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Zika Virus Impact, Diagnosis, Control, and Models

Volume 2: The Neuroscience of Zika Virus

  • 1st Edition - June 25, 2021
  • Latest edition
  • Editors: Colin R. Martin, Caroline Hollins-Martin, Victor R. Preedy, Rajkumar Rajendram
  • Language: English

Zika Virus Impact, Diagnosis, Control, and Models: Volume Two: The Neuroscience of Zika examines diagnosis, vaccines, and potential therapy methods for Zika virus syndrome.… Read more

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Description

Zika Virus Impact, Diagnosis, Control, and Models: Volume Two: The Neuroscience of Zika examines diagnosis, vaccines, and potential therapy methods for Zika virus syndrome. The book also details the neuroscience of Guillain-Barré syndrome, its effects and neuromuscular rehabilitation. It is designed to help readers better understand detection, therapies for Zika virus, preventative vaccines, diagnosis and associated microcephaly. Chapters on models enable further research and understanding. This book has applicability for neuroscientists, neurologists, virologists and anyone working to better understand the evolution and pathogenesis of Zika virus-related conditions.

Key features

  • Provides a broad range of topics related to the neuroscience of Zika, including its diagnosis, vaccines and therapy
  • Contains chapter abstracts, key facts, a dictionary of terms and summary points to aid in understanding
  • Discusses novel and non-pharmacological therapies, Guillain-Barré Syndrome and vaccine development
  • Features chapters on rat, mouse, and guinea pig models of Zika and case reports of Zika co-infection with chikungunya, dengue-2 and Guillain-Barré
  • Includes coverage of microcephaly and developmental delays and examines Zika outbreaks in Brazil, Honduras, Uganda, Jamaica and Mozambique

Readership

Designed for research and teaching purposes, it is suitable for neuroscientists, neurologists, virologists, health scientists, public health workers, doctors, pharmacologists and research scientists. It is valuable as a personal reference book and also for academic libraries that covers the domains of neurology and health sciences. It is also suitable for undergraduates, postgraduate, lecturers and academic professors.

Table of contents

Section A: Zika virus: Setting the scene

1. How Zika virus emerged and spread worldwideJoselio Maria Galvao de Araujo, Manuela Sales Lima Nascimento, Paulo Marcos da Matta Guedes, and Jose Verissimo Fernandes

2. Clinical neurological spectrum of adult and congenital ZIKV infection: An overview of virology, pathogenesis, and managementWalter Sze Tung Lam, Tay Wei Xuan, Paul Ananth Tambyah, and Derek Tuck Loong Soon

3. Classification of Zika virus sequences with respect to their species and subspeciesJoilson Xavier, Stephane Tosta, Talita Adelino, Vagner Fonseca, Marta Giovanetti, and Luiz Carlos Junior Alcantara

4. Health knowledge about Zika virus: Brazil aspectsAna Luiza Vilela Borges and Raquel Zanatta Coutinho

5. Zika virus infection and replication organelle biogenesisMasashi Arakawa and Eiji Morita

Section B: Microcephaly and congenital syndromes

6. Microcephaly: Zika and other congenital infectionsLawrence Frenkel and Fernando Gomez

7. Zika and impact on the nervous system in childrenAline Almeida Bentes and Erna Geessien Kroon

8. Use of induced pluripotent stem cells and cerebral organoids to profile Zika virus infection: Features and findingsFernanda Majolo, Daniel Rodrigo Marinowic, Pamella Nunes Azevedo, Guilherme Liberato da Silva, Denise Cantarelli Machado, and Jaderson Costa DaCosta

9. Zika, miRNAs, and microcephaly genesOmar Bagasra and Ewen McLean

10. Adherens junctions and cell polarity: What they are and how they relate to congenital Zika virus syndromeFelipe A. Bustamante-Barrientos, Roberto Henzi, and Luis Federico Batiz

Section C: Guillain-Barre syndrome

11. Severe Guillain-Barre syndromeSelman Kesici and Benan Bayrakci

12. Oxidative stress in Guillain-Barre syndrome and linkage with neurologySerdar Baraklı, Sadiye Gumusyayla, Gonul Vural, and Orhan Deniz

13. Neuromuscular effects and rehabilitation in Guillain-Barre syndromeThomas Harbo and Henning Andersen

14. Postinfectious demyelinating diseases: Guillain-Barre syndrome and beyondT. Foiadelli, C. Trabatti, G.L. Marseglia, and S. Savasta

15. Linking in placental alterations, Zika virus, and Guillain-Barre syndromeKissila Rabelo, Natalia Gedeao Salomao, and Marciano Viana Paes

Section D: Case studies and short reports

16. Case study: Neuroimaging of adults and Zika virusDiogo Goulart Correa and Luiz Celso Hygino da Cruz

17. Case study: Magnetic resonance imaging and babies with Zika virus infectionDiogo Goulart Correa, Heron Werner, and Luiz Celso Hygino da Cruz

