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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Physiological Imaging of the Brain with PET

    • 1st Edition
    • Albert Gjedde + 3 more
    • English
    Physiological Imaging of the Brain with PET provides the latest techniques and applications for PET as a tool to study the physiology of the brain, and is sponsored by the International Society of Cerebral Blood Flow and Metabolism. It covers all of the fundamental disciplines of PET in one volume. Written by international experts in brain imaging, it is a useful reference for the active brain PET scientist, and a valuable introduction to students, clinicians, and researchers who wish to take advantage of the capabilities of this technique to study the normal and diseased brain.

  • MRI Atlas of the Human Cerebellum

    • 1st Edition
    • Jeremy D. Schmahmann + 4 more
    • English
    The MRI Atlas of the Human Cerebellum constitutes the most complete, detailed work on the human cerebellum to date. This definitive work provides images in the three cardinal planes (sagittal, transverse, and coronal) at closely spaced intervals of 2 millimeters. The images are derived from MRI scans of one individual and from postmortem sections of another. It is the only such atlas set within the universally accepted framework of the Talairach stereotaxic system, derived from standard landmarks in the brain. The book includes a new nomenclature system (labeling system) which is easier to use, aids in understanding the organization of the cerebellum, and is consistent with earlier work on the anatomy of the cerebellum in animals and the development of the human cerebellum in infants.Recent studies have shown that the cerebellum is involved in much more than motor coordination alone: also in higher functions including memory, language, emotion, and attention, as well as sensory discrimination. This atlas facilitates this new era of study of the cerebellum, allowing investigators to identify cerebellar structures with precision. Everyone concerned with the anatomy, function, or dysfunction of the cerebellum should have a copy.

  • Neurobiology of Addiction

    • 1st Edition
    • George F. Koob + 1 more
    • English
    Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts — a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature.

  • Cerebellar Modules: Molecules, Morphology, and Function

    • 1st Edition
    • Volume 124
    • N.M. Gerrits + 2 more
    • English
    The present volume of Progress in Brain Research contains the proceedings of a Symposium entitled Cerebellar Modules: Molecules, Morphology and Function, which was held to mark the retirement of Jan Voogd as chairman of the Department of Anatomy at the Erasmus University of Rotterdam. The contributions of leading cerebellar scientists representing a variety of disciplines focussed around the issue of the cerebellar modular compartmentalization... the intriguing composition of which has for many decades been the driving force behind Voogd's extraordinarily detailed anatomical analyses.The first section of the book, Development, concentrates on the genetic basis of different aspects of compartmentalized development including a most important contribution on the postnatal development of the climbing fiber system. Gene expression is also an important element in the next section, Interneurons, which provides striking new data and hypotheses on the functional anatomy of granule cells, Golgi cells and unipolar brush cells. Particularly interesting are several contributions that offer a novel view on parallel fiber function. The section Modules and Circuits provides a number of state-of-the-art analyses using electrophysiological... and classical and transneuronal virus tracing techniques. The emphasis lies on the olivocerebellar circuits and the oculomotor system The final section, Models and Learning, offers an insight into the progress on the mechanisms and network organization of adaptation and learning, not only in classical paradigms like oculomotor and eye blink responses but also in studies linking gene expression to behavioral paradigmsThe editors are confident that the exciting data and concepts collected in this volume will strengthen the multidisciplinary approach in the field of cerebellar research.

  • Computational Neuroscience

    Trends in Research 2000
    • 1st Edition
    • J.M. Bower
    • English
    This volume includes papers originally presented at the 8th annual Computational Neuroscience meeting (CNS'99) held in July of 1999 in Pittsburgh, Pennsylvania. The CNS meetings bring together computational neuroscientists representing many different fields and backgrounds as well as experimental preparations and theoretical approaches. The papers published here range across vast levels of scale from cellular mechanisms to cognitive brain studies. The subjects of the research include many different preparations from invertebrates to humans.In all cases the work described in this volume is focused on understanding how nervous systems compute. The research described includes subjects like neural coding and neuronal dendrites and reflects a trend towards forging links between cognitive research and neurobiology. Accordingly, this volume reflects the breadth and depth of current research in computational neuroscience taking place throughout the world.

