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  • Immunodiffusion

    • 2nd Edition
    • Alfred J. Crowle
    • English
    Cancer and Chemotherapy, Volume III: Antineoplastic Agents is a collection of articles that deals with the treatment of cancer using drugs. The collection describes the various drugs that are used, the therapeutic approaches being taken, and agents that are being developed. Part I is a general review of anti-cancer drugs as regards their action mechanisms, pharmacokinetics, pharmacology, known toxicities, and clinical utility. These drugs include alkylating agents such as mitomycin C and nitrosoureas; plant alkaloids such as maytansine; antibiotics such as anthracyclines; platinum-containing complexes; antimetabolites; and hormones. Part II examines the molecular pharmacology of some major drug classes, namely, bleomycin and anthracycline. The text also discusses the chemistry, mechanism, and any structure-activity relationships found in these drug classes. Part III discusses in detail the clinical pharmacology of some antitumor drugs, for example, cisplatin and nitrosoureas. The text includes the clinical applications, biochemistry, metabolism, and the use of mathematical models in interpreting or describing resulting data. The book is helpful for pharmacologists, molecular biologists, and scientists involved in cancer-research.

  • Multilevel Analysis of Educational Data

    • 1st Edition
    • R. Darrell Bock
    • English
    Multilevel Analysis of Educational Data focuses on the principles and procedures used in the evaluation of educational progress. The selection first offers information on some applications of multilevel models to educational data, empirical Bayes methods, and a hierarchical item-response model for educational testing. Discussions focus on the interface between levels, group-level model for content elements, an application of empirical Bayes, validity generalization, improving law school validity studies, and summarizing evidence in randomized experiments on coaching. The text then takes a look at difficulties with Bayesian inference for random effects and multilevel aspects of varying parameters in structural models. The book elaborates on models for multilevel response variables with an application to growth curves and the issues and problems emerging from the application of multilevel models in British studies of school effectiveness, including enduring questions, two-level models, estimation and prediction, and econometric random coefficient modeling. The selection is a dependable reference for educators and researchers interested in the evaluation of educational progress.

  • Speech and Language

    Advances in Basic Research and Practice
    • 1st Edition
    • Volume 10
    • Norman J. Lass
    • English
    Speech and Language: Advances in Basic Research and Practice, Volume 10 is a compendium of articles that discuss a wide range of topics on speech and language processes and pathologies. This volume contains seven papers presenting a broad range of topics on speech and language. The book provides various articles discussing topics on the articulatory and perceptual characteristics associated with apraxia of speech; prevention of communicative disorders in cleft palate infants; and the relationship between normal phonological acquisition and clinical intervention. Topics on the role of auditory timing in the diagnosis and treatment of speech and language disorders; categorical perception; and the theoretical and clinical implications of speakers' abilities to control the output of their speech mechanism are presented as well. Linguists, speech pathologists, and researchers on language development will find the book very insightful and informative.

  • The Oxygen Evolving System of Photosynthesis

    • 1st Edition
    • Yorinao Inoue + 2 more
    • English
    The Oxygen Evolving System of Photosynthesis documents the proceedings of an international symposium entitled ""Photosynthetic Water Oxidation and Photosystem II Photochemistry,"" held at The Institute of Physical and Chemical Research (RIKEN), Wako, Saitama, Japan, 15-17 March 1983. Several other papers from authorities in this field are also included. This book provides in a systematic fashion the most current thoughts and insights into the field of photosynthetic oxygen evolution. The volume contains 46 chapters organized into five parts. Part I deals with the subunit structure of photosystem II reaction center pigment proteins and the charge separation (generation of positive and negative charges, P680+ and Pheo-). Part II examines the components and their function on the donor side. Part III discusses the biochemistry of the water oxidation enzyme system, polypeptide composition, and functional reconstitution. Part IV take up the functions of chloride and bicarbonate in electron transport and the mechanism of photoactivation in latent or Tris-inactivated chloroplasts. Part V discusses the fate of reducing equivalents going through the two-electron gate mechanism, together with the biochemistry of the quinone components on the acceptor side.

  • Curves and Surfaces for Computer-Aided Geometric Design

    A Practical Guide
    • 3rd Edition
    • Gerald Farin
    • English
    A leading expert in CAGD, Gerald Farin covers the representation, manipulation, and evaluation of geometric shapes in this the Third Edition of Curves and Surfaces for Computer Aided Geometric Design. The book offers an introduction to the field that emphasizes Bernstein-Bezier methods and presents subjects in an informal, readable style, making this an ideal text for an introductory course at the advanced undergraduate or graduate level.The Third Edition includes a new chapter on Topology, offers new exercises and sections within most chapters, combines the material on Geometric Continuity into one chapter, and updates existing materials and references. Implementation techniques are addressed for practitioners by the inclusion of new C programs for many of the fundamental algorithms. The C programs are available on a disk included with the text. System Requirements:IBM PC or compatibles, DOS version 2.0 or higher.

