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Elsevier

The Microbiome and Cancer Treatment

Overcoming Resistance and Enhancing Efficacy

  • 1st Edition - May 3, 2026
  • Latest edition
  • Editors: Sadhna Aggarwal, Garima Malik, Arun Kumar Singh, Meenakshi Dhanawat
  • Language: English

The Microbiome and Cancer Treatment: Overcoming Resistance and Enhancing Efficacy delves into the intricate relationship between the microbiome and cancer treatment, highli… Read more

Description

The Microbiome and Cancer Treatment: Overcoming Resistance and Enhancing Efficacy delves into the intricate relationship between the microbiome and cancer treatment, highlighting the microbiome's critical role in drug resistance and therapeutic efficacy. The book's chapters are meticulously organized to provide a deep understanding of how the microbiome interacts with the immune system and influences cancer development and response to therapies. This book opens new avenues for investigation by providing a better understanding of the mechanisms of resistance and the role of microbiome alterations in chemoresistance.

Sections also address the complex "chicken-or-egg" relationship between microbiome alterations and chemoresistance. A diverse blend of chapters foster interdisciplinary collaboration across fields such as immunology, microbiology, oncology, and pharmacology, promoting holistic approaches to cancer treatment. Readers will benefit by gaining awareness and a better understanding of how the microbiome impacts health, particularly in the context of cancer, leading to more informed health choices.

Key features

  • Fosters a comprehensive understanding of the microbiome's role in cancer treatment, encouraging collaboration among researchers and healthcare professionals to develop holistic and innovative therapeutic strategies
  • Provides practical insights into microbiome-based strategies to overcome chemoresistance, such as the use of probiotics and prebiotics in cancer therapy
  • Explores how modulating the gut microbiome can enhance the efficacy of immunotherapies, offering actionable knowledge for the development of personalized and more effective cancer treatments

Readership

Researchers, healthcare professionals, and academics in the fields of oncology, microbiology, immunology, and pharmacology

Table of contents

1. Understanding the Microbiome: Microbiome and Immune System Interactions

2. The Microbiome: Its Impact on Cancer Development and Therapeutic Responses

3. Microbiome Dynamics in Cancer Treatment: Impact of Chemotherapy on the Microbiome

4. Microbiome as a Modulator of Immunotherapy: Synergistic Effects of the Microbiome in Immunotherapy

5. Microbiome-Based Strategies to Overcome Chemoresistance: Probiotics and Prebiotics in Cancer Therapy

6. Modulating gut microbiome in cancer immunotherapy: Harnessing microbes to enhance treatment efficacy

7. The Impact of the Microbiome on Resistance to Cancer Treatment with Chemotherapeutic Agents and Immunotherapy

8. Cancer pharmacomicrobiomics: targeting microbiota to optimize cancer therapy outcomes

9. Gut microbiome in modulating immune checkpoint inhibitors

10. Microbiome-based diagnostics and biomarkers: The search for mechanistic connections

11. Modulatory effects of gut microbiome in cancer immunotherapy: A novel paradigm for blockade of immune checkpoint inhibitors

12. Current challenges and Future Prospects for Microbiome Research in Cancer Treatment

Product details

  • Edition: 1
  • Latest edition
  • Published: September 1, 2026
  • Language: English

About the editors

SA

Sadhna Aggarwal

Dr. Aggarwal is currently a senior postdoctoral fellow at the MD Anderson Cancer Center, Texas, USA. She completed Ph.D. from AIIMS, New Delhi under supervision of Prof. S. N. Das. During PhD, wherein she successfully addressed various aspects of local immunopathology in oral squamous cell carcinoma (OSCC). She published dozens of articles and several book chapters. She is an editorial board member of several indexed reputed international journals.
Affiliations and expertise
MD Anderson Cancer Center, TX, USA

GM

Garima Malik

Garima Malik has completed her B. Pharmacy from Vaish Institute of Pharmaceutical Education and Research, Rohtak, and an M.Pharmacy from Chandigarh College of Pharmacy, Landran. She has more than 3 years of experience as an Assistant Professor in the Department of Pharmaceutics. Currently, she is working as an Assistant Professor at M.M College of Pharmacy, Maharishi Markandeshwar University, Mullana, Ambala, India. Ms Garima had about 1.5 years of experience as an officer in the Quality control department at Zenacts Pharma Manimajra, Chandigarh. Her M.Pharmacy project focused on the topic of “Preparation and evaluation of Fusidic acid loaded transferosomes amalgamated with gel for the management of burn wound infection”. She has published more than 10 publications, including 1 Patent, and 5 book chapters. Her area of interest is nanotechnology, hydrogels, biomaterials, and their application in drug delivery.
Affiliations and expertise
Chitkara college of pharmacy, Chitkara University Rajpura, Punjab, India

AS

Arun Kumar Singh

Arun Kumar Singh completed his M.Pharm in Pharmaceutics from Galgotias University, Greater Noida, India, and currently serves as an Assistant Professor in the Department of Pharmacy at Vivekanand Global University. His research interests span nano-formulation, blockchain, IoT, machine learning, artificial intelligence, big data analytics, cancer biology, and neuroscience. He has authored one book with IOP Publishing, contributed five book chapters with River Publishers, Denmark, and published 25 review articles, including two high-impact papers in Biochimica et Biophysica Acta (BBA) – Reviews on Cancer. Additionally, he has authored and edited 55 books with renowned publishers such as Elsevier, CRC Press, Wiley, and IOP Publishing. Recognized for his innovative mindset, leadership, and strong research acumen, Mr. Singh continues to advance interdisciplinary research in pharmaceutical sciences and healthcare technology.
Affiliations and expertise
Assistant Professor at Vivekanand Global University

MD

Meenakshi Dhanawat

Dr Meenakshi Dhanawat, is currently working as Associate Professor in Amity Institute of Pharmacy, Amity University Haryana. She has a background in Pharmaceutical Sciences with a specialization in Medicinal Chemistry. She has done Masters from NIPER, Mohali and the project was based on Glycosylamino acids. Her PhD is from IIT-BHU, Varanasi and she worked on CNS drug delivery targeting 5HT1A/2A receptor. Apart from that she has a vast experience in the extraction of herbal drugs. Area of interest are Synthetic Chemistry, Heterocyclic Chemistry, Nanotechnology, Drug Delivery, Prodrug and Co-Drug Drug Design Complexation, Polymer Chemistry, and their application in drug delivery.

She has 17 years of teaching and research experience. She has attended several national and international conferences in india and abroad the recipient of the travelship award in DDD section of AAPS-2010, National Biotechnology Conference, California, USA. She has been able to grab the international travel grant from DBT and DST for attending the International Conference at California, USA and Munich, Germany Respectively. She has also grabbed many other fellowships awards, which includes Rajiv Gandhi National Fellowship. She has Published more than 85 Research/Reviews along with Patent-06, Books 6, Book Chapter 22, Book Editor 02, Copyright 01.

Affiliations and expertise
Amity Institute of Pharmacy, Amity University, Haryana, India