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Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

  • Heart and Toxins

    • 1st Edition
    • Dr. Meenakshisundaram Sundaram Ramachandran
    • English
    The Heart and Toxins brings together global experts to provide the latest information and clinical trials that make the connection between genetic susceptibility, gene expression, and environmental factors in cardiovascular diseases. This unique reference, edited by renowned cardiologist Meenakshi Sundaram Ramachandran, solves the problem of managing multiple clinical cases of cardiovascular toxicity. It allows connections to be made between research, diagnosis, and treatment to avoid higher morbidity and mortality rates as a result of cardiovascular toxicity.

  • Handbook on the Toxicology of Metals

    • 4th Edition
    • Gunnar F. Nordberg + 2 more
    • English
    Handbook on the Toxicology of Metals, Fourth Edition bridges the gap between established knowledgebase and new advances in metal toxicology to provide one essential reference for all those involved in the field. This book provides comprehensive coverage of basic toxicological data, emphasizing toxic effects primarily in humans, but also those of animals and biological systems in vitro. The fourth edition also contains several new chapters on important topics such as nanotoxicology, metals in prosthetics and dental implants, gene-environment interaction, neurotoxicology, metals in food, renal, cardiovascular, and diabetes effects of metal exposures and more. Volume I covers “General Considerations” and Volume II is devoted to “Specific Metals.” A multidisciplinary resource with contributions from internationally-reco... experts, the fourth edition of the Handbook on the Toxicology of Metals is a prominent and indispensable reference for toxicologists, physicians, pharmacologists, engineers, and all those involved in the toxicity of metals.

  • Applied Dermatotoxicology

    Clinical Aspects
    • 1st Edition
    • Howard I. Maibach + 1 more
    • English
    Applied Dermatotoxicology: Clinical Aspects provides concise, systematic, and state-of-the-art information on the toxicological effects of substances on skin, and recent advances in dermal toxicity testing. This book specifically addresses the clinical presentations borne out of exposure to a variety of chemicals. It begins with an overview of skin biology to provide toxicologists with a basic understanding of its anatomy and physiology. Next it presents a variety of dermatotoxicological effects, as well at the toxic agents that cause them, with color photographs to illustrate these effects. Applied Dermatotoxicology: Clinical Aspects is an essential reference for toxicologists in industry, and for those medical professionals who encounter cases of dermal exposure to toxic agents.

  • Toxicological Survey of African Medicinal Plants

    • 1st Edition
    • Victor Kuete
    • English
    Toxicological Survey of African Medicinal Plants provides a detailed overview of toxicological studies relating to traditionally used medicinal plants in Africa, with special emphasis on the methodologies and tools used for data collection and interpretation. The book considers the physical parameters of these plants and their effect upon various areas of the body and human health, including chapters dedicated to genotoxicity, hepatotoxicity, nephrotoxicity, cardiotoxicity, neurotoxicity, and specific organs and systems.Following this discussion of the effects of medicinal plants is a critical review of the guidelines and methods in use for toxicological research as well as the state of toxicology studies in Africa. With up-to-date research provided by a team of experts, Toxicological Survey of African Medicinal Plants is an invaluable resource for researchers and students involved in pharmacology, toxicology, phytochemistry, medicine, pharmacognosy, and pharmaceutical biology.

  • History of Toxicology and Environmental Health

    Toxicology in Antiquity Volume I
    • 1st Edition
    • English
    Toxicology in Antiquity is the first in a series of short format works covering key accomplishments, scientists, and events in the broad field of toxicology, including environmental health and chemical safety. This first volume sets the tone for the series and starts at the very beginning, historically speaking, with a look at toxicology in ancient times. The book explains that before scientific research methods were developed, toxicology thrived as a very practical discipline. People living in ancient civilizations readily learned to distinguish safe substances from hazardous ones, how to avoid these hazardous substances, and how to use them to inflict harm on enemies. It also describes scholars who compiled compendia of toxic agents.

  • Introduction to Biostatistics

    A Guide to Design, Analysis and Discovery.
    • 1st Edition
    • Ronald N. Forthofer + 1 more
    • English
    The Biostatistics course is often found in the schools of public Health, medical schools, and, occasionally, in statistics and biology departments. The population of students in these courses is a diverse one, with varying preparedness. The book assumes the reader has at least two years of high school algebra, but no previous exposure to statistics is required.Written for individuals who might be fearful of mathematics, this book minimizes the technical difficulties and emphasizes the importance of statistics in scientific investigation. An understanding of underlying design and analysis is stressed. The limitations of the research, design and analytical techniques are discussed, allowing the reader to accurately interpret results. Real data, both processed and raw, are used extensively in examples and exercises. Statistical computing packages - MINITAB, SAS and Stata - are integrated. The use of the computer and software allows a sharper focus on the concepts, letting the computer do the necessary number-crunching.

