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Elsevier

Academic Press

  • Plant Peptides

    Enzymatic Production and Health-Promoting Effects
    • 1st Edition
    • Tolulope Joshua Ashaolu + 2 more
    • English
    Plant Peptides: Enzymatic Production and Health-Promoting Effects provides up-to-date insights on the enzymatic production, bioactivity, and applications of plant-derived peptides. This comprehensive volume explores the role of plant-based proteins (PBPs) as sustainable alternatives to traditional animal proteins, highlighting their environmental and climatic benefits. The book examines the enzymology of proteolytic enzymes used to generate bioactive peptides from PBPs, detailing their bioaccessibility, stability, and bioavailability. It offers an in-depth analysis of the multifarious biological activities of these peptides, including their antioxidant, antimicrobial, and metal-binding properties. The book also addresses the technological and biological properties, limitations, and challenges of plant-based bioactive peptides for industrial uses. With a strong focus on practical implementation, the book discusses emerging strategies and advanced technologies for producing and analyzing bioactive peptides, such as in silico analysis, fermentation, and peptidomics. It provides insights into future research directions and potential applications, emphasizing the health-promoting effects of plant-based peptides in combating obesity, diabetes, hypertension, cancer, and neurodegenerative diseases. This book is an essential resource for food science researchers, nutritionists, and students of food science and nutrition. It also serves as a valuable reference for teachers, scientists, food supplement producers, food businesses, and biosciences and medical students interested in the latest advancements in plant-based proteins and bioactive peptides.

  • The Renaissance in GPCR Research and Drug Discovery

    Receptor Function, Receptor Structure, New Techniques, and Characterization of Drug Activity
    • 1st Edition
    • Terry P. Kenakin
    • English
    The Renaissance in GPCR Research and Drug Discovery: Receptor Function, Receptor Structure, New Techniques, Characterization of Drug Activity, Drug Discovery is a comprehensive reference for pharmacology researchers. It focuses on utilizing novel aspects of GPCR function for therapeutic advantage and applying new chemical types to modify GPCR behavior. Recent advancements have revitalized GPCR discovery, opening unexplored avenues for new drug development. The book's content is meticulously divided into five distinct parts, covering evolutionary perspectives, novel functions, investigative technologies, therapeutic modalities, and a broad range of GPCR ligands.Beyond these key topics, the book delves into the evolution of GPCRs as drug targets, the mechanisms behind their novel functions, and the latest technologies driving research and discovery. It also highlights new and recently approved therapeutic modalities and provides a broad coverage of GPCR ligands. Edited and authored by leading researchers, this book serves as an essential reference for drug discovery researchers and medicinal chemists, as well as AI researchers exploring this drug discovery space.

  • Social Determinants of Health in Surgery

    Research Methods and Clinical Review
    • 1st Edition
    • Steven A. Toms + 4 more
    • English
    Social Determinants of Health in Surgery: Research Methods and Clinical Review is a groundbreaking resource dedicated to examining the role of social determinants within surgical care. This book is designed for surgical trainees, healthcare providers, researchers, and policy administrators, offering a thorough exploration of how social factors impact surgical outcomes and practice. Featuring a detailed analysis of eleven key domains, it addresses the challenges and opportunities of integrating social determinants into surgical research and practice. The text provides essential guidance for those seeking to understand and improve patient outcomes through a broader, community-driven lens.In addition to its comprehensive coverage, the book delves into specialized topics such as big data analytics, ethical considerations, global health perspectives, pediatric surgical care, and clinical applications for research. It presents methodological guidance, including valuable tips and common pitfalls useful for readers at any stage of their surgical careers. The book also offers an in-depth review of social determinants research across ten major surgical specialties, highlighting significant trends, key studies, and current gaps in knowledge. Case studies and reflective interviews from experienced clinicians further enrich the reader’s understanding.

  • Operative Strategies in Pelvic Exenteration Surgery

    • 1st Edition
    • Michael E Kelly + 1 more
    • English
    Operative Strategies in Pelvic Exenteration Surgery is a reference for the surgical management of Pelvic Exenteration Surgery. It covers all aspects of surgery from the colorectal, urological, gynecological, and orthopedic point of view. Coverage consolidates the research of world-leaders and includes the history of exenterative study, outlining the current state and indicating future developments. The book also discusses the current surgical operative strategies for the management of locally advanced and recurrent pelvic neoplasms with illustrations, intra-op photos, and supplementary video material.Created from the experiences of an international collaboration of surgeons, this reference is the perfect reference for surgical oncologists, colorectal, gynecology, urology, and vascular surgeons as well as any group involved in complex pelvic surgery including complex open, laparoscopic, and robotic surgery.

