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Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

  • Toxicology: What Everyone Should Know

    • 1st Edition
    • Aalt Bast + 1 more
    • English
    Toxicology: What Everyone Should Know is an essential reference for anyone looking for an entry into this fascinating field of study. This innovative book describes important discoveries in toxicology through the ages, explores their historical and sociological impacts, and shows how they still influence recent, state-of-the-art developments. In addition, the book shows how these developments are extrapolated into public and political perceptions on risks and the regulatory consequences, emphasizing environmental issues, such as manmade and natural chemicals, their interaction and impact, nutrition, and drugs. Users will find a cutting-edge approach to nutritional and combinatorial toxicology, risk evaluation modeling and the benefits of chemicals exposure (nutrition versus man-made chemicals), environmental health, and legislative frameworks to control the public’s chemical exposure. This is an essential reference for those looking for an introduction to toxicology, its past, and exciting future.

  • A Text-Book of Medical Jurisprudence and Toxicology

    • 1st Edition
    • Rai Bahadur Jaising P. Modi
    • English
    Medical Jurisprudence and Toxicology for India covers some essential details and practical aspects of medical jurisprudence and toxicology. This book is organized into two part encompassing 34 chapters. The opening chapters of Part I deal with legal procedure in criminal courts, physical evidence of the crime, autopsy, exhumation, and some medico-legal practices. Considerable chapters are devoted to other aspects of legal medicine, including determination of death causation, legitimacy of evidence, incident of rape and unnatural offenses, miscarriage, infanticide, insanity, and the privileges of medical men. Part II focuses on the toxicological aspects. This part emphasizes the medico-legal aspects of some classes of poisons, such as corrosive, irritant, neurotic, cerebral, spinal, cardiac, and peripheral poisons. This book will prove useful to medical college students.

  • Physico-Chemical Aspects of Drug Action

    Proceedings of the Third International Pharmacological Meeting
    • 1st Edition
    • E. J. Ariëns
    • English
    Physico-Chemical Aspects of Drug Action, Volume 7 covers topics on drug kinetics and the overall physicochemical properties of the drug in relation therewith, and the physicochemical aspects of the drug-receptor interaction, putting emphasis on receptor mechanisms and specific properties required for certain types of drugs in this respect. The book starts with some contributions dealing with various general aspects of drug kinetics followed by some contributions dealing with the relationship between certain physicochemical properties of drug molecules and their action. The text describes the pharmacokinetics and dose-concentration relationships; the time course of the biological response to drugs; and the empirical equations for correlating biological efficiency of organic compounds. The text also describes molecular basis for the action of chemotherapeutic drugs; the structure-activity studies on sulphonamides; and the water extrusion hypothesis. The mathematical treatment of two-point attachment between drug and receptor; the molecular properties and biological activity of catecholamines and certain related compounds; and the structure-activity relationships of diarylcarbinolethers are also considered. The book further tackles quantum mechanically-derived electronic distributions in the conformers of 2-pam; and the molecular basis for the action of certain drugs in the central nervous system. Pharmacologists and chemists will find the book invaluable.

  • Electronic Waste

    Toxicology and Public Health Issues
    • 1st Edition
    • Bruce A. Fowler
    • English
    Electronic Waste: Toxicology and Public Health Issues discusses the major public health concerns due to the presence of toxic chemicals that are generated from improper recycling and disposal practices of electronic waste (e-waste). This book highlights hazardous inorganic chemicals found in e-waste, including arsenic, cadmium, lead, mercury, gallium, iridium, and nanomaterials, also focusing on health issues related to the presence of BPA, styrene, and other plastic components and combustion products, while also identifying populations at special risk. To provide readers with potential solutions to this global problem, Dr. Fowler presents risk assessment approaches using chemicals, mixtures, biomarkers, susceptibility factors, and computational toxicology. He discusses how to translate the information gathered through risk assessment into safe and effective international policies. The final chapter is devoted to future research directions. This is a timely and useful resource for all those concerned with the health issues surrounding e-waste management and proper disposal, including toxicologists, public health and policy officials, environmental scientists, and risk assessors.

  • Mycotoxins in Foodstuffs — 3

    Invited Lectures Presented at the Third International IUPAC Symposium on Mycotoxins in Foodstuffs, Paris, France, 16 - 18 September, 1976
    • 1st Edition
    • M. Jemmali
    • English
    Mycotoxins in Foodstuffs—3 is a collection of invited lectures presented at the International Union of Pure and Applied Chemistry's Third International Symposium on Mycotoxins in Foodstuffs, held in Paris, France, on September 16-18, 1976. The papers explore the health hazards posed by mycotoxins found in foodstuffs, including aflatoxins and trichothecenes, as well as ways of addressing the problem. This book is comprised of 11 chapters and begins with a discussion on how to design a program for monitoring problem foods and surveying potential problem foods for a number of mycotoxins. The next chapter describes a methodology for the design and evaluation of testing programs to estimate aflatoxin concentrations in granular foodstuffs. The action taken by various countries regarding mycotoxins in foodstuffs (food and feed), under legislative provision or code of practice, is then examined. Subsequent chapters deal with the metabolism of aflatoxin and other mycotoxins in relation to their toxicity and the accumulation of residues in animal tissues; mode of action of trichothecenes; and mode of action and human health aspects of aflatoxin carcinogenesis. The human health hazards associated with mycotoxins are also considered, along with prevention, elimination, and detoxification of aflatoxins. This monograph will be a useful resource for chemists, nutritionists, food scientists, and toxicologists.

