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Elsevier

Academic Press

  • Immuno-oncology and Immunotherapy Part D

    • 1st Edition
    • Volume 196
    • English
    Immuno-oncology and immunotherapy, Part D, Volume 196 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Investigating the endothelial-immune axis in cancer, Establishing Tyro3, Axl, and Mertk Chinese Hamster Ovary (CHO) Reporter Cell Lines for Cancer Immunology and Therapeutic Applications, Amino acid analog-based labelling of the immunomodulatory cancer secretome, Human and mouse iNKT cell expansion and engineering with viral vectors, Next-generation deconvolution of the tumor microenvironment with omnideconv, and much more.Additional sections cover Comprehensive prediction of tumor neoantigens with NextNEOpi, Ex vivo profiling of organotypic tumor spheroids in 3D microfluidic culture, A flow cytometry-based assay for evaluation of T cell activation and degranulation in coculture systems, An adenosine production assay suitable for 2D and 3D cancer cell culture, Determination of lactate in the tumor interstitial fluid, Combined in vitro differentiation and cell sorting-based isolation of highly pure mouse bone marrow-derived basophils, Organ-on-Chip immunostaining method for three-dimensional identification and study of immune cells responding to drug-treated tumor cells, and much more.

  • New Developments in Redox Biology

    Fundamental Roles in Health and Disease
    • 1st Edition
    • Asim K. Duttaroy + 1 more
    • English
    New Developments in Redox Biology: Fundamental Roles in Health and Disease serves as a vital resource for understanding the profound impact of the redox system on human biology. In the book, readers are introduced to the intricate balance of oxidative stress, the delicate mechanisms of antioxidant defense, and their pivotal roles in cellular function. This book meticulously unpacks the connections between redox biology and the progression of health, aging, and disease, offering researchers and enthusiasts alike a window into these complex physiological processes.Aside from illuminating oxidative dynamics, this book delves into emerging trends, therapeutic potential, and the integration of redox principles in developing medical interventions, highlighting its relevance in advancing human health.

  • Primary Brain Tumors in Adults: Advances in Mechanistic Understanding, Evaluation, and Management

    • 1st Edition
    • Volume 166
    • English
    Primary Brain Tumors in Adults: Advances in Mechanistic Understanding, Evaluation, and Management, Volume 166 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Molecular drivers in primary brain tumor formation, Novel CSF pathways in the glioma (DIPG), Volumetric analysis in low grade gliomas and other advanced MR imaging techniques, Liquid biopsy in the diagnosis of primary brain tumors, Intraoperative imaging techniques to improve tumor detection, and much more.Additional chapters focus on Supramaximal resection in primary brain tumors, Radiotherapeutic approaches: IMRT, re-irradiation, Molecularly driven therapies in the treatment of primary brain tumors, and Changes in the immune microenvironment and immunotherapeutic strategies in the treatment of gliomas.

  • Myasthenia Gravis, Part A

    • 1st Edition
    • Volume 182
    • English
    Myasthenia Gravis, Part A, Volume 182 in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as the Structure of the NMJ and Neuromuscular Transmission, Neuromuscular Junction and the Complement System, Regulation of the Autoimmune Response, The Thymus, Antibodies/Subclasse... (IgG) and Antigens, Cell Models of MG, Mouse Models of EAMG and Passive Immunization, Epidemiology of Myasthenia Gravis, Special Populations: Juvenile, Early, Late, and Very Late-Onset, Blood and Digital Biomarkers in MG, Lambert-Eaton Myasthenic Syndrome, and Congenital Myasthenic Syndromes.

  • Sustainability in the Manufacturing of Pharmaceuticals

    • 1st Edition
    • Dimitrios A. Lamprou
    • English
    Sustainability in Pharmaceutical Manufacturing is a groundbreaking reference for the pharmaceutical industry. Currently lagging behind other manufacturing sectors, pharmaceutical production requires significant changes in areas such as manufacturing methods, waste management, packaging, and supply chain. This book compiles cutting-edge research from leading global experts, offering scientific insights and innovative strategies to revolutionize sustainability in pharmaceuticals. It explores the transformative potential of the circular economy, lifecycle management, and resource optimization for maximum efficiency and minimal environmental impact.The book delves into green chemistry, highlighting alternative solvents and methods for drug production. It emphasizes novel microfluidic and additive manufacturing techniques, utilizing bio-based sustainable polymers and materials. Chapters on greener drug discovery, development, and scaling processes provide the most current research at each production stage. This invaluable resource enables researchers in academia and industry to make informed choices, enhancing their manufacturing practices and shaping the future of sustainability in the pharmaceutical sector.