18. A case study of Guillain-Barre syndrome associated with Zika virus infectionJose Luis Soto-Hernandez, Karina Carrillo Loza, and Steven Vargas Canas

19. Clinical manifestations and outcomes of Guillain-Barre syndrome complicating Zika virus infectionAyman Alboudi and Andrew Jameson

20. Auditory brainstem in Zika virus: Insights about brain development in microcephalyDimitri Marques Abramov, Tania Regina Saad Salles, Cecilia Hedin-Pereira, Maria Elizabeth Lopes Moreira, and Vladimir V. Lazarev

Section E: Methods, biomarkers, and diagnosis

21. Magnetic resonance imaging use in detecting neurological abnormalities in Zika virus infectionDiogo Goulart Correa, Heron Werner, Osvaldo J.M. Nascimento, and Luiz Celso Hygino da Cruz Junior

22. Magnetic modulation biosensing: How it works and how it can be used to detect the Zika virusShira Roth and Amos Danielli

23. RNA extraction techniques of different body fluids for Zika virus: Blood, genitourinary specimens, saliva, and other relevant fluidsShannon E. Ronca, Bonnie E. Gulas-Wroblewski, Rebecca B. Kairis, and Kristy O. Murray

24. Saliva and urine analysis of Zika virus using loop-mediated isothermal amplification (LAMP)Talita Castro

25. Graphene-based biosensors for the detection of Zika virusAmeya Chaudhari and Prajakta Dandekar

26. The ZIKV Detect IgM Capture ELISAAlison Jane Basile and Holly R. Hughes

27. Quantum dot-based fluoroassays for ZikaJessika F.F. Ribeiro, Maria I.A. Pereira, Paulo E. Cabral Filho, Giovannia A.L. Pereira, Beate S. Santos, Goreti Pereira, and Adriana Fontes

28. Serological detection of specific IgA antibodies against Zika virus nonstructural protein 1 contributes to diagnosis of acute Zika virus infectionsKatja Steinhagen, Viola Borchardt-Loholter, Konstanze Stiba, Julia Maria Klemens, Erik Lattwein, Sandra Saschenbrecker, and Wolfgang Schlumberger

29. Serological algorithms: How they can be used for differentiating ZIKV from DENV infectionDay-Yu Chao and Gwong-Jen J. Chang

Section F: Control, vaccines, and treatments

30. Aedes aegypti and the use of natural molecules for its control: Implications in the decrease of Zika diseaseStelia Mendez-Sanchez, Duverney Chaverra-Rodriguez, and Jonny Duque

31. Strategies of Zika virus control with larvicides and their toxic potential: A focus on pyriproxyfenPatricia e Silva Alves, Maria das Dores Alves de Oliveira, Teresinha De Jesus Aguiar Dos Santos Andrade, Nerilson Marques Lima, and Joaquim Soares da Costa Junior

32. Larvicides: Plant oils and Zika controlTaruna Kaura, Naveed Pervaiz, and Abhishek Mewara

33. Pyridobenzothiazolones as anti-flavivirus agents: Impact on Zika virusMaria Sole Burali and Giuseppe Manfroni

34. The development of human monoclonal antibodies against Zika virusCui Li and Zhiheng Xu

35. The Zika virus NS1 protein as a vaccine targetMark J. Bailey and Gene S. Tan

36. Zika vaccines must prevent sexual transmissionOmar Bagasra and Ewen McLean

37. Nucleoside analogue inhibitors for Zika virus infectionJean A. Bernatchez, Michael Coste, Byron W. Purse, and Jair L. Siqueira-Neto

38. Medicinal plants as promising source of natural antiviral substances against Zika virusJuliano G. Haddad, Gilles Gadea, Philippe Despres, and Chaker El Kalamouni

39. Protein kinase C as a target in the control of viruses and implication for Zika virusA.B. Blazquez and J.C. Saiz

40. Nanotechnology applied in the control and diagnosis of Zika virus and its vectorsGabriel Augusto Pires de Souza, Livia Sacchetto, Betania Paiva Drumond, Jonatas Santos Abrahao, Tulio Cesar Rodrigues Leite, Breno de Mello Silva, Anna Carolina Toledo da Cunha Pereira, Gustavo Portela Ferreira, Luiz Cosme Cotta Malaquias, and Luiz Felipe Leomil Coelho

Section G: Models and modeling

41. Neonatal microcephaly and humanized mouse models for Zika viral pathogenesis and immunityKimberly Schmitt, Tawfik Aboellail, and Ramesh Akkina

42. Use of liver cells to discover novel peptides for anti-Zika strategiesAhmad Suhail Khazali and Rohana Yusof

43. In vivo mouse models to investigate the microcephaly associated with Zika virusRaissa R. Christoff and Patricia P. Garcez

44. Zika virus infection with primates: Fetal outcomesSunam Gurung, Rachel Jordan, James Papin, and Dean Myers

Product details

  • Edition: 1
  • Latest edition
  • Published: July 4, 2021
  • Language: English

