The Human Hypothalamus
Neuroendocrine Disorders
- 1st Edition, Volume 181 - July 4, 2021
- Latest edition
- Editors: Dick F. Swaab, Ruud M. Buijs, Paul J. Lucassen, Ahmad Salehi, Felix Kreier
- Language: English
The Human Hypothalamus: Neuroendocrine Disorders, Volume 181 in the Handbook of Clinical Neurology series, provides comprehensive summaries of recent research on the brain and ner… Read more
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Description
Description
Key features
Key features
- Discusses the importance of the hypothalamus in human growth and development
- Reviews hypothalamic related tumors, as well as pituitary, autoimmune, vasopressin and hormone regulation disorders
- Includes metabolic and eating disorders
- Identifies mechanisms of disease action and etiology
- Provides best practice information for assessment and treatment
Readership
Readership
Table of contents
Table of contents
1. Introduction: The human hypothalamus and neuroendocrine disorders
SECTION 15 Structural disorders of the hypothalamo-pituitary region
2. Pituitary stalk interruption syndrome
3. Empty sella syndrome: Multiple endocrine disorders
4. Pituitary dysfunction after aneurysmal subarachnoidal hemorrhage
5. Septo-optic dysplasia
SECTION 16 Tumors of the hypothalamus
6. Hypothalamic hormone-producing tumors
7. Craniopharyngiomas primarily affecting the hypothalamus
SECTION 17 Neuroimmunological disorders
8. The stress-axis in multiple sclerosis: Clinical, cellular, and molecular aspects
9. Neuroendocrine manifestations of Langerhans cell histiocytosis
10. Neuroendocrine manifestations of Erdheim–Chester disease
11. Hypothalamitis and pituitary atrophy
12. Narcolepsy Type I as an autoimmune disorder
13. Neuromyelitis optica, aquaporin-4 antibodies, and neuroendocrine disorders
14. Antibodies against the pituitary and hypothalamus in boxers
15. Autoimmune diabetes insipidus
SECTION 18 Drinking disorders
16. Neuroimaging of central diabetes insipidus
17. Differential diagnosis of familial diabetes insipidus
18. The vasopressin–aquaporin-2 pathway syndromes
19. Adipsic diabetes insipidus
20. Animal models for diabetes insipidus
21. Nocturnal enuresis in children: The role of arginine–vasopressin
SECTION 19 Eating disorders
22. Monogenic human obesity syndromes
23. Hypothalamic microinflammation
24. Glucose and fat sensing in the human hypothalamus
25. Hypothalamus and neuroendocrine diseases: The use of human-induced pluripotent stem cells for disease modeling
26. Prader–Willi syndrome: Hormone therapies
27. Transcriptomics of the Prader–Willi syndrome hypothalamus
28. Disorders of hypothalamic function: Insights from Prader–Willi syndrome and the effects of craniopharyngioma
29. Animal models for Prader–Willi syndrome
30. Is there a hypothalamic basis for anorexia nervosa?
SECTION 20 Reproduction, olfaction and sexual behavior
31. Sexual differentiation of the human hypothalamus: Relationship to gender identity and sexual orientation
32. Klinefelter syndrome or testicular dysgenesis: Genetics, endocrinology, and neuropsychology
33. Neurobiology of puberty and its disorders
Product details
Product details
- Edition: 1
- Latest edition
- Volume: 181
- Published: September 14, 2021
- Language: English
About the editors
About the editors
DS
Dick F. Swaab
Dick Swaab (1944) earned his medical and doctoral degrees at the University of Amsterdam, where he became involved in brain research during his third year of medical school. He was Director of the Netherlands Institute for Brain Research from 1978 to 2005. Since 1979 he is Professor of Neurobiology at the Medical Faculty, University of Amsterdam.
In 1985, Dr. Swaab founded the Netherlands Brain Bank (NBB) to serve as a source of clinically and neuropathologically well-documented research tissue. Since its founding, the Brain Bank has provided samples from more than 4,000 autopsies to 500 research groups in 25 countries. He was director of the NBB until 2005.
He is Leader Research team Neuropsychiatric Disorders, Neth. Inst for Neuroscience, an institute of the Royal Netherlands Academy of Arts and Sciences (KNAW). Swaab is also appointed for 2011-2017 Chao Kuang Piu Chair of Zhejiang University, Hangzhou, P.R. China.
His major research interests focus on, sexual differentiation of the human brain in relation to gender identity and sexual orientation, aging of the brain, Alzheimer’s disease, the neurobiological basis of depression, suicide and eating disorders. He has published over 540 papers in SCI journals, authored more than 200 chapters in books, and edited more than 60 books. Swaab mentored 84 PhD students from which 16 are now full professor. He is “Companion in the Order of the Dutch Lion”, bestowed by her Royal Majesty Queen Beatrix of the Netherlands. In 2008 Swaab obtained the Academy medal for his role in national and international neuroscience.
Dick Swaab is author of the 2 volume monograph The Human Hypothalamus that appeared in the Handbook of Clinical Neurology series, Elsevier, Amsterdam (1000 pp) and the Dutch best seller We are our Brains (450.000 copies sold), that is translated in 14 languages. A children's version of the book (You are your brains) has also appeared in Dutch in 2013 and Russian (2014). Swaab's H-factor is 76.
RB
Ruud M. Buijs
PL
Paul J. Lucassen
AS
Ahmad Salehi
FK