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Elsevier

Books in Life sciences

  • Myasthenia Gravis, Part B

    • 1st Edition
    • Volume 183
    • English
    Myasthenia Gravis, Part B, Volume 183 in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Typical and Atypical Clinical Presentations, Diagnosis and Differential Diagnosis, Clinical Evaluation, Myasthenia Gravis in Women, Fatigue and Myasthenia Gravis, Clinical and Electrophysiologic Outcomes, Standard Treatment and Different Geographical Approaches, Rescue Treatments, Novel Treatments for Myasthenia Gravis, Measuring Treatment-Related Side Effect Burden in Myasthenia Gravis, Exercise and Myasthenia Gravis, The Social and Personal Impact of Myasthenia Gravis, and Future Perspectives.

  • Machine Learning in Drug Development: Part 1

    • 1st Edition
    • Volume 64
    • English
    Machine Learning in Drug Development: Part One, Volume 64 in the Annual Reports on Medicinal Chemistry series, highlights new advances in the field. Chapters in this release include Artificial Intelligence in Small Molecule and Nucleic Acid Research: A Review, AI-aided Drug Development for Protein Degraders: Design, Lead Identification, and Optimization, AI-aided Drug Development for Protein Degraders: Biology Validation, Disease-association, Drug Repurposing, Transforming Modern Drug Discovery with Machine Learning, Artificial Intelligence in the Development of Antiviral Drugs: Progress and Applications, Artificial Intelligence for Drug Target Identification, and Machine Learning in Proteomic Biomarker Discovery.

  • Biomarkers in Kidney Transplantation

    Clinical Aspects and Laboratory Determinations
    • 1st Edition
    • Dr Smita Pattanaik + 1 more
    • English
    Biomarkers in Kidney Transplantation: Clinical Aspects and Laboratory Determination provides a focused study on traditional and emerging biomarkers to predict early rejection of kidney transplants supporting appropriate therapeutic interventions. Coverage includes predictive and diagnostic biomarkers for different types of rejections, including biomarkers of acute, chronic/sub chronic rejection or clinical rejection, T-cell mediated rejection, antibody mediated rejection and mixed rejection. Comparisons are provided for broad classification of pharmacokinetic versus pharmacodynamic biomarkers, and differentiation is shown between the susceptibility, diagnostic, predictive, prognostic and monitoring biomarkers.Coverage of the analytical aspects of biomarker measurement, the process of biomarker discovery and their clinical validation addresses both the clinical features of biomarkers as well as the pitfalls of determining such biomarkers in clinical laboratories. By combining all current markers known for kidney transplant in one collection, this easy-to-use reference is perfect for pathologists, clinical pharmacologists, clinical laboratory scientists and all physicians involved in organ transplantation, including immunologists and transplant surgeons.

  • Interaction of Food Macromolecules

    The Matrix of Future Foods
    • 1st Edition
    • Ibrahim Khalifa + 2 more
    • English
    Interaction of Food Macromolecules: The Matrix of Future Foods provides a detailed understanding on why biological macromolecules, i.e., proteins, lipids, and carbohydrates with ligands interactions are essential to understanding biology at the molecular level. The book aims to create a multidisciplinary forum of discussion on the interaction between macromolecules and ligands, providing an understanding on how biological macromolecules with ligands interactions are central to facilitating the discovery, design, and development of future, functional foods. In addition, it outlines information available on the macromolecules-ligan... interaction that happens inside the food matrixes and inside our bodies.Knowing about the mechanisms responsible for the macromolecules-ligan... recognition and binding facilitates the discovery, design, and development of future and functional foods.

  • Bladder Cancer Breakthroughs

    A Global Perspective on Diagnosis, Treatment, and Patient Care
    • 1st Edition
    • Bhupendra G. Prajapati + 2 more
    • English
    Bladder Cancer Breakthroughs: A Global Perspective on Diagnosis, Treatment, and Patient Care is a groundbreaking scientific resource that delves into the latest advancements in the diagnosis and treatment of bladder cancer, a prevalent malignancy affecting hundreds of thousands worldwide. This meticulously curated volume brings together contributions from leading scientists and healthcare professionals from around the globe, providing a comprehensive overview of contemporary understanding and innovative strategies in managing this complex disease. Bladder Cancer Breakthroughs: A Global Perspective on Diagnosis, Treatment, and Patient Care is not merely a collection of research findings; it is a vital resource that fosters a holistic perspective on patient-centered care. By synthesizing clinical expertise and evidence-based practices, this book aims to empower healthcare providers with the knowledge and tools needed to improve outcomes for individuals living with bladder cancer, ultimately contributing to the global fight against this challenging disease. This book serves as an essential guide for healthcare providers, including physicians, oncologists, immunologists, pharmacists, and physical therapists, striving to enhance patient care and treatment outcomes

