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Transplant Oncology

A Frontier in Multidisciplinary Cancer Care

  • 1st Edition - November 8, 2024
  • Latest edition
  • Editor: Maen A. Abdelrahim
  • Language: English

**Selected for 2025 Doody’s Core Titles® in Transplantation Surgery**Transplant Oncology: A Frontier in Multidisciplinary Cancer Care summarizes new and evolving scientific finding… Read more

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Description

**Selected for 2025 Doody’s Core Titles® in Transplantation Surgery**

Transplant Oncology: A Frontier in Multidisciplinary Cancer Care summarizes new and evolving scientific findings and discoveries in the field of cancer and transplants and gives guidance on future directions and related research. With a strong focus on transplant oncology, the book examines new and evolving topics, including the utilization of immunotherapy in special patient populations as well as the clinical updates on new concepts in the field such as using circulating tumor DNA (ctDNA) as a tool for minimal disease detection, surveillance, and treatment response evaluation as well as rejection assessment and detection in transplant patient for oncological indications.

Sections cover applications of transplant medicine and surgery in oncology to improve patient survival outcome and quality of life. The book gives insight into anticancer strategies, such as initiating studies in genomics and cancer immunogenomics based on new insights in liver cancer.
In addition, it describes how the adoption of surgical transplantation techniques in oncology has improved conventional resection and bridged the gap between tumor and transplant immunology. This is a must have reference for all those that want to be familiar and up-to-date with the dynamic changes in the field including practicing physicians, scientists, and trainees.

Key features

  • Illustrates the concept and history of transplant oncology as an evolving field for the management of hepatocellular carcinoma
  • Discusses the utility and safety of immunotherapy in the transplant setting
  • Summarizes the utilization of immune checkpoint inhibitor therapies in pre-and post-liver transplants for HCC patients and discusses the assessment of immune checkpoint inhibitor regulators that might determine liver transplant outcomes
  • Highlights new and evolving topics including the utilization of immunotherapy in special patient populations as well as the clinical updates on new concepts in the field, including treatment and rejection assessment

Readership

Practicing oncologists, hepatologists, immunologists, and surgeons both in the academic and private sectors as well as healthcare professionals who are members of cancer associations, cancer patient organizations, medical associations, Health decision-makers include the cabinet, health or deputy health ministers, parliamentarians, funding agencies, and community leaders

Table of contents

Section I: Transplant Oncology: An Evolving Field in Cancer Care

1. Transplant Oncology: concept, history, and evolution

2. Prehistory of Transplant Oncology Era

Section II: Transplantations for Oncological Indications

3. Hepatocellular Carcinoma

4. Cholangiocarcinoma and liver transplantation

5. Transplantation for Oncological Indications: Colorectal Cancer Liver Metastases

6. Liver transplantation for neuroendocrine neoplasms liver metastases

7. Hepatoblastoma

Section III: Transplant Oncology and Immunotherapy

8. Transplant Oncology and Immunotherapy: Immunotherapy and liver transplants

9. b. Immunotherapy and kidney transplant

10. Immunotherapy and Hematopoietic Stem Cell Transplantation

11. Immunotherapy in the Era of Transplant Oncology: Risks and Complications

12. Immunotherapy and immunosuppressants: Considerations in the clinical practice

Section IV: Transplant Oncology and Precision Medicine

13. Molecular profiling and Next-Generation Sequencing applications in transplant oncology

14. Circulating tumor DNA (ctDNA) as a new and evolving tool in solid organ transplantation

15. Cell-free DNA (cfDNA) biomarkers for solid organ transplant rejection

16. Artificial intelligence in transplant Oncology

Section V: Solid Organ Transplant and Cancers Considerations

17. De Novo malignancy Post Liver Transplantation: Recent Insights on Epidemiology and Surveillance Strategies

18. History of cancer and transplant clearance: Considerations prior to transplantation

Section VI: Surgical Aspects of Transplant Oncology

19. Robotic Surgery for Liver Cancer and Applications in Liver Transplantation

20. Resection versus Transplantation for Intrahepatic and Hilar Cholangiocarcinoma

21. Liver transplantations for secondary cancers: surgical considerations

22. New strategies for two-stage hepatectomy

23. Living Donor Liver Transplantation

24. Patient characteristics and evaluations prior to liver transplantation

25. Challenges of liver transplantation for transplant oncology indications

26. Future of transplant oncology of the liver

Review quotes

"This unique book addresses the intersection of two rapidly changing surgical fields—transplant and oncologic surgery. It considers all aspects of these fields in a series of highly detailed, carefully referenced chapters. Logically organized sections make liberal use of headings and subheadings as a guide to the desired material,... [and] carefully selected illustrations enhance the work. The purpose of the book is to delineate the ways in which these two specialties - oncology and transplant - affect each other. It serves as a detailed summary of current knowledge and suggests directions for future research.... This is a unique book; there are no comparable texts. As such, and due to the excellence of its coverage, it should find a place on the bookshelf of any specialists who work in these allied fields. It will also be useful to advanced trainees and researchers." Review by Joseph Lane Wilson, MD, FAAFP(University of Missouri - Kansas City School of Medicine), ©Doody's Review Service, 2025.

Product details

  • Edition: 1
  • Latest edition
  • Published: November 8, 2024
  • Language: English

About the editor

MA

Maen A. Abdelrahim

Dr. Abdelrahim is a gastrointestinal medical oncologist and transplant oncologist with unique experience in malignancies treated by liver transplantation. He is the section chief of GI medical oncology at Houston Methodist Neal Cancer Center. He is heavily involved in the transplant oncology field and have been one of the pioneers in the field. He has published more than 230 original research articles, review articles, and book chapters in prestigious journals and publishing groups. He is a member of the American Society of Clinical Oncology, Society for Immunotherapy of Cancer, Cholangiocarcinoma Foundation, European Society for Medical Oncology, and International Liver Transplant Society
Affiliations and expertise
Houston Methodist, Section, Chief Gastrointestinal Medical Oncology, Medical Director Cockrell Center for Advanced Therapeutics (CCAT), Houston, TX, USA

View book on ScienceDirect

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