The Inflammatory Process

List Of Contributors

Preface

Preface to First Edition

Contents of Other Volumes

Part I. Vascular Events in the Inflammatory Process

Chapter 1. Microvascular Aspects of Tissue Injury

I. General Aspects of Reaction

II. Specific Components

III. Summary

References

Chapter 2. Capillary Permeability

I. Structural Consideration

I. Introduction

II. Permeability of Capillaries

III. Capillary Structure

IV. Discussion of Various Mechanisms Proposed for the Control of Capillary Permeability

V. Summary and Conclusions

References

Chapter 3. Capillary Permeability

II. Physiological Considerations

I. Introduction

II. General Outline of Capillary Permeability

III. Modes of Transport through Capillary Walls

IV. Methods for Studying Diffusion Permeability of Capillaries

References

Chapter 4. Capillary Permeability

III. Connective Tissue

I. Historical Perspective

II. Morphology and Composition of Connective Tissue

III. Organization and Functions of Connective Tissue

IV. Physical Chemistry of Connective Tissue

V. Role of the Connective Tissue in Vascular Exchange

VI. Reaction of Connective Tissue of Certain Agents

VII. Connective Tissue Homeostasis

References

Chapter 5. Rheologic Factors in Inflammation

I. Introduction

II. Rheology of Normal Blood

III. Rheology of Inflammation

IV. Summary

References

Chapter 6. The Lymphatic System in Inflammation

I. Introduction

II. Structure

III. Permeable Paths through the Lymphatic Wall

IV. Functioning of the Lymphatic System

V. Effects of Inflammation on the Lymphatic System

VI. Effects of the Lymphatic System on Inflammation

VII. Therapeutic Measures

References

Chapter 7. The Sticking and Emigration of White Blood Cells in Inflammation

I. Introduction

II. History of the Problem

III. Fate of Emigrated Cells in the Extravascular Tissue

IV. The Influence of pH on the Emigration of White Cells

V. Relationship Between White Cell Sticking and Vascular Permeability

VI. Chemotaxis

VII. Electrochemical Factors

VIII. Summary

References

Chapter 8. Chemical Mediators

I. Introduction

II. Early Vascular Events in Inflammation

III. Endogenous Mediators of the Vascular Events

IV. Evidence for the Natural Role of Amines, Polypeptides, and Proteases in the Inflammatory Process

V. Inflammatory Response in Various Organs

VI. Conclusions

References

Chapter 9. Mediation of Increased Vascular Permeability in Inflammation

I. Introduction

II. Acute Inflammation

III. Trigger Mechanisms

IV. Leukocytes as Mediators

V. The Case against Mediators

VI. Delayed Hypersensitivity

VII. Unifying Hypothesis of Inflammation

VIII. Conclusions

Note Added in Proof

References

Part II. Hematological Considerations

Chapter 10. Hemostatic Mechanisms in Tissue Injury

I. Introduction

II. The Hemostatic Plug

III. Vascular and Tissue Factors in Hemostasis

IV. Hemostasis as a Whole

References

Chapter 11. Thrombosis

I. Thrombosis as an Initiator of Inflammation

II. Thrombosis as a Complication of Inflammation

III. Prevention of Thrombosis

References

Author Index

Subject Index