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The Gut Microbiome in Precision Medicine

From Research to Clinical Practice

  • 1st Edition - March 13, 2026
  • Latest edition
  • Editor: S Rehan Ahmad
  • Language: English

The Gut Microbiome in Precision Medicine: From Research to Clinical Practice explores the significant role of the gut microbiome in health and disease, particularly within gastro… Read more

Description

The Gut Microbiome in Precision Medicine: From Research to Clinical Practice explores the significant role of the gut microbiome in health and disease, particularly within gastrointestinal conditions such as inflammatory bowel disease, irritable bowel syndrome, and colorectal cancer. It covers how understanding and analyzing the gut microbiome can lead to personalized treatments, dietary plans, and precision medicine approaches in gastroenterology. Chapters explore multi-omics integration, examining complex techniques for gut microbiome profiling, including genomics, transcriptomics, proteomics, and metabolomics. Users will find updates on microbiome-based interventions, such as probiotics, prebiotics, and personalized nutrition that highlight practical applications in gastrointestinal disease management.

Real-world examples and case studies discuss strategies for overcoming barriers to implementing microbiome analysis. Additionally, it addresses the challenges and opportunities of implementing microbiome analysis in clinical practice, with a special emphasis on its implications for developing countries. Finally, the book covers emerging technologies in microbiome research and their applications in gastroenterology, emphasizing future directions and research priorities.

Key features

  • Helps readers gain a comprehensive understanding of the latest gut microbiome research and its impact on precision medicine, covering foundational concepts, advanced methodologies, and cutting-edge technologies
  • Provides practical insights for healthcare professionals on integrating personalized gut microbiome profiling into clinical practice to design targeted treatment plans and dietary interventions for improved patient outcomes
  • Allows researchers to explore new research directions and methodologies, including multi-omics approaches, microbiome engineering, and microbiome-driven drug discovery

Readership

Gastroenterologists and other healthcare professionals working in the field of precision medicine Researchers studying the role of the microbiome in health and disease

Table of contents

Section I: Introduction to the microbiome and precision medicine


1. Definition and importance of the human microbiome
Arushi Gupta, Muskan Syed, Alakto Choudhury, Priyanka Narad, Abhishek Sengupta

2. Precision medicine in gastroenterology: applications and microbiome alterations
Mairaj Ahmed Ansari, Sadqua Urooj, Draksha, Yanchen Tamang, Afreen Rehman

3. Foundations of the gut microbiome: understanding microbial ecology
Priyanshu Kalia, Michael Angelis, Anupama Rani, Danish Qavi

4. Decoding the gut microbiome: A comprehensive overview of its composition, key influencing factors, modulation approaches, and emerging characterization tools
Arti Gaur, Geetanjali Ganguli, Sree R Nair, Rhea Nawalkar, Archana Jethwa, Juili Mirgule

5. Epigenetic influences of the gut microbiome: a new frontier in medicine
Faiza Naseer, Hina Khan, Bushra Rehman, Palwasha Ahmad, Fatima Tariq, Memoona Rauf

Section II: Multi omics integration: unraveling the complexities of the gut microbiome


6. Unravelling the microbiome: the fundamental role of multi omics approaches in understanding microbial communities
Nabanita Mukherjee, Moumita Sil, Ankita Ghosh, Ishita Chatterjee, Arunava Goswami, Maria Poptsova

7. Advanced multi omics technologies in gut microbiome research
Saema Hanafi, Shamala Salvamani, Vaidehi Ulaganathan, Digsha Augundhooa, Mahla Chambari, Kirtana Devi, Nilofar Firoz, Baskaran Gunasekaran

8. Challenges in integration of multiomics in gut microbiome
Shrikant Verma, Sushma Verma, Mohammad Abbas, Farzana Mahdi

9. Comprehensive analysis of the gut microbiome: techniques, challenges, and innovative tools
Sukanta Bhadra, Prachetash Ghosh, Sk Erfanul Haque

10. Challenges and limitations of microbiome analysis
Shahana Barbhuiya, Antara Bhattacharjee

11. Precision profiling for tailored health solutions
Sanchita Srivastava, Riya Nag, Ale Eba, Arif Hussain, Syed Tasleem Raza

