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Elsevier

Academic Press

  • Brains and Machines: Towards a unified Ethics of AI and Neuroscience

    • 1st Edition
    • Volume 7
    • English
    Brains and Machines: Towards a unified Ethics of AI and Neuroscience provides a comprehensive overview of concepts and ethical issues at the intersection of two emerging technological trends in the 21st century: AI and neurotechnology. In line with recent advances across both fields, debates about philosophical, ethical, regulatory and social issues raised by neuroscience and AI have considerably expanded in the past decade. Yet, despite many intersections and fruitful interactions between the two scientific domains, ethical debates about neuroscience and AI have mostly moved in parallel. This volume assembles voices from various disciplines to provide a more unified view and offer novel perspectives on two complementary lines of discourse. The volume provides scientific background by outlining the state of the art of applying AI in the field of neuroscience and discussing instances where findings and debates from neuroscience provide cues and inspiration to the study of AI. Based on this background, the book then addresses conceptual frameworks, identifies ethical challenges at the intersection of neuroscience and AI, and highlights challenges and opportunities of finding common ground in interdisciplinary settings.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 81
    • English
    Advances in Organometallic Chemistry, Volume 81 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Specific chapters cover Recent Advances in the Catalytic Applications of NHC-Early Abundant Metals (Fe, Mn, Co) Complexes, A Guide to Non-Carbonyl, Non-Isocyano Organometallic Chemistry of Technetium-99 from Discovery to 2023, and Cyclopentadienyl, Amidinate (CPAM) Complexes of Groups 4 - 6 Transition Metals.

  • Regulatory T cells and Autoimmune Diseases

    • 1st Edition
    • Mitesh Kumar Dwivedi + 1 more
    • English
    Regulatory T Cells and Autoimmune Diseases addresses recent findings concerning the role of Tregs in the pathogenesis of autoimmune diseases as well as their therapeutic applications. In particular, this book deals with various Treg-based mechanisms that can lead to autoimmune disease and covers different aspects linking Tregs with autoimmune mechanisms involved in disease development by discussing animal models and human studies.This book specifically focuses on Treg-based therapeutics and their targets to manage all known autoimmune rheumatic, central nervous system, bowel, liver, thyroid, kidney, myopathic, skin, blood and blood vessel, and eye diseases and aims to provide a must-have reference for designing therapeutic strategies to treat these autoimmune diseases. Additionally, this book covers vaccine-induced effects on the functioning of Tregs and development of CAR Treg therapy for autoimmune diseases and concludes with current challenges and future prospects of Treg-based therapeutics. This book is carefully designed to meet the requirements of both basic and advanced researchers in the area and provide new dimensions and insight into regulatory T cells’ role in autoimmune disease pathogenesis and therapy.

  • New Approach for Drug Repurposing Part A

    • 1st Edition
    • Volume 205
    • English
    New approach for drug repurposing represents drug discovery and development which is a tedious process that requires 10-15 years of time, investments up to $1-2 billion, and have high risk of failure to enter into market for clinical applications. As the drugs has to pass through number of developmental phase, the likelihood for a drug to be approved from phase I clinical trial to United States of Food and Drug Administration (USFDA) approval is less than 10%. More than 90% of drugs failed in due to toxicity, efficacy and clinical trials. Drug repurposing is one of the roadway to accelerating drug discovery and development for treating disease and thus to providing better quality of life. This volume covers an overview of drug repurposing, novel methods, mechanism of action, lab on chip for drug repurposing, computational biology, system biology, artificial intelligence and machine learning for drug repurposing, target identification, target mining, high throughput drug screening, clinical trial of repurposed drug, repurposed biologics, and regulatory consideration and intellectual property right of repurposed drug. This volume highlights a number of aspects of the drug repurposing that can help the basic understanding of students, researchers, clinicians, entrepreneurs, and stakeholders to perform their research with great interest.

  • Advances in Artificial Intelligence

    Biomedical Engineering Applications in Signals and Imaging
    • 1st Edition
    • Kunal Pal + 2 more
    • English
    Artificial intelligence in healthcare has become one of the best assisting techniques for clinicians in proper diagnosis and surgery. In biomedical applications, artificial intelligence algorithms are explored for bio-signals, such as electrocardiogram (ECG/EKG), electrooculogram (EOG), electromyogram (EMG), electroencephalogram (EEG), blood pressure, heart rate, and nerve conduction, and for bio-imaging modalities, such as computed tomography (CT), cone-beam computed tomography (CBCT), and MRI (magnetic resonance imaging). Advancements in artificial intelligence and big data have increased the development of innovative medical devices in healthcare applications. Advances in Artificial Intelligence: Biomedical Engineering Applications in Signals and Imaging provides an overview of arti­ficial intelligence in biomedical applications, including both bio-signals and bio-imaging modalities. The chapters contain a mathematical formulation of algorithms and their applications in the biomedical ­ eld, including case studies. Biomedical engineers, advanced students, and researchers can use this book to apply their knowledge in artificial intelligence-based processes to biological signals, implement mathematical models and advanced algorithms, and develop AI-based medical devices.

  • Pharmacology in Drug Discovery and Development

    Understanding Drug Response
    • 3rd Edition
    • Terry P. Kenakin
    • English
    Pharmacology in Drug Discovery and Development: Understanding Drug Response, Third Edition is an introductory resource that illustrates how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems. New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization.The updates to the Third Edition include a new section converting “descriptive” data into “predictive” data through comparison to mathematical models, expansion on enzymes, drug metabolites and drug–drug interactions, and two new chapters. The newly developed companion website hosts further educational resources to complement the book. As in previous editions, this new edition includes numerous valuable chapter summaries, detailed references, practical examples, and case studies throughout.

  • Banana Peels Valorization

    Sustainable and Eco-friendly Applications
    • 1st Edition
    • Mejdi Jeguirim + 1 more
    • English
    Banana Peels Valorization: Sustainable and Eco-friendly Applications provides a global overview of world production, physicochemical and microbiological characteristics of Banana Peels and the various pathways for their valorization, considering the advantages, disadvantages and factors impacting on each way of valorization. Each chapter deals with sustainable applications based on the sector category. Such structure helps the audience from a specific field to easily identify the specific application. Successful case study of a banana processing by-products valorization is also presented. Written by a team of interdisciplinary experts, this is the ultimate valuable resource for agricultural or food engineers who work in the banana groves and in the banana processing industry, and also for Researchers working in correlated areas of food, environmental and energy fields.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 127
    • English
    Advances in Applied Microbiology, Volume 127 continues the comprehensive reach of this widely read and authoritative review source in microbiology where users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

  • Application of Gellan Gum as a Biomedical Polymer

    • 1st Edition
    • Amit Kumar Nayak + 1 more
    • English
    Application of Gellan Gum as a Biomedical Polymer details key topics and fundamental aspects of gellan gum and its biomedical applications in drug delivery, proteins and peptides delivery, cell delivery, tissue engineering, wound dressings and enzyme immobilizations in developing high quality products. Sections introduce gellan gum, its source, production and gelation mechanism, discuss biomedical materials, and provides ways it can be used for biomedical applications. The book also examines the used of gellan gum as pharmaceutical excipients for drug delivery. Future developments and challenges round out the book’s coverage.With contributions for an international group of experts, this book is a useful reference for scientists, researchers and those in industry engaged in biomedical product development using natural polysaccharides.

  • Nucleic acid associated mechanisms in immunity and disease

    • 1st Edition
    • Volume 161
    • English
    Advances in Immunity volume 161 highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

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