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The Neuroscience of Deep Brain Stimulation

Research and Clinical Applications

  • 1st Edition - February 19, 2026
  • Latest edition
  • Editors: Yasin Temel, Abdelhamid Benazzouz, Ali Jahanshahi
  • Language: English

Neuroscience of Deep Brain Stimulation: Research and Clinical Applications begins by introducing readers to the foundational research and historical background of DBS, includ… Read more

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Description

Neuroscience of Deep Brain Stimulation: Research and Clinical Applications begins by introducing readers to the foundational research and historical background of DBS, including developmental experimental models for movement and psychiatric disorders. The second section reviews various clinical applications, including numerous and in-depth case studies. The final section identifies the mechanisms of action behind DBS, including cellular, metabolic, and neurochemical mechanisms. Internationally contributed, this book is an essential guide for anyone in the field of DBS.

Key features

  • Reviews the development of experimental models for movements and psychiatric disorders
  • Identifies brain pathologies that Deep Brain Stimulation has revolutionized
  • Summarizes major technological developments for Deep Brain Stimulation and how they have adapted to patients’ needs, including Epilepsy, Tourette’s Syndrome, and Depression

Readership

Neuroscientists, Neurologists, Neurophysiologists, Neurosurgeons, Psychiatrists, Psychologists, Physiotherapists, Engineers Industry (Medtronic, Abbott, Boston Scientific) DBS device companies! more than 20 SME’s

Table of contents

Part 1: Bench

1. The quest for a target and the beginning of the DBS-story

2. Early clinical application

3. Development of experimental models for movements disorders

4. Development of experimental models for psychiatric disorders

Part 2: Science behind the clinical application

5. Parkinson’s disease

6. Dystonia

7. Essential tremor

8. Epilepsy

9. OCD

10. Tourette Syndrome

11. Depression

12. Alzheimer’s disease

13. Other indications

Part 3: Mechanisms of action

14. Neurophysiological mechanisms

15. Cellular mechanisms

16. Metabolic mechanisms

17. Neurochemical mechanisms

18. Mechanisms investigated by imaging

Part 4. Future/perspectives

Product details

  • Edition: 1
  • Latest edition
  • Published: February 20, 2026
  • Language: English

About the editors

YT

Yasin Temel

Yasin Temel is a Professor of Neurosurgery, Medical Center in Maastricht University, Maastricht, The Netherlands.
Affiliations and expertise
Professor of Neurosurgery, Medical Center, Maastricht University, Maastricht, The Netherlands

AB

Abdelhamid Benazzouz

Research Director Abdelhamid Benazzouz works in the Neurodegenerative Dis Institute, Bordeaux University, France.
Affiliations and expertise
Research Director, Neurodegenerative Dis Institute, Bordeaux University, France

AJ

Ali Jahanshahi

Experienced academic researcher with a demonstrated history of working in the field of Neuromodulation and Neurodegenerative disorders. Head of functional neurosurgery section at the department of neurosurgery. Skilled in Fundamental Neuromodulation research and academic teaching, Neuroanatomy, Animal Models, Electrophysiology, Behavior, Stereology and Microscopy. Co-founder and coordinator of Neuromodulation Master Specialization at Maastricht University.
Affiliations and expertise
Associate Professor at the Department of Neurosurgery, Maastricht University Medical Center, Maastricht, the Netherlands (0.8fte; permanent) Associate Professor at the Netherlands Institute for Neuroscience (NIN) (0.2fte; permanent)

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