12. Advanced methods and technological advances in personalized microbiome research
Sindhuprava Rana, Vibhor Joshi, Pramod Kumar, Maneesh Kumar, Ganesh Chandra Sahoo

13. Standardization and quality control in microbiome analysis
Faiza Naseer, Sana Javed, Rashid Hussain, Quratul Ain, Fahama Syed, Maryam Sadia

14. Microbiome biomarkers and multiomics approaches in precision medicine
Furqan Choudhary, Adib Khan, Mairaj Ahmed Ansari, Ram Prasad, Humaira Farooqi

15. Definition and importance of microbiome biomarkers
Mairaj Ahmed Ansari, Draksha, Aymar Akilimali, Sadqua Urooj, Yanchen Tamang

16. Overview of microbiome biomarkers and their applications in gastroenterology
Farha Azmeen, Kunal Kishor, Pooja Jha, Puja Das

Section III: Microbiome based interventions: probiotics and prebiotics


17. Personalized gastroenterology: Inflammatory bowel disease
Saher Mahmood, Areeba Saeed, Shahid Nawaz, Maira Saleem

18. Role of the gut microbiome in the pathogenesis of inflammatory bowel disease
Sudipta Banerjee, Pieu Adhikary, Debjit De, Abul Kalam, Subhankar Chowdhury, Chittabrata Mal

19. Microbiome based biomarkers for inflammatory bowel disease diagnosis and prognosis
Muhammad Zaid Salar, Naila Ghafoor, Ayesha Ghafoor, Atif Amin Baig

20. Harnessing gut microbiome and multi omics integration for next generation therapeutic strategies
Jasmine R, Sowmiya Soundararajan, Navaraj Selvakumar Balasingh, Jenova Mercy J

21. Personalized gastroenterology: irritable bowel syndrome
Koushik Sen, Suravi Majumder, Md Shariful Islam, Sanjib Kumar Das, Nithar Ranjan Madhu

22. Personalized gastroenterology: Irritable bowel syndrome
Ritwik Acharya, Anupriya Kumari

23. Exploring the gut microbiome’s influence on irritable bowel syndrome: clinical insights and future directions
Ghulam Mustafa, Amara Tahir, Rao Zahid Abbas, Khadija Javed

24. Microbiome based biomarkers for irritable bowel syndrome diagnosis
Prashanth Kotthapalli, Ann Catherine Archer

25. Microbiome based interventions for irritable bowel syndrome management
Khushboo Chaudhary, Himaani Mehra, Neena Kumar Dhiman

26. Personalized gastroenterology: colorectal cancer
Adil Parvez, Faizullah Jafar, Md Zaid Hussain Siddique, Namrah Parveen, Priyanka Das, Kamal A. Qureshi

27. Role of the gut microbiome in the development of colorectal cancer
Anirudh P. Shanbhag

28. Microbiome based biomarkers for colorectal cancer screening and early detection
Meenakshi Bandyopadhyay, Abul Kalam

29. Microbiome based interventions for colorectal cancer prevention and treatment
Nurul Akmaryanti Abdullah, J.V. Jayasurya, M.P. Laavanyaa Shri, R. Margrate Thatcher, Basak Dalbayrak, Elif Damla Arısan, S. Ambika, Y. Manojkumar

30. Advances in probiotic–prebiotic science: mechanisms, clinical applications, and emerging microbial therapeutics
Khushi Modi, Sakshi Gohil, Tabassum Khan, Renitta Jobby, Pamela Jha

31. Mechanisms of action of probiotics and prebiotics
Neena Kumar Dhiman

32. Bacillus coagulans: basic and applied aspects
Moumita Sil, Sutirtha Banerjee, Nabanita Mukherjee, Ankita Ghosh, Arunava Goswami, Igor Polikarpov

33. Personalized nutrition and the microbiome
Digsha Augundhooa, Baskaran Gunasekaran, Mahla Chambari, Fenglong Fan, Sree V. Chintapalli, Vaidehi Ulaganathan

34. Role of diet in shaping the gut microbiome
Bilal Siddiqui, Sakshi Tiwari, Saman Fatima, Malik Zainul Abdin

35. Personalized nutrition plans based on gut microbiome analysis
Mark Rector Charles, Denys Charles

36. Precision nutrition in gastrointestinal disease management: mechanisms, preventive strategies, and therapeutic applications
Hiral Pandya, Khushi Modi, Sakshi Gohil, Tabassum Khan, Renitta Jobby, Pamela Jha

