinsic pontine tumors: Pathology of brainstem tumors and exploration of diffuse intrinsic pontine glioma

12. Autoimmune maladies of the brainstem

13. Dysarthria

14. The brainstem in neurodegenerative diseases

15. Brainstem vascular syndromes

16. Traumatic brainstem injury
SECTION III Monitoring and intervention

17. Computed tomography and magnetic resonance imaging of the brainstem

18. Ultrasound studies of brainstem

19. Anatomic imaging: Angiography

20. Brainstem evoked responses

21. Functional and molecular brainstem imaging

22. Brain death and the brainstem

Product details

  • Edition: 1
  • Latest edition
  • Volume: 216
  • Published: March 26, 2026
  • Language: English

About the editors

LG

Lea Tenenholz Grinberg

Dr. Lea Tenenholz Grinberg is a neuropathologist specializing in brain aging and associated disorders, most notably, Alzheimer’s and neurological basis of sleep disturbances in neurodegenerative diseases. Currently, she is a Full Professor and a John Douglas French Alzheimer’s Foundation Endowed Professor at the UCSF Memory and Aging Center, part of the Executive Board of the Global Brain Health Institute and member of the Medical Scientific Advisory Group for the Alzheimer Association. She is also a Professor of Pathology at the University of Sao Paulo.

In 2003, Dr. Grinberg was among the founders of a brain bank in São Paulo, focusing on brain aging. This brain bank which she had since developed into an extremely prolific and highly-regarded institution, helped Dr. Grinberg prove that, contrary to what has been accepted previously, the brainstem and not the cortex, harbors the first detectable neurodegeneration in Alzheimer’s disease. In 2009, she was the recipient of the UNESCO-L'Oréal Award "For Women in Science," and in 2010 she received the John Douglas French Alzheimer Foundation "Distinguished Research Scholar Award." Currently, Dr. Grinberg is the Co-Leader of the UCSF/Neurodegenerative Disease Brain Bank, where she conducts neuropathological diagnosis of neurodegenerative diseases. She also directs the Human Biology Validation Core for the NIH/U54 Tau Centers Without Walls, is a principal investigator from the Tau

Affiliations and expertise
Full Professor and a John Douglas French Alzheimer’s Foundation Endowed Professor, UCSF Memory and Aging Center, Brazil

AK

Amos D. Korczyn

Professor Korczyn graduated from the Hebrew University–Hadassah Medical School in Jerusalem in 1966 (MD), where he also received an MSc degree in pharmacology (cum laude) in 1966. He trained in neurology at Beilinson Hospital and at the National Hospital for Nervous Diseases, Queen Square, London. He was the Chairman of the Department of Neurology at the Tel-Aviv Medical Center from 1981 until 2002, and the incumbent of the Sieratzki Chair of Neurology at Tel-Aviv University, 1995-2010. Professor Korczyn has a particular interest in neurodegenerative diseases. He has authored or co-authored over 700 articles in peer-reviewed journals, edited several books and is Regional Editor of the Journal of Alzheimer’s Disease. He is or has been an Editorial Board member of 20 international journals, and organized several neurological conferences, mainly in the field of dementia, Parkinson’s disease and other degenerative brain disorders, as well as CONy – the International Congress on Controversies in Neurology, and has organized the Mental Dysfunction in Parkinson’s disease congresses since 1993. Professor Korczyn served on advisory boards in several drug discovery programs. Professor Korczyn is the Chairman of the Scientific Medical Board of the Israeli Alzheimer’s disease association (EMDA), member of the SAB of Alzheimer Disease International (ADI), and has been the chairman of the WFN Research Committee for Clinical Neuropharmacology. Professor Korczyn is an honorary member of the neurological societies of Israel, Serbia, Poland, Russia, and Romania.
Affiliations and expertise
Sieratzki Chair of Neurology, Israel

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