About the editors

CM

Colin R. Martin

Colin R. Martin RN, BSc, MSc, PhD, MBA, YCAP, FHEA, C.Psychol, AFBPsS, C.Sci is Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director of the Institute of Health and Wellbeing at the University of Suffolk, UK. He is a Chartered Health Psychologist and a Chartered Scientist. He also trained in analytical biochemistry, this aspect reflecting the psychobiological focus of much of his research within mental health. He has published or has in press well over 300 research papers and book chapters. He is a keen book author and editor having written and/or edited more than 50 books. These outputs include the prophetic insight into the treatment of neurological disease, Handbook of Behavior, Food and Nutrition (2011), Nanomedicine and the Nervous System (2012), Oxidative Stress and Dietary Antioxidants in Neurological Disease (2020), Zika Virus Impact, Diagnosis, Control and Models (2021), Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior and Diet (2021), Diagnosis and Treatment of Spinal Cord Injury (2022), The Neurobiology, Physiology, and Psychology of Pain (2022) and The Handbook of Lifespan Cognitive Behavioral Therapy: Childhood, Adolescence, Pregnancy, Adulthood, and Aging (2023). Professor Martin is particularly interested in all aspects of the relationship between underlying physiological substrates and behavior, particularly in how these relationships manifest in both acute and chronic psychiatric disorder. He has published original research germane to significant mental health disorders including the areas of schizophrenia, anxiety, depression, self-esteem, alcohol and drug dependency, high secure forensic mental health and personality disorder. He has a keen interest in the impact of postviral illness and is actively involved in clinical research post-Covid pandemic and in particular, the impact of Long Covid on psychological, neurological, physiological and social functioning. He is involved in collaborative International research with many European and Non-European countries.
Affiliations and expertise
Visiting Professor of Perinatal Wellbeing, Institute for Health and Wellbeing, University of Suffolk, Ipswich, UK

CH

Caroline Hollins-Martin

Dr. Hollins-Martin is a Professor of Maternal Health and has a background that has encompassed a career in women’s reproductive health that spans 30 years; the first 11 of these were spent as a clinical midwife in Ayrshire (Scotland) and 19 teaching and researching women’s reproductive health within universities. Caroline is an NMC Registered Midwife and Lecturer/Practice Educator. She is also a graduate and post graduate in psychology and a Member of the British Psychological Society (MBPsS).
Affiliations and expertise
Edinburgh Napier University, School of Nursing, Midwifery and Social Work, Edinburgh, UK

VP

Victor R. Preedy

Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.
Affiliations and expertise
Professor, Department of Clinical Biochemistry, King’s College Hospital, London, UK; Emeritus Professor, Faculty of Life Sciences and Medicine, King’s College London, UK; Visiting Professor, University of Hull, UK

RR

Rajkumar Rajendram

Dr Rajkumar Rajendram is a clinician scientist with a focus on internal medicine, anaesthesia, intensive care and peri-operative medicine. He graduated with distinctions from Guy’s, King’s and St. Thomas Medical School, King’s College London in 2001. As an undergraduate he was awarded several prizes, merits and distinctions in pre-clinical and clinical subjects.

Dr Rajendram began his post-graduate medical training in general medicine and intensive care in Oxford. He attained membership of the Royal College of Physicians (MRCP) in 2004 and completed specialist training in acute and general medicine in Oxford in 2010. Dr Rajendram subsequently practiced as a Consultant in Acute General Medicine at the John Radcliffe Hospital, Oxford.

Dr Rajendram also trained in anaesthesia and intensive care in London and was awarded a fellowship of the Royal College of Anaesthetists (FRCA) in 2009. He completed advanced training in regional anaesthesia and intensive care. He was awarded a fellowship of the Faculty of Intensive Care Medicine (FFICM) in 2013 and obtained the European diploma of intensive care medicine (EDIC) in 2014. He then moved to the Royal Free London Hospitals as a Consultant in Intensive Care, Anaesthesia and Peri-operative Medicine. He has been a fellow of the Royal College of Physicians of Edinburgh (FRCP Edin) and the Royal College of Physicians of London (FRCP Lond) since 2017 and 2019 respectively. He is currently a Consultant in Internal Medicine at King Abdulaziz Medical City, National Guard Heath Affairs, Riyadh, Saudi Arabia.

Dr Rajendram’s focus on improving outcomes from Coronavirus Disease 2019 (COVID-19) has involved research on point of care ultrasound and phenotypes of COVID-19. Dr Rajendram also recognises that nutritional support is a fundamental aspect of medical care. This is particularly important for patients with COVID-19. As a clinician scientist he has therefore devoted significant time and effort into nutritional science research and education. He is an affiliated member of the Nutritional Sciences Research Division of King’s College London and has published over 400 textbook chapters, review articles, peer-reviewed papers and abstracts.

Affiliations and expertise
Consultant, Medical Protocol Department, King Abdulaziz Medical City, Ministry of National Guard Heath Affairs, Riyadh, Saudi Arabia

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