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Elsevier

The Molecular and Clinical Pathology of Neurodegenerative Disease

  • 1st Edition - November 16, 2018
  • Latest edition
  • Authors: Patrick A. Lewis, Jennifer E. Spillane
  • Language: English

The Molecular and Clinical Pathology of Neurodegenerative Disease brings together in one volume our current understanding of the molecular basis of neurodegeneration in humans, t… Read more

Description

The Molecular and Clinical Pathology of Neurodegenerative Disease brings together in one volume our current understanding of the molecular basis of neurodegeneration in humans, targeted at neuroscientists and graduate students in neuroscience, and the biomedical and biological sciences. Bringing together up-to-date molecular biology data with clinical evidence, this book sheds a light on common molecular mechanisms that underlie many different neurodegenerative diseases and addresses the molecular pathologies in each. The combined research and clinical background of the authors provides a unique perspective in relating clinical experiences with the molecular understanding needed to examine these diseases and is a must-read for anyone who wants to learn more about neurodegeneration.

Key features

  • Provides an up-to-date summary of neurodegeneration at a molecular, cellular, and tissue level for the most common human disorders
  • Describes the clinical background and underlying molecular processes for Alzheimer’s disease, Parkinson’s, Prion, Motor Neuron, Huntington’s, and Multiple Sclerosis
  • Highlights the state-of-the-art treatment options for each disorder
  • Details examples of relevant cutting edge experimental systems, including genome editing and human pluripotent stem cell-derived neuronal models

Readership

Neuroscientists, graduate and undergraduate students in biological and biomedical sciences, post-doctoral fellows, researchers

Table of contents

1. An Introduction to Neurodegeneration2. Alzheimer’s Disease and Dementia3. Parkinson’s Disease4. The Prion Diseases5. The Motor Neuron Diseases and Amyotrophic Lateral Sclerosis6. Huntington’s Chorea7. Multiple Sclerosis

Product details

  • Edition: 1
  • Latest edition
  • Published: November 16, 2018
  • Language: English

About the authors

PL

Patrick A. Lewis

Dr. Lewis has been involved in research into neurodegeneration for over 15 years, investigating dementia, the prion diseases and, for the last 10 years, Parkinson’s disease. He has published over 50 peer-reviewed publications in the field of neurodegeneration, and organized a number of international conferences on Parkinson’s disease, with a particular focus on Leucine Rich Repeat Kinase 2 (LRRK2). With over a decade of teaching experience, he instructs on a wide range of neuroscience-related topics to both undergraduate and postgraduate students at the University of Reading and University College London.
Affiliations and expertise
University of Reading, and UCL Institute of Neurology, UK

JS

Jennifer E. Spillane

Dr. Jennifer Spillane is a neurology specialist registrar at the National Hospital for Neurology and Neurosurgery. She completed her PhD at the Institute of Neurology and has published peer-reviewed articles over a wide range of neurological topics. She has experience teaching both undergraduate and post graduate medical students.
Affiliations and expertise
National Hospital for Neurology and Neurosurgery, UK

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