  • Functional Neuroanatomy of the Nitric Oxide System

    • 1st Edition
    • Volume 17
    • H.W.M. Steinbusch + 2 more
    • English
    This volume of the Handbook of Neuroanatomy is concerned with nitric oxide synthase. In this volume different research areas are presented together, which adds up to the first major review volume on the localization of nitric oxide synthase in the nervous system. The subjects range from developmental aspects in vertebrates to a functional neuroanatomy of the nervous system in vertebrates. This presentation gives an impressive look on the overwhelming presence of NOS in animal organism and the significance of NO - cGMP signaling. By clearly stating the limitations of our present knowledge the book is also a stimulant for further research. This book presents for the first time an overview of NOS and NO-cGMP signaling in the retina and urogenital system. In addition the effects if injuries on the expression of NOS are summarized in a number of models, which has not been done before.The frame of the book is a classical neuroanatomic description of the localization of NOS. Several authors give detailed advice to prevent pitfalls which may occur when different methods to locate NOS are used. In addition, several chapters detail the target structures for NO while describing the localization of NOS at the same time.All these points together make this volume very timely, i.e. overviewing a decade of NO research.

  • Peptide Receptors, Part I

    • 1st Edition
    • Volume 16
    • A. Bjorklund + 2 more
    • English
    During the last few years, the pace of research in the field of neuropeptide receptors has increased steadily: new neuropeptides were discovered, and the classification of receptor subtypes has been refined. It thus appeared essential to update the information. Peptide Receptors Part I summarizes current knowledge on ten distinct peptide families.This volume integrates photomontages and maps of quantitative receptor autoradiography, in situ hybridization histochemistry, and immunocytochemistry images. Application of these classical techniques and of new approaches such as transgenic and knock-out animals has revealed a distinct species and tissue specific variation in receptor subtypes expression and pharmacology in the mammalian central nervous system.The functional role of neuropeptides and their receptors in the CNS has been investigated thanks to the development of potent and selective receptor antagonists and agonists. The development of specific neuropeptide-related molecules will help to get a better understanding of receptor subtype physiology and neuronal distribution and may lead to innovative treatments in a variety of brain disorders.

  • Development of the Nervous System

    • 1st Edition
    • Dan H. Sanes + 2 more
    • English
    Development of the Nervous System presents a broad outline of neural development principles as exemplified by key experiments and observations from past and recent times. The text is organized along a development pathway from the induction of the neural primordium to the emergence of behavior. It covers all the major topics including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, synapse formation and plasticity, and neuronal survival and death. This new text reflects the complete modernization of the field achieved through the use of model organisms and the intensive application of molecular and genetic approaches. Original, artist-rendered drawings combined with clear, concise writing make Development of the Nervous System well suited to anyone approaching this complex field for the first time.

  • Receptor Chemistry Towards the Third Millennium

    • 1st Edition
    • Volume 31
    • M. Gianella + 3 more
    • English
    Receptor Chemistry Towards the Third Millennium is the result of papers presented at the 12th Camerino-Noordwijker... Symposium, held in Camerino, Italy in September 1999. Although much is known about the way ligands interact with receptors, which have now been isolated, characterized and cloned, many aspects still remain to be explored. In particular, differentiation into distinct subpopulations and the multiplicity of transduction processes offer more specific targets in the search for new drugs.This book will be of interest to medicinal chemists, pharmacologists, biochemists and neurologists and will also be a valuable source of reference for medical students and postgraduate students in related fields.

  • Hearing

    Its Physiology and Pathophysiology
    • 1st Edition
    • Aage R. Moller
    • English
    There is a new trend in the education of audiologists that emphasizes the basics of hearing--Hearing: Its Physiology and Pathophysiology addresses this trend. It covers not only the basics of hearing but also the basics of pathophysiology, which is not covered in a comprehensive way in any other text today. This book recognizes the fact that the diseased auditory system does indeed function, but in a different way than the normal system. Few books have addressed the pathophysiology of the ear and the auditory nervous system. Most books on hearing begin with a detailed description of the physics of sound, which scares many readers away because they believe they need to understand acoustics to understand how the ear functions. Hearing: Its Physiology and Pathophysiology does not assume that the readers are physicists, which would be analogous to assuming that visual physiologists would need to know quantum mechanics to understand how the visual nervous system functions.

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