  • Knowledge Representation

    An Approach to Artificial Intelligence
    • 1st Edition
    • T.J.M. Bench-Capon
    • English
    Although many texts exist offering an introduction to artificial intelligence (AI), this book is unique in that it places an emphasis on knowledge representation (KR) concepts. It includes small-scale implementations in PROLOG to illustrate the major KR paradigms and their developments.****bac... cover copy:**Knowledge representation is at the heart of the artificial intelligence enterprise: anyone writing a program which seeks to work by encoding and manipulating knowledge needs to pay attention to the scheme whereby he will represent the knowledge, and to be aware of the consequences of the choices made.****The book's distinctive approach introduces the topic of AI through a study of knowledge representation issues. It assumes a basic knowledge of computing and a familiarity with the principles of elementary formal logic would be advantageous.****Kno... Representation: An Approach to Artificial Intelligence develops from an introductory consideration of AI, knowledge representation and logic, through search technique to the three central knowledge paradigms: production rules, structured objects, and predicate calculus. The final section of the book illustrates the application of these knowledge representation paradigms through the Prolog Programming language and with an examination of diverse expert systems applications. The book concludes with a look at some advanced issues in knowledge representation.****T... text provides an introduction to AI through a study of knowledge representation and each chapter contains exercises for students. Experienced computer scientists and students alike, seeking an introduction to AI and knowledge representations will find this an invaluable text.

  • Principles of Archaeological Stratigraphy

    • 2nd Edition
    • Edward C. Harris
    • English
    This book is the only text devoted entirely to archaeological stratigraphy, a subject of fundamental importance to most studies in archaeology. The first edition appeared in 1979 as a result of the invention, by the author, of the Harris Matrix--a method for analyzing and presenting the stratigraphic sequences of archaeological sites. The method is now widely used in archaeology all over the world.The opening chapters of this edition discuss the historical development of the ideas of archaeological stratigraphy. The central chapters examine the laws and basic concepts of the subject, and the last few chapters look at methods of recording stratification, constructing stratigraphic sequences, and the analysis of stratification and artifacts.The final chapter, which is followed by a glossary of stratigraphic terms, gives an outline of a modern system for recording stratification on archaeological sites. This book is written in a simple style suitable for the student or amateur. The radical ideas set out should also give the professional archaeologist food for thought.

  • Psychoneuroimmunology

    • 1st Edition
    • Robert Ader
    • English
    Psychoneuroimmunolog... Second Edition presents reports on the relationship between the nervous and immune systems. The book is divided into four sections. The first section details the role of neural structures and neurotransmitter signals in communication with the immune system. It documents the extensive neural connections with organs of the immune system; the dynamics of noradrenergic sympathetic innervation of spleen and thymus; and the evidence for immune signaling of the CNS. Part II elaborates the role of hormones in the modulation of immune functions; the basis for bidirectional communication between the neuroendocrine and immune systems; and the potential physiological implications of these neuroendocrine-immun... system interactions. The third part addresses behavioral influences on immune response; the effects of conditioning, stress and social interactions in modulating immune responses; and the behavioral consequences of experimentally altered or genetically determined immunologic states. The final section presents the effects of psychosocial factors on immune responses and the potential impact of behavioral interventions in modulating immunity in healthy human subjects and in patients with AIDS. Neuroscientists, endocrinologists, and immunologists will find the book interesting.

  • Planning and Design of Information Systems

    • 1st Edition
    • André Blokdijk
    • English
    Planning and Design of Information Systems provides a theoretical base and a practical method of executing the planning of computerized information systems, and the planning and design of individual applications. The book is organized into five parts, covering the non-technical and nonimplementational part of information systems planning, design, and development. Part I gives the theoretical base for the subsequent parts of the book. It discusses modeling, techniques, notations, boundaries, quality issues and aspects, and decomposition techniques and problems. Part II discusses the needs, problems, and possible solutions for user participation. It describes user organizations, in respect of culture; maturity in the use of automation and computers; and gives a synthesis of participation, cultures, maturity, and information systems development techniques. Part III describes how to develop an Information Systems Architecture, an Information Systems Plan, and a Data Architecture. Part IV presents a structured, programmed approach to planning an application in a short period while maintaining high quality, and discusses project management of application development. Part V covers information analysis, data specification and conceptual data base design, and process and dialog design.

  • Maya Subsistence

    Studies in Memory of Dennis E. Puleston
    • 1st Edition
    • Kent V. Flannery
    • English
    Maya Subsistence: Studies in Memory of Dennis E. Puleston presents studies on the history and development of Maya subsistence in honor of Maya archaeologist Dennis E. Puleston (1940-1978). The discussions are organized around four themes: ecological models for early Maya adaptations; archaeological investigations of Pre-classic and classic Maya subsistence; contributions of geography and soil science to an understanding of ancient Maya subsistence; and Maya subsistence in the post-classic, colonial, and modern eras. Comprised of 15 chapters, this book begins with an analysis of Puleston's career and a review of the history of inquiry into Maya subsistence. Maya subsistence from the earliest Pre-classic period up to the present day is then examined, with emphasis on agriculture, hunting, wild plant collecting, animal husbandry, and trade. In particular, cultural development in the Valley of Guatemala from 1500 B.C. to the Spanish Conquest is discussed, along with the resources of the tropical lowlands and actual prehistoric cornfields miraculously preserved by volcanic ashfall in El Salvador. The book also presents evidence for Maya soil and water conservation over the entire area from Yucatan to Chiapas and central Guatemala, and looks at the traditional role of women and animals in lowland Maya economy. This monograph will be of interest to archaeologists and anthropologists.

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