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Academic Press

  • Role of Biomarkers in Cancer Diagnosis and Therapeutics

    • 1st Edition
    • Sushama Talegaonkar + 2 more
    • English
    Role of Biomarkers in Cancer Diagnosis and Therapeutics offers a thorough exploration of the critical roles biomarkers play in cancer detection, diagnosis, monitoring, and therapy. Sections focus on established and emerging biomarkers like PSA and CEA, detailing their biochemical characteristics and clinical relevance, and examining metabolic pathways utilized by cancer cells, highlighting key enzymes and their therapeutic potential. The final part pf the book discusses innovative strategies targeting cell cycle checkpoints and DNA repair mechanisms, including synthetic lethality through PARP inhibitors. This essential resource provides researchers and clinicians with insights into novel metabolic targets and cutting-edge treatment strategies.By addressing current applications and future challenges, including the integration of AI and multi-omics approaches, the book equips readers with actionable knowledge to advance personalized cancer care and navigate the dynamic landscape of oncology.
  • Unlocking the Secrets of Extracellular Vesicles and Exosomes

    A Journey into the Cutting-Edge Frontier of Cellular Communication
    • 1st Edition
    • Chandrashekhar Singh + 4 more
    • English
    Unlocking the secrets of extracellular vesicles and exosomes: A journey into the cutting-edge frontier of cellular communication provides a comprehensive overview of the latest advances and research on extracellular vesicles (EVs) and exosomes. The book begins with a historical introduction to the field and how this has evolved since EVs were first observed, before exploring their cellular mechanisms and approaches to study their isolation, characterization, and function. It then delves into exosomes in health and disease, considering their role across cancer, regenerative medicine, neurological disorders, and metabolic disorders, highlighting their potential as biomarkers for disease diagnosis. The book moves on to discuss cutting-edge technology for the engineering of EVs and exosomes, considering how the integration of AI, machine learning, and nanotechnology can be utilized to expand the therapeutic capabilities of EV and exosome-based applications. It then closes with chapters covering novel applications in nutraceutical and cosmetic production, and a look towards the future potential of EVs and exosomes. Unlocking the secrets of extracellular vesicles and exosomes offer a thorough exploration of EV and exosome research, covering various dimensions from basic science to clinical applications and future perspectives. It is an ideal guide for researchers working across a diverse range of disciplines, including cell biology, molecular biology, biotechnology, therapeutics, and biomedicine.
  • Immunological Aspects of Preterm Birth

    • 1st Edition
    • Volume 4
    • Irina Burd MD
    • English
    Immunological Aspects of Preterm Birth, a volume in the Reproductive Immunology book series, bridges reproductiveimmunolo... of preterm birth to subtypes, phenotypes, and bedside prevention and treatment. This book reviews therole of the different immune mechanisms during pregnancy leading to preterm birth and fetal programming effects thatare connected to maternal immune activation. This book also discusses immune cells and their products, cytokines andchemokines, as central for the success of the pregnancy, from the process of implantation to parturition and the effects ofthe changes on fetal programming.While our knowledge on the role of immune cells and the inflammatory process in preterm birth has grown exponentiallyin the last 10 years, connecting basic science to clinical science and development of new therapeutics has not progressedas rapidly. This book assists researchers in understanding the basic immunologic mechanisms and inflammatory processesassociated with preterm birth and fills an urgent need for the development of therapeutics in this space.
  • A Complete Guide to Hysteroscopic Myomectomy

    • 1st Edition
    • Rahul Manchanda + 2 more
    • English
    A Complete Guide to Hysteroscopy Myomectomy provides an evidence-based, comprehensive treatise on hysteroscopic myomectomy, a valuable option for treating uterine fibroids that offers a less invasive alternative to traditional surgeries like hysterectomies and laparotomies. This complete guide helps readers master how to diagnose and select the most appropriate strategy of treatment, describing all aspects of each strategy and applying the knowledge in different clinical settings. This is an essential reference for anyone in the research and medical field. It's also ideal for patients who want to understand the procedure's benefits, indications, and recovery process to make informed decisions about their treatment options.
  • Artificial Intelligence in Gastrointestinal Cancers

    • 1st Edition
    • Ganji Purnachandra Nagaraju + 2 more
    • English
    Artificial Intelligence in Gastrointestinal Cancers examines the transformative impact of AI technologies on diagnosing and treating gastrointestinal malignancies. This book explores how advanced algorithms, particularly deep learning models, enhance the analysis of medical imaging, including endoscopic, MRI, and CT scans, facilitating earlier and more accurate identification of cancers such as esophageal, stomach, colorectal, and pancreatic cancers. The content covers AI's multifaceted applications, from improving diagnostic accuracy to personalizing treatment strategies based on genomic and clinical data. It discusses how machine learning predicts patient outcomes and optimizes treatment plans while also addressing AI's role in accelerating drug discovery and clinical trials. For an academic audience, this book provides crucial insights into AI's current and future applications in GI oncology. Readers gain a comprehensive understanding of AI diagnostic tools and personalized treatment strategies, equipping researchers and clinicians with the knowledge to leverage these advancements for improved patient care and outcomes in gastrointestinal cancers.
  • Handbook of Microalgae-Based Processes and Products