  • Antimicrobial Resistance, Sepsis, and the Invisible Threats to Women’s Health

    • 1st Edition
    • Uzma Syed + 1 more
    • English
    Antimicrobial Resistance, Sepsis, and the Invisible Threats to Women’s Health focuses on the burden of antimicrobial resistance (AMR) and sepsis on women's health, providing the latest information to educate both global researchers and healthcare professionals. The book begins by introducing the fundamental concepts of antimicrobial resistance and sepsis, setting the stage for a deeper exploration of their impact on women's health. It examines the epidemiology of sepsis and antimicrobial resistance in women, highlighting key risk factors, research gaps, reproductive health, antimicrobial resistance, and sepsis in detail, and further emphasizing their disproportionate impact on women's health.Additional coverage includes strategies for recruiting women in clinical trials and research studies, exploring the One Health approach integrating women's health into the broader context of AMR and sepsis and the role of artificial intelligence and technology in combating AMR and sepsis. The book concludes with case studies of female patients and their families affected by AMR and sepsis.

  • Emergent Nanotherapeutics in Diabetic Complications

    • 1st Edition
    • Awanish Kumar + 1 more
    • English
    Emergent Nanotherapeutics in Diabetic Complications explores how cutting-edge nanotechnology is transforming the treatment of diabetes-related disorders beyond glycemic control. This comprehensive volume examines targeted, multifunctional nanoplatforms designed to address the wide range of comorbidities linked to diabetes, including vascular complications, metabolic dysfunctions, and impaired wound healing. Structured in five parts, the book spans from current nanoformulation strategies to emerging innovations such as CRISPR-Cas9 delivery, AI-guided nanoparticles, and 3D/4D printed nanostructures. Bridging the gap between preclinical research and clinical application, it offers valuable guidance on stimuli-responsive systems, biocompatible materials, and regulatory pathways. Emergent Nanotherapeutics in Diabetic Complications is essential for medical professionals, biomedical engineers, and pharmaceutical scientists seeking scalable, next-generation solutions for managing diabetic complications through nanomedicine.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 135
    • English
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Thermal System Design and Simulation

    • 2nd Edition
    • P.L. Dhar + 1 more
    • English
    Thermal System Design and Simulation covers the fundamental analyses of thermal energy systems that enable users to effectively formulate their own simulation and optimal design procedures. This reference provides step-by-step guidance on how to mathematically formulate objective functions and design constraints and develop strategies to solve them to obtain optimal solutions with minimal computational effort. The book uniquely illustrates the methodology of combining information flow diagrams to simplify system simulation procedures needed in optimal design. Expanded and updated for currency, Thermal System Design and Simulation includes case studies and a comprehensive presentation on the dynamics of thermal systems and control systems needed to ensure safe operation at varying loads. Designed to give readers the hands-on skills needed to develop their own customized software for simulating and designing thermal systems, this book is useful for anyone interested in obtaining advanced knowledge of thermal system analysis and design.

  • Sustainable Supply Chain Management

    Computational Approaches and Modelling
    • 1st Edition
    • Syed Mithun Ali + 3 more
    • English
    Sustainable Supply Chain Management: Computational Approaches and Modelling provides a comprehensive understanding of how computational approaches can be leveraged to address the challenges associated with sustainable supply chain management. It offers insights into emerging and advanced modelling techniques to optimize supply chain operations while considering environmental, social, and economic factors. This book will be a valuable resource for researchers, practitioners, and policymakers interested in understanding and implementing sustainable supply chain management practices through computational approaches and modelling. This book helps researchers understand the opportunities, challenges, and solutions by developing innovative computational tools and techniques to integrate sustainability considerations into supply chain decision-making processes.

  • Wellbeing and Ethics of Animals in Shelters

    • 1st Edition
    • Mandy Paterson + 1 more
    • English
    Wellbeing and Ethics of Animals in Shelters provides an up-to-date, all-in-one resource for animal care and shelter professionals seeking the latest guidance on improving sheltered animals’ quality of life. Central chapters review health and behavioral assessments for shelter animals, offer guidance for the care of shelter cats and dogs, and discuss key steps to the successful adoption of sheltered animals. Latter chapters explore the human component of shelter animal care. The book is an accessible and important resource for animal care and shelter professionals, animal welfare researchers, and students of animal behavior, biology, and veterinary sciences.Thousands of unwanted dogs, cats, and other animals are brought under the care of shelters around the world each year. The transition can be a frightening and stressful experience with physiological and behavioral implications for the animals. Written by renowned animal welfare experts, this book not only covers guidance on improving the lives of sheltered animals, but also explores how animals come to be under the care of shelters and the ethical considerations of sheltering animals.

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