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Academic Press

  • Nonclinical Development of Biologics, Vaccines and Specialty Biologics

    • 2nd Edition
    • Lisa M. Plitnick + 1 more
    • English
    Nonclinical Development of Biologics, Vaccines and Specialty Biologics, Second Edition, is a complete reference devoted to the nonclinical safety assessment of novel biopharmaceuticals, vaccines, cell and gene therapies, and oncology therapeutics. Updated and revised, the new edition compares and contrasts these types of biologics with one another and with small molecule drugs, while incorporating the most current and essential international regulatory guidelines. This book discusses the different types of biologics, as well as early characterization strategies, principles of study design, nonclinical pharmacokinetics and pharmacodynamics, nonclinical assays, and regulatory guidelines. A coedited book with chapters authored by leading experts in the field, this comprehensive reference provides critical insights to all researchers involved in early through late-stage biologics.
  • PROTAC and similar technologies

    • 1st Edition
    • Volume 63
    • English
    Annual Reports on Medicinal Chemistry: PROTAC and similar technologies Volume 63 in this series Annual Reports on Medicinal Chemistry, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.
  • Surface Science and Advanced Functional Applications of Cellulose Composites

    • 1st Edition
    • Volume 38
    • Ming-Guo Ma + 1 more
    • English
    Surface Science and Advanced Functional Applications of Cellulose Composites, Volume 38 looks at cellulose composites in relation to surface science and applications. The book provides a comprehensive summary grounded in the surface chemistry and polymer physics of cellulose composites while also enabling readers to understand their history, status, and commercial challenges, and future potential using a range of case studies and examples. Other sections explore the applications of biomedical, antibacterial, water treatment, flexible electronic devices, energy storage, and sensing and review recent developments, problems, and potential developmental directions of cellulose composites.This book will appeal to chemists, chemical engineers, and materials scientists engaged in biomass, cellulose, nanocellulose, composites, surface science, and related applied biomedical, antibacterial, water treatment, flexible electronic device, and energy storage fields.
  • Leveraging Metaverse and Analytics of Things (AoT) in Medical Systems

    • 1st Edition
    • D. Jude Hemanth + 1 more
    • English
    Leveraging Metaverse and Analytics of Things (AoT) in Medical Systems explores the potential benefits and applications of emerging technologies such as metaverse and AoT in the field of healthcare. The book provides insights into how these technologies can be leveraged to improve the efficiency, effectiveness, and quality of medical systems. It explores the concept of metaverse and its potential applications in healthcare, including the use of virtual and augmented reality technologies for medical education, training, and simulation, as well as the development of immersive environments for patient care and therapy.The book also delves into the field of AoT, such as the use of wearable devices, smart sensors, and other connected technologies. Applications to monitor patient health, track medical outcomes, and inform clinical decision-making are covered. Integrating both technologies can help improve medical training, diagnosis, treatment, and patient outcomes through the use of virtual reality and real-time data analytics.
  • Empowering IoT with Big Data Analytics

    • 1st Edition
    • Mohamed Adel Serhani + 2 more
    • English
    Empowering IoT with Big Data Analytics provides comprehensive coverage of major topics, tools, and techniques related to empowering IoT with big data technologies and big data analytics solutions, thus allowing for better processing, analysis, protection, distribution, and visualization of data for the benefit of IoT applications and second, a better deployment of IoT applications on the ground. This book covers big data in the IoT era, its application domains, current state-of-the-art in big data and IoT technologies, standards, platforms, and solutions. This book provides a holistic view of the big data value-chain for IoT, including storage, processing, protection, distribution, analytics, and visualization.Big data is a multi-disciplinary topic involving handling intensive, continuous, and heterogeneous data retrieved from different sources including sensors, social media, and embedded systems. The emergence of Internet of Things (IoT) and its application to many domains has led to the generation of huge amounts of both structured and unstructured data often referred to as big data.
  • Fungal Biotechnology

