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Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

  • Essays in Toxicology

    Volume 2
    • 1st Edition
    • Frank R. Blood
    • English
    Essays in Toxicology, Volume 2 covers essays on toxicology and related topics. The book presents essays on fungal toxins, such as mycotoxin, aflatoxin, moldy corn toxicoses, alimentary toxic aleukia, ochratoxin, sporidesmin, zearalenone and other estrogenic compounds, pink rot dermatitis, and slaframine. The text also includes essays on hyperbilirubinemia and cholestasis induced by alpha-naphthylisothi... taurolithocholic acid, and 2-ethyl-2-phenyl butyramide, as different forms of liver injury produced in animals. The evolution of pesticide analyses is also encompassed. Biochemists, physiologists, pathologists, and microbiologists will find the book invaluable.

  • A Textbook of Medical Jurisprudence and Toxicology

    • 6th Edition
    • Rai Bahadur Jaising P. Modi
    • English
    A Textbook of Medical Jurisprudence and Toxicology, Sixth Edition discusses medico-legal points concerning the different causes of death, examination of evidence, and crimes that merit medical attention and advice. The author reviews the legal procedures in criminal courts of medical jurisprudence, including the inquest procedures, the difficulties encountered in detecting crime, medical evidence, rules for presenting evidence, and the powers of criminal courts. The post-mortem examination concerns the external and internal examination of the deceased to establish identity (if unknown), to determine time and cause of death. Under the written orders of the court, an exhumation can take place when suspicions of foul play arises after death. The author discusses death in terms of somatic (physical) or molecular (tissues and cells dying individually after vital organs have stopped functioning). The book also describes in detail the primary modes of dying, namely, syncope, asphyxia, and coma. The book explains the medico-legal aspects of injuries, pregnancy, legitimacy, rape, miscarriage, infanticide, and insanity. This book is intended for medical students, but can also benefit students in law courses, and practitioners of legal jurisprudence and of the medical sciences.

  • Recent Advances in the Pharmacology of Toxins

    Proceedings of the First International Pharmacological Meeting Stockholm, 22-25 August, 1961
    • 1st Edition
    • H. W. Raudonat
    • English
    Recent Advances in the Pharmacology of Toxins brings together the proceedings of the Second International Pharmacological Meeting of the International Union of Physiological Sciences, held in Prague, Czechoslovakia, on August 20-23, 1963. The meeting provided a forum for discussing advances in the understanding of the pharmacology of toxins and addressed topics ranging from antagonists of bradykinin to the mode of the spread of tetanus toxin in experimental animals. This volume is comprised of 28 chapters and begins with an analysis of the effects of toxins from microorganisms on mammalian cellular metabolism and structure, followed by a review of SRS-A, a slow-reacting substance of anaphylaxis, as a potential factor in the symptoms produced by venoms and toxins. Subsequent chapters explore the release of pharmacologically active lipids by enzymes contained in toxins; the structure and function of some enzymes in snake venoms, with reference to disulfide linkages; biochemistry and pharmacology of small-molecular compounds of cobra venom; and the role of ganglioside in the mode of action of tetanus toxin. This book will be of particular value to pharmacologists and physiologists.

  • Heredity and Environment in the Functional Psychoses

    An Epidemiological–Clinical Twin Study
    • 1st Edition
    • Einar Kringlen
    • English
    Heredity and Environment in the Functional Psychoses involves an epidemiological clinical study of twins carried out at the University Psychiatric Institute in Oslo. The author reviews the history and nosological aspects of psychiatry. In his study of twin genetics, the author seeks to answer the questions "What is inherited?" and "How is it inherited?" In his review of 342 pairs of twins in the Central Register of Psychosis, his study had the following aims: to obtain true concordance figures for all types of functional psychoses; to study problems pertaining to nosology; and to study a larger sample of discordant pairs in order to clarify crucial environmental factors. His findings show that concordance figures for schizophrenia are 25-38 per cent in monozygotic twins and 4-10 per cent ion dizygotic twins. He points out that the difference in such concordance rates between the two types of twins is statistically significant. The data supports the (weak) assumption of a genetic factor in the etiology of schizophrenia. Behavioral scientists, psychiatrists, child psychologists, and researchers involved in genetics will find this book helpful and informative.

