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Elsevier

Academic Press

  • Liquid Acquisition Devices for Advanced In-Space Cryogenic Propulsion Systems

    • 1st Edition
    • Jason William Hartwig
    • English
    Liquid Acquisition Devices for Advanced In-Space Cryogenic Propulsion Systems discusses the importance of reliable cryogenic systems, a pivotal part of everything from engine propulsion to fuel deposits. As some of the most efficient systems involve advanced cryogenic fluid management systems that present challenging issues, the book tackles issues such as the difficulty in obtaining data, the lack of quality data and models, and the complexity in trying to model these systems. The book presents models and experimental data based on rare and hard-to-obtain cryogenic data. Through clear descriptions of practical data and models, readers will explore the development of robust and flexible liquid acquisition devices (LAD) through component-level and full-scale ground experiments, as well as analytical tools. This book presents new and rare experimental data, as well as analytical models, in a fundamental area to the aerospace and space-flight communities. With this data, the reader can consider new and improved ways to design, analyze, and build expensive flight systems.

  • Fossil Parasites

    • 1st Edition
    • Volume 90
    • Tim Littlewood + 1 more
    • English
    Fossil Parasites, the latest edition in the Advances in Parasitology series established in 1963, contains comprehensive and up-to-date reviews on all areas of interest in contemporary parasitology, including medical studies of parasites of major influence, such as plasmodium falciparum and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which help to shape current thinking and applications. Parasitism is a dominant life history strategy and we know it has existed for millions of years. Detecting parasitism in the fossil record is problematic because we rarely see direct evidence and usually must rely on indirect evidence to infer its existence. This unique volume takes a broad and systematic view of direct and indirect evidence for parasitism in the fossil record.

  • Axons and Brain Architecture

    • 1st Edition
    • Kathleen Rockland
    • English
    Several excellent monographs exist which deal with axons. These, however, focus either on the cellular and molecular biology of axons proper or on network organization of connections, the latter with only an incidental or abstract reference to axons per se. Still relatively neglected, however, is the middle ground of terminations and trajectories of single axons in the mammalian central nervous system. This middle level of connectivity, between networks on the one hand and local, in vitro investigations on the other, is to some extent represented by retrograde tracer studies and labeled neurons, but there have so far been many fewer of the complementary anterograde studies, with total visualization of the axonal arborization. The present volume brings together in one source an interrelated treatment of single axons from the perspective of microcircuitry and as substrates of larger scale organization (tractography). Especially for the former area - axons in microcircuitry - an abundance of published data exists, but these are typically in specialty journals that are not often accessed by the broader community. By highlighting and unifying the span from microcircuitry to tractography, the proposed volume serves as a convenient reference source and in addition inspires further interactions between what currently tend to be separate communities. The volume also redresses the imbalance between in vitro/local connectivity and long-distance connections. Focusing on mammalian systems, Part 1 of this book is devoted to anatomical investigations of connections at the single axon level, drawing on modern techniques and classical methods from the 1990s. A particular emphasis is on broad coverage of cortical and subcortical connections from different species, so that common patterns of divergence, convergence, and collateralization can be easily appreciated. Part 2 addresses mechanisms of axon guidance, as these seem particularly relevant to pathways and branching patterns. Part 3 covers axon dynamics and functional aspects; and Part 4 focuses on tractography, notably including comparisons between histological substrates and imaging.

  • Advances in Tuna Aquaculture

    From Hatchery to Market
    • 1st Edition
    • Daniel Benetti + 2 more
    • English
    Advances in Tuna Aquaculture: From Hatchery to Market provides detailed overviews on the current status of tuna fisheries, fattening, and farming practices, as well as advances in closed-cycle tuna aquaculture. Contributors are renowned scientists, internationally recognized as authorities in their fields. This book addresses all basic and applied aspects of tuna aquaculture, presenting and discussing the global status of tuna fisheries, reproduction, broodstock management, spawning, larval rearing and early developmental stages including nursery and grow out methods. It presents incorporates the most comprehensive and updated data, statistics, and trends in tuna fisheries and aquaculture, covering and addresses a variety of topics ranging fromfrom endocrinology, nutrition, diseases, and genetics to economics and markets. It covers describes recent up-to-date progress on tuna aquaculture and hatchery development. It also provides a synopsisn overview of the challenges presently confronted by tuna aquaculturists,facin... tuna aquaculture and and offers innovative views on the challengesbottle-nec... issues faced by the industry with the current shift from fisheries to fattening to closed-cycle aquaculture. This is the first book to encompass all aspects related to the tuna aquaculture industry, and merges them into a state-of-the-art compendium that will serve as seminal reference for students, researchers, and professionals working with tuna biology, fisheries, and aquaculture worldwide.