  • Reproductive and Developmental Toxicology

    • 2nd Edition
    • Ramesh C. Gupta
    • English
    Reproductive and Developmental Toxicology, Second Edition, is a comprehensive and authoritative resource that provides the latest literature on this complex subject with a primary focus on three core components—parent, placenta, and fetus—and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics, including nanoparticles and radiation, gases and solvents, smoking, alcohol and drug abuse, and metals, amongst others. With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages, also including discussions on reproductive and developmental toxicity in domestic animals, fish, and wildlife. Completely revised and updated to include the most recent developments in the field, the book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists, and teratologists from academia, industry, and regulatory agencies.

  • Toxicology in the Middle Ages and Renaissance

    • 1st Edition
    • Philip Wexler
    • English
    Toxicology in the Middle Ages and Renaissance provides an authoritative and fascinating exploration into the use of toxins and poisons in the Middle Ages and Renaissance. Part of the History of Toxicology and Environmental Health series, this volume is a follow-up, chronologically, to the first two volumes which explored toxicology in antiquity. The book approximately covers the 1100s through the 1600s, delving into different aspects of toxicology, such as the contributions of scientific scholars of the time, sensational poisoners and poisoning cases, as well as myths. Historical figures, such as the Borgias and Catherine de Medici are discussed. Toxicologists, students, medical researchers, and those interested in the history of science will find insightful and relevant material in this volume.

  • Adverse Effects of Engineered Nanomaterials

    Exposure, Toxicology, and Impact on Human Health
    • 2nd Edition
    • Bengt Fadeel + 2 more
    • English
    Adverse Effects of Engineered Nanomaterials: Exposure, Toxicology, and Impact on Human Health, Second Edition, provides a systematic evaluation of representative engineered nanomaterials (ENM) of high volume production and their high economic importance. Each class of nanomaterials discussed includes information on what scientists, industry, regulatory agencies, and the general public need to know about nanosafety. Written by leading international experts in nanotoxicology and nanomedicine, this book gives a comprehensive view of the health impact of ENM, focusing on their potential adverse effects in exposed workers, consumers, and patients. All chapters have been updated with new sections on the endocrine system and other organ systems. In addition, other newly added sections include introductory chapters on the physio-chemical characterization of nanomaterials and interactions between nanomaterials and biological systems, as well as a new chapter that explores risk assessment and management of nanomaterials. This book fills an important need in terms of bridging the gap between experimental findings and human exposure to ENM, also detailing the clinical and pathological consequences of such exposure in the human population.

  • New Pesticides and Soil Sensors

    • 1st Edition
    • Alexandru Mihai Grumezescu
    • English
    New Pesticides and Soil Sensors, a volume in the Nanotechnology in the Agri-Food Industry series, is a practical resource that demonstrates how nanotechnology is a highly attractive tool that offers new options for the formulation of ‘nanopesticides’. Recent advances in nanopesticide research is reviewed and divided into several themes, including improvement of the water solubility of poorly soluble pesticide active ingredients to improve bioavailability and the encapsulation of pesticide active ingredients within permeable nanoparticles with the aim of releasing pesticide active ingredients in a controlled or targeted manner, while also protecting active ingredients from premature photo-degradation.

  • Pharmacology of Cholinergic and Adrenergic Transmission

    Proceedings of the Second International Pharmacological Meeting, August 20—23, 1963
    • 1st Edition
    • G. B. Koelle + 2 more
    • English
    Section on Pharmacology of the International Union of Physiological Sciences (SEPHAR), Proceedings of the Second International Pharmacological Meeting, August 20-23, 1963, Volume 3: Pharmacology of Cholinergic and Adrenergic Transmission focuses on the effects of drugs on muscles, nerve fibers, and the central nervous system. The selection first offers information on the role of sodium ions in the release of acetylcholine and the distribution and release of acetylcholine in muscles. Discussions focus on the effects of sodium deficiency on ACh release in perfused ganglia; effects of sodium pump inhibitors on ganglionic and myoneural transmission; distribution of ACh and choline acetylase in muscle; and ACh release after denervation. The text then ponders on the roles of acetylcholine and acetylcholinesterase in junctional transmission and correlated studies of monoamines and acetylcholinesterase in sympathetic ganglia, manifesting the distribution of adrenergic and cholinergic neurons. The publication examines the action of acetylcholine and related drugs on mammalian nonmyelinated nerve fibers; possible mechanisms of acetylcholine action in muscles; and electrophysiological analysis of cholinergic transmission in sympathetic ganglia. The text then reviews the interactions of cholinomimetic and cholinergic blocking drugs at sympathetic ganglia; evolution of cholinoreceptive sites of locomotor muscle; and pharmacological blocking of central cholinoreactive systems and the possibilities of its therapeutic application. The selection is a dependable source of data for readers interested in the pharmacology of cholinergic and adrenergic transmission.

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