  • Neurotoxicity of Solvents

    • 1st Edition
    • Volume 14
    • English
    Neurotoxicity of Solvents, Volume Fourteen highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including the Effect of toluene on memory: A focus on humans, experimental models and treatment approaches, Neurotoxicological Mechanisms of Ethanol, Neurobehavioral Aspects and Methodology of Solvents, Organic solvents and neurodegenerative diseases: exploring a possible link, Neurotoxicity of propylene ethers, An ecotoxicological view on solvents neurotoxicity, and The olfactory system as a target of solvent toxicity.

  • Evapotranspiration in Agro-Ecosystems and Forestry

    Spatio-temporal Applications
    • 1st Edition
    • Suat Irmak
    • English
    Evapotranspiration in Agro-Ecosystems and Forestry: Spatio-temporal Applications presents the progress and advances made in terms of science and application of evaporation, transpiration, and evapotranspiration for various vegetation surfaces, water bodies, and bare soil under different soil and crop management (including different irrigation and tillage management) conditions. Sections on forest and wetlands evapotranspiration and grassland evaporative losses are included, as are the fundamentals of original Penman, Penman-Monteith, Shuttleworth-Wallace and ASCE-EWRI and FAO56 Penman-Monteith equations and their derivatives.The book is an excellent resource to better understand the progression and applications and dynamics of most recent evapotranspiration, evaporation and transpiration measurement and modeling technologies. Case studies will be provided in terms of how different technologies are currently deployed, how data are used for providing information and management decisions to the users.

  • Harmful Algal Blooms

    Environmental Factors and Molecular Mechanisms
    • 1st Edition
    • Senjie Lin
    • English
    Harmful Algal Blooms: Environmental Factors and Molecular Mechanisms offers a genomic and ecological perspective on harmful algal blooms, or HABs. The book provides the most updated and comprehensive knowledge crucial for understanding the causes of HABs while also synthesizing foundational knowledge with recent discoveries. Written by an expert in algal molecular ecology, it blends molecular biology, physiology, and ecology to examine how harmful algae thrive on environmental conditions like climate change. After introducing historical ecological models, the book delves into the influencing factors and underlying molecular mechanisms of HABs.Other sections explore an integrated molecular approach to incorporate energy, nutrients, defenses, and sexual reproduction (ENDs) as a resolution for HAB growth. This is an important resource for researchers and students in marine biology and ecology fields, as well as phycological and environmental studies.

  • Embracing the Complexity of Gender

    An Inclusive, Feminist, & Developmental Exploration
    • 1st Edition
    • Emily Keener
    • English
    Embracing the Complexity of Gender examines the heart of a modern gender revolution, exploring the dynamic and multifaceted nature of gender in contemporary society. Spurred by landmark events such as the legalization of same-sex marriage and the rise of transgender visibility, this revolution has ignited passionate debates and a heightened interest in understanding gender's complexities. From legal battles over all-gender bathrooms to corporate decisions challenging traditional gender norms, the discourse around gender has never been more vibrant or contentious. This book combines a developmental and intersectional feminist approach with accessible, engaging content.By including discussion questions and clear definitions of key terms, the book ensures that complex ideas are understandable for readers at all levels. Drawing on psychological evidence and theoretical perspectives, this book challenges the gender binary and emphasizes the importance of social justice and inclusion.

  • Yarrowia Lipolytica Yeast

    From Metabolic Engineering to Biotechnological Applications
    • 1st Edition
    • Mohamed Koubaa + 2 more
    • English
    Yarrowia Lipolytica Yeast: From Metabolic Engineering to Biotechnological Applications gathers all the information about the genetics, uses, extraction, purification, and applications of this non-conventional yeast, not just focusing on the genetics and metabolic engineering, nor on its biotechnological applications. Chapters cover the genetic modifications and techniques used to genetically modify Y. Lipolytica, fermentation conditions, various media used in biotechnological applications, and all value-added compounds that can be produced. Edited by the most renowned researchers of this yeast, this book is of great interest to industries t working on biofuel production or searching for environmentally-frie... natural alternatives for their chemically produced value-added compounds.

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