  • Alcohol and Aldehyde Metabolizing Systems

    Intermediary Metabolism and Neurochemistry
    • 1st Edition
    • Ronald G. Thurman + 2 more
    • English
    Alcohol and Aldehyde Metabolizing Systems, Volume III: Intermediary Metabolism and Neurochemistry contains some of the papers presented at the Second International Symposium on Alcohol and Aldehyde Metabolizing Systems, held at the University of Pennsylvania in October 1976. Experts in the field from a wide variety of backgrounds tackled the problems of alcohol and aldehyde metabolism, discussed research findings, and examined controversial issues such as the effects of alcohol and aldehydes on intermediary metabolism. Comprised of 64 chapters, this volume begins with an analysis of the non-equilibrium behavior of biochemical systems, followed by a discussion on the configurational specificity of glycolytic enzymes. The reader is methodically introduced to redox compartmentation and the measurement of intracellular compartmentation of metabolites in rat liver; effect of chronic alcohol and oxygen tension on the development of hepatic necrosis in rats; and actions of ethanol metabolism on fatty acid synthesis in the liver. Subsequent chapters focus on regional metabolic rate in the central nervous system as related to function; effects of tetrahydroisoquinoli... derivatives of catecholamines and aldehydes on tyrosine hydroxylase; and lowering of blood acetaldehyde levels as a therapeutic approach to alcoholism. This book will be of value to practitioners and researchers from a variety of disciplines, including neurochemistry, biochemistry, physiology, cell biology, and pharmacology.

  • Encyclopedia of Toxicology

    • 3rd Edition
    • Philip Wexler
    • English
    The third edition of the Encyclopedia of Toxicology, Four Volume Set presents entries devoted to key concepts and specific chemicals, and is updated to reflect current advances in the field. It contains new information on nanotoxicology, epigenetics, persistent organic pollutants, computational toxicology and bioinformatics, controversial chemicals, and much more. Along with the traditional scientific entries, new articles focus on worldwide initiatives, the potential health and environmental effects of new technologies, and the societal implications of global legal and regulatory issues. With thoroughly updated articles, references, and resources for recommended reading, the third edition has been expanded in length, breadth, and depth, and continues to provide an extensive overview of the many facets of toxicology.

  • Toxicological Aspects of Drug-Facilitated Crimes

    • 1st Edition
    • Pascal Kintz
    • English
    Toxicological Aspects of Drug-Facilitated Crimes provides readers with an overview of the field of DFC: its history, toxicological effects, analysis, interpretation of results, the roles that age, gender and race may play, and clinical presentations of these drugs. The most commonly used drugs in DFC are addressed (alcohol, cannabis, MDMA, and cocaine), as well as an emerging range of pharmaceuticals (benzodiazepines, hypnotics, sedatives, neuroleptics, histamine H1-antagonists, or anesthetics), which are becoming more widely used, but are more difficult to detect. Edited by a world-renowned expert in the field of Forensic and Analytical Toxicology, Pascal Kintz, this book investigates toxicants of emerging concern and brings together a number of experts in the field to address the most recent discoveries on DFC toxicology.

  • Therapeutic Risk Management of Medicines

    • 1st Edition
    • Stephen J. Mayall + 1 more
    • English
    Therapeutic risk management of medicines is an authoritative and practical guide on developing, implementing and evaluating risk management plans for medicines globally. It explains how to assess risks and benefit-risk balance, design and roll out risk minimisation and pharmacovigilance activities, and interact effectively with key stakeholders.A more systematic approach for managing the risks of medicines arose following a number of high-profile drug safety incidents and a need for better access to effective but potentially risky treatments. Regulatory requirements have evolved rapidly over the past decade. Risk management plans (RMPs) are mandatory for new medicinal products in the EU and a Risk Evaluation and Mitigation Strategy (REMS) is needed for certain drugs in the US.This book is an easy-to-read resource that complements current regulatory guidance, by exploring key areas and practical implications in greater detail. It is structured into chapters encompassing a background to therapeutic risk management, strategies for developing RMPs, implementation of RMPs, and the continuing evolution of the risk management field.The topic is of critical importance not only to the pharmaceutical and biotechnology industries, but also regulators and healthcare policymakers.Some chapters feature contributions from selected industry experts.

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