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Translational Neuroimmunology, Volume 7

Neuroinflammation

  • 1st Edition - June 16, 2023
  • Latest edition
  • Editors: Nima Rezaei, Niloufar Yazdanpanah
  • Language: English

Translational NeuroImmunology: Neuroinflammation updates on bench to bedside studies on neurological disorders that have immunological etiologies. The book covers neuroimmu… Read more

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Description

Translational NeuroImmunology: Neuroinflammation updates on bench to bedside studies on neurological disorders that have immunological etiologies. The book covers neuroimmunology and the principles of autoimmune and autoinflammatory neurological disorders, with multiple sclerosis as the main focus. The immunopathology, genetics and epigenetics, microbiome, diagnosis and treatment of multiple sclerosis will be explained in ten chapters. A chapter also examines distinct aspects of pericytes, with final discussions on the neurologic manifestations, diagnostic approaches and treatments of the various neuroimmune disorders and lessons learned from translational research on non-human primates and zebrafish.

All sections are presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research.

Key features

  • Gives an introduction on neuroimmunological diseases, from bench to bedside
  • Encourages the development of immunologic approaches to analyze the interaction and specific properties of nervous tissue elements during development and disease
  • Focuses on understanding and therapeutically manipulating immunological responses to injury, degeneration and autoimmunity in the central nervous system
  • Proves changes in relevant immune and inflammatory reactions at the cellular and molecular level during the development of nervous system diseases

Readership

Clinical immunologists, neurologists, Rheumatologist, Endocrinologists, Microbiologists, Oncologists, Rheumatologists, Clinicians, research scientists, and industry partners

Table of contents

1. Introduction on neuroimmunology

2. Neuroimmune interactions: from bench to bedside

3. Neuroimmunology: translational lessons from zebrafish

4. COVID-19-related neuroinflammation may reveal the triggers for healthy longevity

5. Role of neural-immune dysregulation in the periphery in the development of immune dysfunctions

6. Pericytes, a cell type contributing to immune tolerance and autoimmunity

7. Immunity and cognition

8. Neuroimmunology and sleep

9. Impact of systemic inflammation on neuroinflammation

10. Rare autoimmune and autoinflammatory neurologic disorders

11. Epstein-Barr virus and neuroinflammation

12. The potential role of dietary intervention for the treatment of neuroinflammation

13. Immune dysregulation and neurodegenerative diseases

14. Immunological Aspects of Glaucomatous Optic Neuropathy Etiology and Treatments

15. Imaging characteristics of neuroimmunological disorders

16. Contribution of neuroimaging studies to understanding of immunology and inflammation in epilepsy

17. Bedside to bench side translation with the targeting of the BAFF/APRIL axis in neurological autoimmune disorders

18. New insights on Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) as potential therapeutic target for immune mediated neurological disorders

19. Inflammasome Elements in Epilepsy and Seizures

20. Treatment Approaches to Neuroimmunological Diseases: Therapeutic Candidates Affecting Neuroinflammation

Product details

  • Edition: 1
  • Latest edition
  • Published: June 20, 2023
  • Language: English

About the editors

NR

Nima Rezaei

Professor Nima Rezaei gained his medical degree (MD) from Tehran University of Medical Sciences and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital. Professor Rezaei is now the Full Professor of Immunology and Vice Dean of Research, School of Medicine, Tehran University of Medical Sciences, and the co-founder and Head of the Research Center for Immunodeficiencies. He is also the founding President of the Universal Scientific Education and Research Network (USERN). Professor Rezaei has already been the Director of more than 55 research projects and has designed and participated in several international collaborative projects. Professor Rezaei is an editorial assistant or board member for more than 30 international journals. He has edited more than 35 international books, has presented more than 500 lectures/posters in congresses/meetings, and has published more than 1,000 scientific papers in the international journals.
Affiliations and expertise
Professor, Department of Immunology, School of Medicine; Head, Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences; Founding President, Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA),Universal Scientific Education and Research Network (USERN),Tehran, Iran

NY

Niloufar Yazdanpanah

Affiliations and expertise
Managing Director, Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA) Universal Scientific Education and Research Network (USERN); and School of Medicine, Tehran University of MEdical Sciences, Tehran, Iran

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