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Elsevier

Academic Press

  • Tritium Technologies for Thermonuclear Fusion Reactors

    • 1st Edition
    • Alexander Perevezentsev + 1 more
    • English
    Tritium Technologies for Thermonuclear Fusion Reactors summarizes the most recent research and practice in tritium technologies for the processing of hydrogen isotopes in fuel cycles. Authors Dr. Perevezentsev and Professor Rozenkevich combine their wealth of first-hand experience to present this comprehensive guide which promotes the best radiation protection practices and a more sustainable way to produce power in a thermonuclear reactor plant. Applicable to both magnetic and inertial confinements of plasma, this book covers tritium processing systems, tritium recovery from the plasma chamber, and various safety systems devoted to lessening the impact on the public and environment. The readers are also led through various modeling techniques, such as the separation of hydrogen isotopes, and the detritiation of liquid and gaseous streams in dynamic and steady state operation modes. This book is a practical guide which includes various case studies and examples which will help solidify the reader’s learning. It combines the latest research of tritium technologies with applications for fusion nuclear reactors, and includes solutions and directions for the resolution of various common challenges faced. Engineers, researchers, and students of tritium technologies, fusion energy, and nuclear power generation will gain a detailed and integrated understanding of how tritium can be used within a nuclear setting, for cleaner and more efficient power generation.

  • Methods in iPSC Technology

    • 1st Edition
    • Alexander Birbrair
    • English
    The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Methods in iPSC Technology, Volume 9 addresses the different methods used for induced pluripotent stem cell (iPSC) formation, maintenance, expansion, and differentiation. The ability to reprogram different cell types to iPSCs offers an opportunity to generate pluripotent patient-specific cell lines that can help in the understanding of multiple human disorders. This volume addresses a variety of current methods used in the generation and manipulation of iPSCs, such as magnetic nanoparticles, piggyBac vectors, lentiviral vectors, bioscaffolds, somatic cell nuclear transfer, CRISPR/Cas9, bacteria, and much more. This volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and organ transplantation and is contributed by world-renowned authors in the field.

  • Current Progress in iPSC-derived Cell Types

    • 1st Edition
    • Alexander Birbrair
    • English
    The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Current Progress in iPSC-derived Cell Types, Volume 10 addresses how induced pluripotent stem cells can be differentiated into different cell types. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how research of induced pluripotent stem cells can be reprogrammed to develop new treatment technologies in regenerative medicine. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field.

  • Apoptosis in Health and Disease - Part B

    • 1st Edition
    • Volume 126
    • Rossen Donev
    • English
    Apoptosis in Health and Disease - Part B, Volume 126 in the Advances in Protein Chemistry and Structural Biology focuses on apoptotic responses in numerous conditions - from bacterial and parasite infections, to pathological states such as oxidative stress, pulmonary hypertension, and different cancer types, etc. In addition, the book provides therapeutic strategies for targeting apoptosis. These new advanced understandings are playing a major influence in drug discovery and the introduction of new therapies that target the cell death process. Apoptosis, or programmed cell death, is the mechanism by which cells die either physiologically or pathologically. Vast research in apoptosis has advanced our understanding of basic physiological and pathological processes occurring in cells, organs and organisms, and its role in a number of diseases.

  • Assessments, Treatments and Modeling in Aging and Neurological Disease

    The Neuroscience of Aging
    • 1st Edition
    • Colin R. Martin + 2 more
    • English
    Assessments, Treatments and Modeling in Aging and Neurological Disease: The Neuroscience of Aging is a comprehensive reference on the diagnosis and management of neurological aging and associated disorders. The book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the interactions between genetics, epigenetics and other micro-environmental processes. It also examines pharmacological and non-pharmacological interventions of age-related conditions that affect the brain, including Alzheimer’s, stroke and multiple sclerosis.

  • Lanzkowsky's Manual of Pediatric Hematology and Oncology

    • 7th Edition
    • Jonathan D. Fish + 2 more
    • English
    Lanzkowsky’s Manual of Pediatric Hematology and Oncology, Seventh Edition remains the go-to clinical manual for the treatment and management of childhood cancers and blood disorders. It is a comprehensive book on patient management, replete with algorithms and flow diagrams, and includes a new section on vascular anomalies. Reflecting the considerable advances in the treatment and management of hematologic and oncologic diseases in children, the seventh edition of this successful clinical manual is entirely updated to incorporate all current treatment protocols, new drugs, and management approaches. Its concise and easy-to-read format, again, enables readers to make accurate diagnoses and treatment decisions without having to reference larger medical textbooks.

  • Mathematica by Example

    • 6th Edition
    • Martha L. Abell + 1 more
    • English
    Mathematica by Example, Sixth Edition is an essential resource for the Mathematica user, providing step-by-step instructions on achieving results from this powerful software tool. The book fully accounts for the changes to functionality and visualization capabilities and accomodates the full array of new extensions in the types of data and problems that Mathematica can immediately handle, including cloud services and systems, geographic and geometric computation, dynamic visualization, interactive applications and other improvements. It is an ideal text for scientific students, researchers, and aspiring programmers seeking further understanding of Mathematica. Written by seasoned practitioners with a view to practical implementation and problem-solving, the book's pedagogy is delivered clearly and without jargon using representative biological, physical and engineering problems. Code is provided on an ancillary website to support the use of Mathematica across diverse applications and subject areas.

  • Gigantism and Acromegaly

    • 1st Edition
    • Constantine A. Stratakis
    • English
    Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim’s appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies.

  • Factors Affecting Neurological Aging

    Genetics, Neurology, Behavior, and Diet
    • 1st Edition
    • Colin R. Martin + 2 more
    • English
    Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with neurological aging and associated disorders. This book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the physiological, behavioral, molecular, and cellular features of neurological aging. Finally, this comprehensive resource examines the use of animal modeling of aging and neurological disease.

  • Amphibian Models of Development and Disease

    • 1st Edition
    • Volume 145
    • English
    Amphibian Models of Development and Disease, Volume 145 in the Current Topics in Developmental Biology series, highlights new advances in the field written by an international board of experts. New chapters in this release include Building a ciliated epithelium: Transcriptional regulation and radial intercalation of multiciliated cells, Biomechanics of Amphibian Morphogenesis, Planar cell polarity during neural tube closure, Xenopus neural crest and its relevance to human disease, Endoderm organogenesis, From egg to embryo in marsupial frogs, Evo-devo lessons from the analysis of Xenopus genomes, Transcriptional regulation during zygotic genome activation, Proteomics and metabolomics for cell lineage analysis in frog embryos, and more.

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