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Elsevier

The Leukemia-Lymphoma Cell Line Factsbook

  • 1st Edition - September 4, 2000
  • Latest edition
  • Author: Hans G. Drexler
  • Language: English

The Leukemia-Lymphoma Cell Line Factsbook represents an essential reference manual for all of the well-characterized leukemia-lymphoma cell lines currently available. It provid… Read more

Description

The Leukemia-Lymphoma Cell Line Factsbook represents an essential reference manual for all of the well-characterized leukemia-lymphoma cell lines currently available. It provides the most important facts, using the succinct and user-friendly format that has made the FactsBooks so popular with scientists and clinical researchers. Introductory chapters provide background and perspective for culturing malignant hematopoietic (blood forming) cell lines. These chapters are followed by over 400 comprehensive individual entries. Each cell line entry highlights essential clinical, immunological, genetic, and functional features and includes a comprehensive listing of references.

Key features

  • The full spectrum of malignant cell lines from all hematopoietic cell lineages
  • Sister cell lines and relevant subclones
  • Clinical data: patient, diagnosis, treatment status, and specimen source
  • Authentication of derivation and availability
  • Immunophenotype
  • Cytogenetic karyotype
  • Translocations and fusion genes
  • Receptor gene rearrangements and genetic alterations
  • Cell cultures aspects: establishment, medium, doubling time, growth
  • Cytochemical profile
  • Cytokine production and response to cytokines
  • Proto-oncogene and transcription factor expression/alteration
  • Functional features: differentiation induction, heterotransplantability
  • Special unique features
  • Key references

Readership

Research level scientists and clinicians in Immunology, Cell Biology, Genetics, Molecular Biology, Hematology, Oncology, Pharmacology, Toxicology, Biochemistry, and Virology

Review quotes

"This book is most timely and should be an essential component for all investigators involved in cell culture research."—John Bennett, University of Rochester Medical Center, 2002

Praise for the Series:
"...a growing series of excellent manuals."—MOLECULAR MEDICINE TODAY
"...essential works of reference..."—TRENDS IN BIOCHEMICAL SCIENCES

Product details

  • Edition: 1
  • Latest edition
  • Published: September 12, 2000
  • Language: English

About the author

HD

Hans G. Drexler

Affiliations and expertise
German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany

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