  • Clinical Pharmacology

    Proceedings of the 7th International Congress of Pharmacology, Paris 1978
    • 1st Edition
    • P. Duchêne-Marullaz + 2 more
    • English
    Clinical Pharmacology provides a detailed discussion on toxicology. This discussion includes the chemotherapy of parasitic diseases. Some parts of the book focus on topics on immunopharmacology. Such topic as the genetic and environmental factors that contribute to individual’s varying response to drugs is explained. The book covers such topics as the methods and models for the isoniazid acetylation polymorphism. The issues that arise in the administration of drugs in the neonatal period are assessed. Another topic of interest is the effects of diseases on the absorption of drugs. The pharmacokinetic and pharmacodynamic characteristics of a drug are evaluated. The pharmacogenetic investigation amobarbital disposition is presented completely. The book then presents the use and consumption of drugs in different locations and some clinical considerations. The procedures and methods of analysis for such drug are also reviewed . The book can serve as a valuable tool for pharmacists, medical doctors, pediatricians, students, and researchers in the field of medicine.

  • Criteria (Dose/Effect Relationships) for Organochlorine Pesticides

    Report of a Working Group of Experts Prepared for the Commission of the European Communities, Directorate-General for Employment and Social Affairs, Health and Safety Directorate
    • 1st Edition
    • M. Mercier
    • English
    Criteria (Dose/Effect Relationships) for Organochlorine Pesticides presents the effect of organochlorine compounds on the immunological processes. This book deals with several organochlorine pesticides. Organized into 15 chapters, this book begins with an overview of the properties and toxicology of dichlorodiphenyl trichloroethane (DDT), a potent non-systemic stomach and contact insecticide of high persistence on solid surface. This text then examines the absorption, metabolism, and excretion of lindane in laboratory animals and in humans as well. Other chapters consider the studies on the carcinogenic potential as well as the mutagenic effects of dieldrin. This book discusses as well the metabolism and pharmacokinetics of endrin, which is a non-systemic and persistent insecticide used primarily on field crops. The final chapter deals with the need for further evaluation of any possible long-term risks to humans from the production and use of the technical product. This book is a valuable resource for agriculturists and research workers.

  • Essays in Toxicology

    Volume 1
    • 1st Edition
    • Frank R. Blood
    • English
    Essays in Toxicology, Volume 1 covers essays in toxicology and related topics. The book presents essays on the use of poisons as tools in studying the nervous system as well as teratology. The text also includes essays on the significance of methemoglobinemia in toxicology and lead poisoning. Biochemists, plant and animal physiologists, pharmacologists, pathologists, microbiologists, entomologists, food technologist, and people involved in forensic medicine and industrial medicine.

  • Clinical Ocular Pharmacology

    • 2nd Edition
    • Jimmy D. Bartlett
    • English
    Clinical Ocular Pharmacology, Second Edition covers the diagnostic and therapeutic clinical procedures in the administration of drugs to the eye. This book is organized into five parts encompassing 35 chapters that evaluate the basic pharmacologic principles that govern the different types of ophthalmic drugs. It addresses the pharmacologic agents useful in the diagnosis and treatment of ocular diseases. Some of the topics covered in the book are the basic science of ocular pharmacology; clinical administration of ocular drugs; drugs affecting the autonomic nervous system; types of local anesthetics; review of anti-inflammatory drugs; and examination of inhibitors of aqueous formation. Other parts deal with the development of contact lens solution in clinical practice and the pharmacologic management of strabismus. These topics are followed by discussions of the legal basis of using drugs in optometry and the systemic effects of ocular drugs. The concluding part is devoted to the diseases of the optic nerve. The book can provide useful information to doctors, optometrists, pediatricians, students, and researchers.

  • Epidemiology

    Proceedings of the 12th International Cancer Congress, Buenos Aires, 1978
    • 1st Edition
    • Jillian M. Birch
    • English
    Advances in Medical Oncology, Research and Education, Volume III: Epidemiology covers the proceedings of the 12th International Cancer Congress. The title presents papers that deal with the epidemiological aspect of oncology. The first part of the text covers cancer epidemiology, and then proceeds to tackling occupational cancer. Next the selection talks about seroepidemiology and human cancer. The text also details the interaction between genetic and environmental factors in human cancer. The book will be of great use to students, researchers, and practitioners of oncology.

  • Drug Design

    Medicinal Chemistry: A Series of Monographs, Vol. 8
    • 1st Edition
    • E. J. Ariëns
    • English
    Drug Design, Volume VIII covers a critical review and new extensions of quantitative methods in drug design, the design of particular types of agents, such as synthetic sweeteners, and selective ion binding compounds. The book discusses the advances in the methodology of quantitative drug design; the application of pattern recognition to drug design; and the design of controlled drug delivery systems. The text also describes the use of receptor binding as a tool in the development of new bioactive steroids; the design of synthetic sweeteners; and the prospective assessment of environmental effects of chemicals. The design of selective ion binding macrocyclic compounds and their biological applications are also encompassed. Chemists, pharmacologists, biochemists, and people involved in drug design and manufacture will find the book invaluable.

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