The Cytokines of the Immune System
The Role of Cytokines in Disease Related to Immune Response
- 2nd Edition - July 1, 2026
- Latest edition
- Editor: Zlatko Dembic
- Language: English
Cytokines of the Immune System: The Role of Cytokines in Disease Related to Immune Response, Second Edition is a comprehensive and essential resource for graduate and postgr… Read more
Description
Description
These insights are invaluable for inspiring new drug designs and therapeutic strategies. The book delivers a thorough overview of immunology, detailing the development and regulation of the immune system, with a special focus on cytokines. It presents an upgraded description of interleukins, immune-modulatory cytokines, and chemokines, exploring their structure, sources, functions, receptors, disease associations, and therapeutic potentials. This edition also introduces the latest information on innate lymphoid cells and their cytokines, as well as their adaptive immunity counterparts. A dedicated chapter on the cytokine storm provides critical insights into this phenomenon.
Key features
Key features
- Provides comprehensive updates on cytokine research, including novel figures that illustrate structure-function-signaling relationships
- Explores innate immunity cells, their interactions, and cytokine fingerprints
- Includes data on cytokine roles in T- and B-cell activations in the adaptive immune system
- Discusses cytokine networks and the cytokine storm in detail
- Covers therapeutic options for cytokines, aiding treatment decisions for cancer, infections, and autoimmune diseases
Readership
Readership
Table of contents
Table of contents
2. The Immune System: Definition and Development of Immunity
3. Activation of Cells of the Immune System
4. The Role and Regulation of the Immune Responses
5. Innate Immunity Cytokines with Pro- and Anti-inflammatory Activities
6. Innate Immunity Cytokines with Antiviral Properties: Interferons
7. Cytokines Shaping Adaptive T and B Cell Responses
8. Chemokines: Cytokines Controlling Cellular Migrations
9. Cytokine Networks and Cytokine Storm
10. Theories About the Function of the Immune System
Product details
Product details
- Edition: 2
- Latest edition
- Published: July 1, 2026
- Language: English
About the editor
About the editor
ZD
Zlatko Dembic
Dr. Zlatko Dembic, a distinguished scientist and medical doctor, has dedicated his career to exploring the intersections of medicine and biology, particularly in molecular and cellular immunology. Over the last two decades of the 20th century, he worked at prestigious institutions such as the Max-Planck-Institute for Biology in Germany, the Basel Institute for Immunology in Switzerland, and Hoffman-La Roche AG. His team was the first to identify genes underlying T-cell specificity and recognition, and they led the molecular cloning of key human cytokine receptors like the interferon-gamma receptor and the tumor necrosis factor receptor-2. In 1995, Dr. Dembic joined the Institute of Immunology at the University of Oslo, expanding his research to include T-cell development, cancer immunobiology, and immunogenetics. He proposed the "integrity" model of the immune system, emphasizing immunity's role in defense and symbiont selection and has over 100 scientific publications in many high impact factor scientific journals.