    Fundamentals and Advances in Energy, Food, Feed, Fertilizer, and Bioactive Compounds
    • 2nd Edition
    • Eduardo Jacob-Lopes + 3 more
    • English
    The Handbook of Microalgae-Based Processes and Products provides a complete overview of all aspects involved in the production and utilization of microalgae resources at commercial scale. Divided into five parts (foundations of microalgae research, microalgae cultivation and downstream processing, microalgae compounds and their multifaceted applications, engineering, bioeconomy, and sustainability in microalgae-based systems, and emerging technologies and breakthroughs), the book explores the microbiological, physiological, and metabolic aspects of microalgae, microalgal production systems, wastewater treatment and bioremediation using microalgae, COâ‚‚ capture, microalgae harvesting techniques, and extraction of biomolecules from microalgae. It covers a wide range of microalgal compounds and applications of commercial relevance, including food ingredients, proteins and bioactive peptides, polysaccharides, lipids and fatty acids, pigments, sterols, industrial enzymes, volatile organic compounds, and bioactive molecules. The book also discusses applications in food and feed, human health, agriculture, cosmeceuticals, bioplastics, and biofuels, as well as innovative uses such as cultured meat production and photosynthetic materials for biomedical applications. Moreover, it presents and discusses engineering and sustainability tools applied to microalgae biotechnology, such as process integration, process intensification, exergy analysis, industrial-scale production strategies, microalgal biorefineries, and the role of microalgae technologies in the circular bioeconomy and sustainable development.The coverage of a broad range of potential microalgae processes and products in a single volume makes this handbook an indispensable reference for engineering researchers in academia and industry in the fields of bioenergy, sustainable development, and high-value compounds from biomass, as well as graduate students exploring those areas. Engineering professionals in bio-based industries will also find valuable information here when planning or implementing the use of microalgal technologies.
  • Microbial Stress Biology

    • 1st Edition
    • Samiksha Joshi + 4 more
    • English
    Microbial Stress Biology offers a comprehensive understanding of the adaptation strategies of microbes at the biochemical and molecular level in response to stressful conditions, while also detailing the molecular mechanisms that enable microbial organisms to survive and persist under these adverse circumstances. The book discusses a wide array of topics related to microbial adaptation, covering fundamental biological responses to stress, microbial adaptations at cellular, genomic, and proteomic levels, as well as specific adaptations and regulations to various environmental stress factors such as pH fluctuations, chemicals, and extreme thermal conditions.Sections also highlight the application of omics technology and predictive modeling in understanding microbial stress biology for various fields, including biotechnology, medicine, bioremediation, and industrial processes. This book is an informative resource for those in microbiology, molecular biology, biotechnology, and other related fields who are searching for a better understanding of how microbes are able to sense and respond to distinct stressors at both molecular and cellular levels.
  • AI, Blockchain and Social Network on Urban Crisis Management: Leveraging Emerging Technologies for Disaster Response and Resilience in Smart Cities

    • 1st Edition
    • Volume 142
    • English
    AI, Blockchain and Social Network on Urban Crisis Management: Leveraging Emerging Technologies for Disaster Response and Resilience in Smart Cities, Volume 142 in the Advances in Computers series, examines how cutting-edge digital technologies are reshaping disaster preparedness and response. This volume highlights the convergence of artificial intelligence, blockchain, and social network analysis to predict, prevent, and manage urban crises. Chapters explore Nutrient Recovery from Livestock Effluent in a Circular Economy Approach, Leveraging Artificial Intelligence for Deforestation Monitoring and Conservation in the Colombian Amazon, Experimental and Theoretical Investigation of Diffusion in Hydrocarbon-Based Dense Fluids for Enhanced Oil Recovery, and much more.Additional chapters cover Navigating the Complexities: Challenges, Weaknesses, and Hurdles in Integrating AI, Blockchain, and Social Networks for Urban Crisis Management, Educating Europe's Guardians: Ethical AI and Emerging Technologies in Law Enforcement Training for Urban Crisis Management, The Intersection of AI, Blockchain, and Social Networks in Urban Crises Management, Application of Graph Theory in Disaster Management for Efficient Handling and Mobilizing of Resources and Logistics, Analyzing the Role of Social Networks in Urban Crisis Management through Citizen Participation and Smart Technological Deployment, and many more important and timely topics.
  • The Itch Spectrum

    • 1st Edition
    • Xinzhong Dong + 2 more
    • English
    The Itch Spectrum: The Neurological and Immunological Basis of Itch and Dermatological Disorders covers the latest research on the itch signalling pathway from the skin to the brain. With a multidisciplinary approach, this book will cover the mechanisms underlying the sensation of itch from the fields of neuroscience, immunology, genetics, and dermatology as they have intersected in the study of one somatosensory system. The purpose of this comprehensive reference is to summarize the revelatory discoveries in the field of itch and provide a comprehensive overview of what is known about this remarkable sensation and how various pathologies contribute to chronic pruritis.
  • Plant Proteins

    Nutritional Aspects and Processing Applications
    • 1st Edition
    • Nisar Ahmad Mir + 1 more
    • English
    Plant Proteins: Nutritional Aspects and Processing Applications covers various methods used to extract and purify plant proteins for nutrition, health, and new product development. The book identifies techniques and modifications such as fermentation, radiation, and ball-milling to characterize plant protein structure and functionality. Readers will learn how each method serves a different purpose in enhancing flavor, texture, and/or shelf-life. A special focus on plant-based meat is discussed, along with insights on how plant-based proteins effect digestive wellness and the microbiome. Additional sections address the nano-reduction of plant-based proteins and their role in the delivery of different bioactive compounds and health benefits.