37. Implementing microbiome analysis in clinical practice
Shashank Nand Tiwari, Suman Kumar, Maneesh Kumar, Shyam Kishor Kumar, Pratima Gupta

38. Challenges and barriers to implementing microbiome analysis in clinical practice
Ganesh Chandra Sahoo, Roshan Kamal Topno, Maneesh Kumar, Bibekananda Bhoi, Sindhuprava Rana, Krishna Pandey

39. Implementing microbiome analysis in clinical practice: overcoming challenges
Maneesh Kumar, Suman Kumar, Ratnesh Kumar, Ravikant Singh, Bibekananda Bhoi, Gaurav Kumar, Pratima Gupta

40. Case studies of successful implementation of microbiome analysis in clinical practice
Sagnik Mondal, Gajendra Singh

41. Unique challenges faced by developing countries in implementing microbiome based interventions
Maneesh Kumar, Nisha Jha, Mithilesh Kumar Jha, Ratnesh Kumar, Vimal Singh Munda, Pratima Gupta

42. Personalized medicine in gastroenterology
Hubza Ruatt Khan, Kashaf Junaid, Noor Muhammad, Ayesha Tariq, Mr. Slahuddin, Humaira Yasmeen

43. Examples of successful microbiome based interventions in developing countries
Qurrat Ul Ain

44. Barriers to implementation in precision medicine
Puja Karmakar, Subhashree Priyadarsini

45. Bioethical challenges in the era of precision medicine
Hubza Ruatt Khan, Hafiza Masuma Faheem, Unzish Qamar, Iram Asim, Iqra Afzal, Humaira Yasmeen

46. Artificial intelligence in precision medicine: enhancing predictive analytics
Subhashree Priyadarsini, Puja Karmakar

47. CRISPR and genome editing: precision tools for personalized therapies
Poonam Ranga

Section IV: Future directions and research priorities in gut microbiome personalized medicine


48. Potential applications of microbiome research in other areas of gastroenterology
Nandita Mandal, Avijit Bej, Anwesha Das, Arijit Nandi

49. Collaboration and international efforts to advance the field of precision gastroenterology
Varsha Singh, Nilofar Firoz

Product details

  • Edition: 1
  • Latest edition
  • Published: March 18, 2026
  • Language: English

About the editor

SA

S Rehan Ahmad

Dr. S Rehan Ahmad is a multidisciplinary scientist whose research bridges microbiology, medicinal chemistry, neurobiology, and precision medicine. Earning his Ph.D. in Microbiology, his pioneering work explores the pharmacogenomics and microbiome-based modulation of neurodegenerative diseases, with a focus on plant-derived therapeutics and molecular docking-driven drug discovery. His research integrates molecular microbiology, analytical chemistry (HPLC–MS), bioinformatics, and nanobiotechnology to advance novel therapeutic strategies. He holds over 30 patents and has published more than 60 peer-reviewed articles in high-impact journals, including Nature, Elsevier, Wiley, Springer, Frontiers and MDPI. He has edited two books published by Elsevier: The Gut Microbiome in Precision Medicine: From Research to Clinical Practice which focuses on the gut microbiome’s role in health, and Precision Medicine in Neurodegenerative Diseases: From Research to Clinical Practice, covering personalized medicine for neurodegenerative disorders.

His editorial experience is extensive, serving as Academic Editor for PLOS ONE, Editorial Board Member for over 15 international journals, and Guest Editor for JoVE. Recognized for his academic leadership, he serves as Coordinator of the Indira Gandhi National Open University (IGNOU) Study Centre (28166), Centre Superintendent (28166), and Convenor of multiple institutional committees including the Research & Development Cell (RDC), Intellectual Property Rights Cell (IPR), and Institution’s Innovation Council (Ministry of Education, Government of India). His teaching experience spans over 12 years in microbiology, neurobiology, medicinal biochemistry, food chemistry, and bioinformatics, mentoring more than 40 postgraduates and three doctoral researchers.

Affiliations and expertise
Assistant Professor and Head, Department of Microbiology, West Bengal State University, India

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