    Industrial Applications and Market Potential
    • 1st Edition
    • Ram Sarup Singh + 1 more
    • English
    Fungal Biotechnology: Industrial Applications and Market Potential provides a comprehensive and holistic review on the uses of filamentous fungi in food, agriculture, and pharmaceutical industries. In addition to genetic and metabolic engineering approaches for heterologous proteins production in fungi, the book focuses on fungi as a source of bioactive compounds like enzymes, polysaccharides, alkaloids, glycoproteins, and phytohormones. It describes recent trends in the use of fungi for solid waste management and its subsequent conversion into value added products.As a complete guide on the broad uses of microfungi in different industrial sectors while maintaining a sustainable environment, this book is a beneficial resource for students, researchers, and scientists as an effective means of imparting knowledge on the current trends and future perspectives in the field of fungal biotechnology.
  • Diagnosing Musculoskeletal Conditions using Artificial Intelligence and Machine Learning to Aid Interpretation of Clinical Imaging

    • 1st Edition
    • Rakesh Kumar + 3 more
    • English
    Bone deformations can lead to musculoskeletal disorders and negatively impact on individual quality of life. Early and accurate detection of bone deformation is crucial for effective medical intervention. Diagnosing Musculoskeletal Conditions Using Artificial Intelligence and Machine Learning to Aid Interpretation of Clinical Imaging outlines a comprehensive approach that integrates Artificial Intelligence (AI) and Machine Learning (ML) techniques to identify bone deformations promptly and accurately. By leveraging advanced image analysis and pattern recognition, this approach aims to revolutionize the field of orthopedic diagnostics. This book covers challenges, technologies, applications, and future trends of AI and ML in Bone Deformation, addressing advanced and innovative techniques, frameworks, methodologies, and practical implementations of machine learning to get early predictions of Bone deformation. Written by experts in the field for researchers, surgeons, students, and instructors interested in musculoskeletal conditions.
  • Annual Reports on Computational Chemistry

    • 1st Edition
    • Volume 20
    • English
    Annual Reports on Computaional Chemistry, Volume 20 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.
  • Health and Climate Change

    Unraveling the Connections
    • 1st Edition
    • Saroj Pachauri + 2 more
    • English
    Health and Climate Change: Unraveling the Connections researches the linkages between climate change and human health as reported from Mexico, the UK, USA, India, Bangladesh, Cameroon, Nigeria, and Cameroon. The book's chapters cover the multidimensional impacts of climate change on various aspects such as habitability, biodiversity, natural resources, and human health. This information from developed and developing countries will be of immense interest to the global audience of researchers, activists, governments, and others.Climate change, one of the greatest challenges of the 21st century, has serious adverse effects on human health. Extreme climate events increase mortality and morbidity, the prevalence of water- and vector-borne diseases, malnutrition, and respiratory diseases. Climate change has serious effects on mental health. Mental health is impacted directly and indirectly resulting in mental illnesses and suicidal mortality. Global heating, due to the increasing greenhouse effect, has disturbed the energetic balance of the Earth and destroyed its fragile climate. It is creating an atmospheric imbalance with toxins that are affecting the human nervous system and, thereby, impacting health.
  • Osteomyelitis and Discitis of the Spine

    A Guide for the Management of Infectious Etiology of the Vertebral Column and Neurological Components
    • 1st Edition
    • Dia R Halalmeh + 1 more
    • English
    Osteomyelitis and Discitis of the Spine: A Guide for the Management of Infectious Etiology of the Vertebral Column and Neurological Components examines these spinal conditions and provides readers with the most appropriate management plans, including surgical treatment together with its indications. This book guides spine neurosurgeons and others when choosing the optimal surgical approach for their patients, shedding light on current advances in surgical techniques used in the management of vertebral osteomyelitis and discitis, particularly minimally invasive spine approaches.With authors representing diverse specialties, chapters reflect current clinical and surgical practice and discuss pathophysiology and pain management and rehabilitation. The book begins with related anatomy and extends to post-management rehabilitation and pain control, including a chapter dedicated to pediatric patients and their differing causative organisms, etiology, diagnostic modalities, and pathophysiology. This reference will provide increased awareness of potential spinal infection, facilitating multidisciplinary management plans, improving patient safety and outcomes, and enabling early intervention alternatives that improve patient outcomes and long-term quality of life.