  • Computational and Statistical Methods for Analysing Big Data with Applications

    • 1st Edition
    • Shen Liu + 3 more
    • English
    Due to the scale and complexity of data sets currently being collected in areas such as health, transportation, environmental science, engineering, information technology, business and finance, modern quantitative analysts are seeking improved and appropriate computational and statistical methods to explore, model and draw inferences from big data. This book aims to introduce suitable approaches for such endeavours, providing applications and case studies for the purpose of demonstration. Computational and Statistical Methods for Analysing Big Data with Applications starts with an overview of the era of big data. It then goes onto explain the computational and statistical methods which have been commonly applied in the big data revolution. For each of these methods, an example is provided as a guide to its application. Five case studies are presented next, focusing on computer vision with massive training data, spatial data analysis, advanced experimental design methods for big data, big data in clinical medicine, and analysing data collected from mobile devices, respectively. The book concludes with some final thoughts and suggested areas for future research in big data.

  • Atlas of the Human Brain

    • 4th Edition
    • Juergen K Mai + 2 more
    • English
    The fourth edition of Atlas of the Human Brain presents the anatomy of the brain at macroscopic and microscopic levels, featuring different aspects of brain morphology and topography. This greatly enlarged new edition provides the most detailed and accurate delineations of brain structure available. It includes features which assist in the new fields of neuroscience – functional imaging, resting state imaging and tractography. Atlas of the Human Brain is an essential guide to those working with human brain imaging or attempting to relate their observations on experimental animals to humans. Totally new in this edition is the inclusion of Nissl plates with delineation of cortical areas (Brodmann’s areas), the first time that these areas have been presented in serial histological sections.

  • Recent Advances in Microbial Oxygen-Binding Proteins

    • 1st Edition
    • Volume 67
    • English
    This latest volume in Advances in Microbial Physiology continues the long tradition of topical and important reviews in microbiology.

  • Drug Discovery in Cancer Epigenetics

    • 1st Edition
    • Gerda Egger + 1 more
    • English
    Drug Discovery in Cancer Epigenetics is a practical resource for scientists involved in the discovery, testing, and development of epigenetic cancer drugs. Epigenetic modifications can have significant implications for translational science as biomarkers for diagnosis, prognosis or therapy prediction. Most importantly, epigenetic modifications are reversible and epigenetic players are found mutated in different cancers; therefore, they provide attractive therapeutic targets. There has been great interest in developing and testing epigenetic drugs, which inhibit DNA methyltransferases, histone modifying enzymes or chromatin reader proteins. The first few drugs are already FDA approved and have made their way into clinical settings. This book provides a comprehensive summary of the epigenetic drugs currently available and aims to increase awareness in this area to foster more rapid translation of epigenetic drugs into the clinic.

  • Translating Regenerative Medicine to the Clinic

    • 1st Edition
    • Jeffrey Laurence + 2 more
    • English
    Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin. Pedagogically, the book concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. It promotes cross-disciplinary communication between the sub-specialties of medicine, but remains unified in theme by emphasizing recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole. Volumes in the series include Translating Gene Therapy to the Clinic, Translating Regenerative Medicine to the Clinic, Translating MicroRNAs to the Clinic, Translating Biomarkers to the Clinic, and Translating Epigenetics to the Clinic.

  • Translational Immunology

    Mechanisms and Pharmacologic Approaches
    • 1st Edition
    • Seng-Lai Tan
    • English
    Translational Immunology: Mechanisms and Pharmacologic Approaches highlights and summarizes the most important advances in human immunology, clinical translations, new tools to analyze therapeutic targets, and new pharmacological approaches for autoimmunity, inflammatory disorders, and cancer. The book is an essential resource for those seeking to understand the potential translational applications of burgeoning studies in human immunology, helping readers make sense of the existing and emerging scientific advances. The book grounds fundamental science in the translational realm, providing insights from world renowned researchers at the top of their game in their respective fields, in both industry and academic settings. Readers will gain an understanding of the rationale and mechanisms underlying current and emerging pharmacologic approaches for interventional immunology, the gaps therein, and new ideas for better and safer therapeutic approaches, and physicians will glean information about pharmacological limitations in altering disease progression and complications. This reference on the translational realization of the burgeoning findings in immunology provides a go-to reference for experienced professional clinicians, researchers, industry scientists, and those seeking more information on the field.

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