  • Harnessing Quorum Quenching for Disease Management

    • 1st Edition
    • Arpita Roy + 2 more
    • English
    Harnessing Quorum Quenching for Disease Management explores the process of quorum quenching in disrupting bacterial cell communication and how this mechanism can be utilized in the medical field. This book provides a detailed overview of quorum quenching and quorum sensing, delving into the key aspects of this process including the enzymatic mechanisms and methods available to study these. It covers quorum quenching applications, including the regulation of virulence factors, antimicrobial resistance and disease treatment, and the use of quorum quenching bacteria for medical intervention. It also considers genetically modified organisms to produce quorum quenching enzymes, nanomaterials for optimizing quorum quenching, in silico technology and the impact of synthetic biology, closing with a discussion of the current limitations and future prospects for this field. This book is an ideal reference for researchers and advanced students with an interest in quorum quenching and quorum sensing working across a range of fields, including microbiology, cell biology, biomedicine, biochemistry, biotechnology and related areas.

  • Encyclopedia of Immunobiology

    • 2nd Edition
    • Paul Kaye
    • English
    Encyclopedia of Immunobiology, Second Edition, Five Volume Set covers the full range of Immunology, presenting topics logically and making extensive use of "hot links" to refer the reader to related content. The new edition is not just an update of the original title; it vastly expands fields like immunotherapy, immunity to viral infection, vaccine development, inflammatory responses, and high throughput analyses. Containing 350 chapters written by world-leading experts, this edition integrates all concepts coherently and logically to paint a comprehensive picture of the evolving field of Immunology.The immune system, complex and multi-layered, has evolved to differentiate between "self" and foreign pathogens, providing protection against infections while dysregulation can cause diseases like autoimmunity, allergies, and inflammatory disorders. This understanding has led to numerous therapeutic interventions crucial for human health improvement.

  • Soil Microorganisms for Plant Growth Promotion and Soil Health

    • 1st Edition
    • Gustavo Santoyo
    • English
    Soil Microorganisms for Plant Growth Promotion and Soil Health provides readers with an overview of plant growth-promoting microorganisms and their molecular mechanisms to improve plant growth and soil health. Students and researchers in soil science will gain a comprehensive understanding of soil microbiota diversity and functions, along with insights into the mechanisms by which plant growth, including molecular processes involved in nutrient acquisitions and defense mechanisms work. In addition, the book provides a noteworthy emphasis on fungi.A soil beneficial microbe cannot only be the living cells, but also their components, such as molecules or enzymes produced by this beneficial microbiota. Molecules like microbial phytohormones can be excellent promoters or regulators of plant growth, as well as proteins and other compounds like volatiles, which might elicit a systemic resistance response against pathogenic threats. Therefore, plant growth promoters living in soil, associated with plant roots, could act through direct beneficial interactions with the plant, by stimulating or regulating growth responses to environmental conditions, or indirectly by inhibiting the growth of potential microbial pathogens and herbivore pests.

  • Oral Delivery of Insulin

    • 2nd Edition
    • T.A. Sonia + 1 more
    • English
    Oral delivery of Insulin, Second Edition is a complete reference on non-invasive insulin delivery systems, focusing on the prospect of oral delivery of peptides. The chapters in the revised edition present a comprehensive evaluation of the insulin therapy approaches, with an emphasis on insulin delivery strategies and current advances in engineered insulin delivery systems such as nano/microcarriers and hydrogels. Chapters provides an overview of diabetes mellitus, cover technological innovations, explore artificial intelligence and machine learning approaches to manage diabetes, explore a wide range of non-invasive and alternative routes of insulin administration, and much more.Other chapters cover challenges and strategies in oral insulin delivery, the experimental techniques used to develop oral insulin carriers, the use of polymeric nano and microparticles for insulin delivery, and the use of lipids and inorganic nanoparticles in insulin delivery. The final chapter provide an overview of current clinical trials on insulin delivery and future perspectives in the area. Clinicians can benefit from this information to develop a clear understanding about the research carried out worldwide in the field of oral delivery of insulin, including those in the clinical phase.

  • Hazardous Chemicals in Medical Devices

    Safety, Risk Analysis, and Regulations
    • 1st Edition
    • Prakash Srinivasan Timiri Shanmugam + 1 more
    • English
    Hazardous Chemicals in Medical Devices: Safety, Risk Analysis, and Regulations provides a comprehensive overview of the hazardous chemicals used in medical device manufacturing. The book discusses the basics of these chemicals, their presence in various components, and the regulations that govern their use. It also delves into the processes involved in manufacturing and the added chemicals during these stages. With a focus on risk assessment and analysis, the book emphasizes the importance of safety in medical devices and outlines the types of hazards associated with these substances.The book further explains the regulatory classification of hazardous chemicals and the labeling and safety data sheet requirements. It includes a list of notified bodies that discuss hazardous substance data, aiding in risk assessment and toxicological profiling. Additionally, it underscores the critical understanding of toxicological profiles of materials used in medical devices, ensuring that readers are well-informed about the safety measures and regulations in place to protect both manufacturers and users.

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