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Translational Neuroimmunology, Volume 8

Multiple Sclerosis

  • 1st Edition - June 16, 2023
  • Latest edition
  • Editors: Nima Rezaei, Niloufar Yazdanpanah
  • Language: English

Translational Neuroimmunology: Multiple Sclerosis provides an update on bench to bedside studies on Multiple Sclerosis as an autoimmune disease. Divided into twelve chapte… Read more

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Description

Translational Neuroimmunology: Multiple Sclerosis provides an update on bench to bedside studies on Multiple Sclerosis as an autoimmune disease. Divided into twelve chapters, the book begins with an in-depth introduction to the neuroimmunology and immunopathology of multiple sclerosis. Sections also provide content on genetics and epigenetics, the microbiome, diagnosis, and treatment of multiple sclerosis. Finally, various precision treatments are covered. All information is presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research.

Key features

  • Provides an introduction on multiple sclerosis as an autoimmune disease, from bench to bedside
  • Encourages the development of immunologic approaches to analyze the interaction and specific properties of nervous tissue elements during development and disease
  • Focuses on understanding and therapeutically manipulating immunological responses to injury, degeneration and autoimmunity in the central nervous system
  • Shows the changes in relevant immune and inflammatory reactions at the cellular and molecular level during the development of nervous system diseases

Readership

Clinical immunologists; neurologists, Rheumatologist; Endocrinologists; Microbiologists; Oncologists; Rheumatologists. Clinicians, research scientists, and industry partners.

Table of contents

1. Introduction on the Neuroimmunology of Multiple Sclerosis

2. Immunopathology of multiple sclerosis

3. Biomarkers of multiple sclerosis

4. Translational research into the pathogenesis of secondary progressive multiple sclerosis

5. Neuroimmunology of fatigue in multiple sclerosis

6. Microbiome and multiple sclerosis

7. Interaction with parasites and herpesviruses in people with multiple sclerosis - potential applications for prevention and treatment

8. Cytotoxic cells in multiple sclerosis: new targets for treatment

9. Targeting leukocytes in multiple sclerosis: therapeutic perspectives

10. Antibodies and antibody fragments developed for treatment of multiple sclerosis

11. Sphingosine-1-Phosphate, its Receptors, and their Role in Multiple Sclerosis, an Inflammatory and Autoimmune Disease of the Central Nervous Systems

12. Innate and adaptive immunomodulation by burton tyrosine kinase (BTK) inhibitors: review of emerging multiple sclerosis treatment

Product details

  • Edition: 1
  • Latest edition
  • Published: June 20, 2023
  • Language: English

About the editors

NR

Nima Rezaei

Professor Nima Rezaei gained his medical degree (MD) from Tehran University of Medical Sciences and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital. Professor Rezaei is now the Full Professor of Immunology and Vice Dean of Research, School of Medicine, Tehran University of Medical Sciences, and the co-founder and Head of the Research Center for Immunodeficiencies. He is also the founding President of the Universal Scientific Education and Research Network (USERN). Professor Rezaei has already been the Director of more than 55 research projects and has designed and participated in several international collaborative projects. Professor Rezaei is an editorial assistant or board member for more than 30 international journals. He has edited more than 35 international books, has presented more than 500 lectures/posters in congresses/meetings, and has published more than 1,000 scientific papers in the international journals.
Affiliations and expertise
Professor, Department of Immunology, School of Medicine; Head, Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences; Founding President, Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA),Universal Scientific Education and Research Network (USERN),Tehran, Iran

NY

Niloufar Yazdanpanah

Affiliations and expertise
Managing Director, Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA) Universal Scientific Education and Research Network (USERN); and School of Medicine, Tehran University of MEdical Sciences, Tehran, Iran

View book on ScienceDirect

Read Translational Neuroimmunology, Volume 8 on ScienceDirect