Skip to main content
Elsevier
View Cart

Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

  • Drug Design

    Medicinal Chemistry: A Series of Monographs, Vol. 10
    • 1st Edition
    • E. J. Ariëns
    • English
    Drug Design, Volume X covers promising and current developments in drug design. The book discusses procedures as applied in the practice of drug design; the structural aspects of the structure-activity relationships of neuroleptics; and promising perspectives in the highly actual field of bioactive peptides. The text also describes the application of the dynamic systems analysis to the antihypertensive drug action; polymeric drug delivery systems; and the design of biocompatible polymers. The structure-activity relationships of insect repellents as a basis for the design of such agents, as well as the approaches to the multivariate data analysis in structure-activity relationships, which is an essential aspect of drug design, are also encompassed. Chemists, pharmacologists, bioengineers, and people involved in drug design and manufacture will find the book invaluable.

  • Drug Design

    Medicinal Chemistry: A Series of Monographs, Vol. 7
    • 1st Edition
    • E. J. Ariëns
    • English
    Drug Design, Volume VII covers the design of agents such as blood substitutes, pesticides derived from insect pheromones, and herbicides related to the auxin-type plant hormones. The book discusses the design of artificial blood substitutes and auxin-type herbicides; the use of insect pheromones as a basis for the development of more effective selective pest control agents; and the development and application of new steric substituent parameters in drug design. The text also describes the use of computer technology in drug design. Pharmacologists, chemists, biochemists, and people involved in drug design and manufacture will find the book invaluable.

  • Toxicology of Chemical Mixtures

    Case Studies, Mechanisms, and Novel Approaches
    • 1st Edition
    • Raymond S.H. Yang
    • English
    Although toxicologic studies in the laboratory often focus on a single chemical, in the larger world, mixtures of chemicals are routinely encountered. Toxicology of Chemical Mixtures examines the mechanisms of interactions and health effects stemming from chemical mixtures in the environment. Toxicologists, pharmacologists, environmental scientists, and professionals involved in environmental clean-ups will benefit from its content.Emphasis is on low-level, long-term exposure.

  • Drug Design

    Medicinal Chemistry: A Series of Monographs, Vol. 3
    • 1st Edition
    • E. J. Ariëns
    • English
    Drug Design, Volume III covers the mode of action of biologically active compounds. The book discusses microbial transformations that have been used in the preparation of drugs or closely related substances; the use of linear free energy parameters and other experimental constants in structure-activity studies; and the mode of action of anticoagulants structurally and functionally related to vitamin K. The text also describes the design of beta-blocking drugs, biologically active acridines, local anesthetics, and insect chemosterilants. The molecular approach for designing inhibitors to enzymes involved in blood clotting is also considered. Chemists, pharmacologists, and people involved in drug design.

  • Handbook of Toxicologic Pathology

    • 1st Edition
    • Wanda M Haschek + 1 more
    • English
    This is the first comprehensive reference work on toxicologic pathology, an emerging field that integrates the mechanisms of toxic injury with the resulting pathology. Chapters deal systematically with organ-specific toxic injury, describing the mechanisms of injury, morphological expression of the injury, and evaluation of the pathology. Additional chapters introduce the field to the uninitiated and address such topics as techniques used for morphological evaluation, risk assessment, and regulatory aspects. The Handbook of Toxicologic Pathology will quickly establish itself as the classic reference work in this field for years to come.

  • Evaluating Alcohol and Drug Abuse Treatment Effectiveness

    Recent Advances
    • 1st Edition
    • Linda Carter Sobell + 2 more
    • English
    Evaluating Alcohol and Drug Abuse Treatment Effectiveness: Recent Advances is a collection of papers that covers the advancement in rehabilitation of individuals with a history of substance abuse. The title aims to find ways in identifying the treatment that best fits a specific patient. The text first provides a historical account of alcohol and drug treatment outcome research. Next, the selection considers the use of multiple measures of life health to assess alcohol treatment. Chapter 3 deals with the behavioral assessment and treatment evaluation of narcotic addiction, while Chapter 4 talks about the evaluation of behavioral and traditional treatment of alcoholics. The fifth chapter tackles the contingency contracting with drug abusers, and the sixth chapter covers the development of a prototype for the evaluation of alcohol treatment. The text also details the problems in alcohol treatment along with the improvement of confidence in treatment of substance abuse. The book will be of great use to behavioral scientists, social workers, and mental health specialists.

  • Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells

    • 1st Edition
    • T.E. Gram
    • English
    Research has shown that the lung is capable of metabolically activating xenobiotics into intermediates that can covalently bind to pulmonary tissue. Further, it has been shown that the lung consists of many distinct cell types with the ability to take up and sequester metabolically unchanged drugs and chemicals that are ultimately toxic in effect. This volume reflects the extent of these developments and provides a state-of-the art reference in a rapidly evolving field incorporating both drug metabolism and pulmonary toxicology research.

  • Basic Pharmacology

    • 2nd Edition
    • R W Foster
    • English
    Basic Pharmacology, Second Edition, similar to the first edition, talks about the relationship between the human body and therapeutic drugs. A large part of this book discusses the nervous system and the way certain drugs operate and affect it. The first part of this book covers the importance of having a firm understanding of the organ system, especially the nervous system. Understanding the systems is the initial step in learning how a drug affects the body, both internally and externally. This book also clarifies that a drug's impact occurs when it comes in contact with a chemical component of the body (enzymes, hormones, membranes, etc.). The next sections of this book discuss miscellaneous topics of the human anatomy, such as the brain, eyes, lungs, and various muscles. This edition also explains how a drug acts on each of those body parts. This book serves as a great reference to students affiliated in the anatomy, biology, pharmacy, and related fields.

  • Bacterial Endotoxins

    A Comprehensive Treatise
    • 1st Edition
    • George Weinbaum + 2 more
    • English
    Microbial Toxins, Volume IV: Bacterial Endotoxins covers a general introduction of bacterial endotoxins, as well as research concerning structure (both morphological and physical), chemistry, immunology, biosynthesis, and genetics of bacterial endotoxins. The book describes the general characteristics of bacterial endotoxins; the anatomy and chemistry of Gram-negative cell envelopes; and the physical structure of bacterial lipopolysaccharides. The text also discusses the isolation and chemical and immunological characterization of bacterial lipopolysaccharides; the chemistry of the unique carbohydrates of bacterial lipopolysaccharides; and the relation of bacteriophage attachment to lipopolysaccharide structure. The chemical and biological heterogeneity of endotoxins, as well as the biosynthesis of the core region of lipopolysaccharide are also considered. The book further tackles the biosynthesis of O-antigens and the genetic aspects of biosynthesis and structure of Salmonella lipopolysaccharide. Microbiologists, biochemists, bacteriologists, immunologists, and people involved in biochemical research will find the book useful.

  • Nitrogen and Phosphorus Solvents

    • 2nd Edition
    • Volume 2
    • D.R. Buhler + 1 more
    • English
    This particular volume, Nitrogen and Phosphorus Solvents, is the second in a comprehensive and up-to-date series. The introduction of new nitrogen- and phosphorus- containing solvents used in industry has been accompanied by an explosion of knowledge about their properties, toxicity and metabolism. Even a relatively simple compound such as N-methylformamide undergoes a complex metabolic transformation in mammals. Such information, and other considerations contained in this volume will supply researchers and students with an excellent information source on modern mechanistic toxicology, while helping to provide a sound scientific basis for accurate health risk assessment.

Related subjects