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Elsevier

Books in Life sciences

  • Functional Connectivity of the Human Brain

    From Mechanisms to Clinical Applications
    • 1st Edition
    • Maria A. Rocca + 1 more
    • English
    Functional Connectivity of the Human Brain: From Mechanisms to Clinical Applications is a comprehensive review of mechanisms and analysis of methods of functional connectivity to map brain organization in healthy individuals and sick patients. Providing full coverage of the discipline for a wide audience of different research and clinical specialists, this volume begins with descriptions of mechanisms of functional connectivity and methodological approaches to quantify it, followed by a focus on how functional connectivity has been used to describe brain function in healthy people and to characterize network disruption in diseased conditions. This practical balance in book structure is suitable for readers with a technical or clinical orientation, providing background that is easy to approach for clinicians or scientists. Chapters examine fMRI and electrophysiological techniques, brain maturation, aging, and cognitive neurosciences, as well as functional connectivity in neuroinflammatory, neurodegenerative, and neuropsychiatric conditions. Future perspectives look forward to functional connectivity in multimodal analysis, artificial intelligence, and more. This book will be of use to a wide audience working on functional connectivity experiments, as well as any courses on the topic.

  • Fundamentals of Brain Organoids for Neurological Diseases

    • 1st Edition
    • Balachandar Vellingiri + 1 more
    • English
    Researchers use brain organoids to study the formation of neural tissues, investigate the processes involved in brain development, and gain a better understanding of neurological disorders and diseases. Brain organoids are particularly useful in studying developmental disorders, neurodegenerative diseases, and infectious diseases that affect the brain. Fundamental of Brain Organoids for Neurological Diseases provides a practical resource for researchers on how to utilize and apply brain organoids. This book is organized into nine distinct sections, guiding the reader through each step from advanced overview of what organoids are to the use of brain organoids in various neurodevelopmental disorders and neurodegenerative diseases. In later sections, this book reviews the necessary methods involved in organoid development including the elements and challenges involved. This book will serve as a valuable tool for researchers, helping to advance the understanding of brain biology and disease mechanisms.

  • Biopharmaceutical Ecosystems

    A Comparative Study of U.S. and European Systems
    • 1st Edition
    • David R. Williams
    • English
    The ecosystem perspective on organizations and economic settings is relatively new. It expands on work that looks at bio-clusters, concentrating on the relationship between human and financial capital. The perspective takes an expansive view of biopharmaceuticals in relation to stakeholders and the social, political, and economic landscape, including other life science companies, academia, non-profits, government entities, and health systems. The biotechnology and pharmaceutical industries have been merging for some time, with biotechnology often portrayed as a disruptive innovation to the pharmaceutical industry. A fuller description of this activity put into the greater context of the ecosystem perspective is warranted.Biopharmac... Ecosystems: A Comparative Study of U.S. and European Systems puts forward a picture of biopharmaceutical ecosystems in the USA and Europe. It examines and expands current thinking on the development of the ecosystem perspective on biopharmaceuticals. The title considers multiple locations, with countries in the top 15 of biopharmaceutical exporters selected. It pays particular attention to shifts in the political and economic landscape, and how such changes affect ecosystems. The underlying aim of biopharmaceutical ecosystems is to further the development of new drugs, reduce time to market, and lower costs. In explaining ecosystems, the book applies a quadruple helix model - academia; consumer/society; government; and industry - to each region and country in light of this triple aim.

  • Entomopathogenic Fungi in Insects

    From Physiological Effects to Applications
    • 1st Edition
    • Arash Zibaee + 2 more
    • English
    Entomopathogenic Fungi in Insects: From Physiological Effects to Applications explores the complex relationships between entomopathogenic fungi and insects. This interdisciplinary book delves into the physiological, immunological, and behavioral responses elicited by fungi in insects, offering insights for sustainable development. It assesses the potential applications of these fungi as biopesticides against harmful insects while considering their impact on non-target populations. This comprehensive work is invaluable for researchers and professionals in agroecosystems, insect pathology, biocontrol, plant protection, and crop health, as well as graduate students focused on sustainability.In addition, the book examines the mutualistic roles fungi can play in insect physiology, such as aiding in digestion. These fungi, prevalent in insect habitats, can serve as microbial pest control agents by infecting and weakening insect hosts. The book emphasizes the importance of mitigating potential harm to non-target insect populations, ensuring a balanced approach to biocontrol in agricultural practices.

  • Advances in Parasitology

    • 1st Edition
    • Volume 129
    • English
    Unveiling the Proteolytic Networks of Parasites, Volume 129 in the Advances in Parasitology series, presents a cutting-edge exploration of specific proteases across a spectrum of parasitic organisms. Top researchers in the field conduct multifaceted examinations, shedding light on the distinct roles of these proteases within significant parasite groups, including malaria, trematodes, nematodes, and blood-feeding arthropods. Chapters in this new release include The roundworm Ascaris: recent advances and progress towards elimination, Genetically modified helminths as pharmaceutical bio-factories, Epithelial cytokines in helminth infections, Schistosoma eggs: from conception to eggs-creation, Helminth extracellular vesicles: roles in and beyond parasite-host communication, and more.

  • Vestibular Schwannomas

    • 1st Edition
    • Volume 212
    • English
    Vestibular Schwannomas covers multiple facets of vestibular schwannomas, including advancements in surgical techniques, radiological innovations, long-term patient outcomes, and implications for hearing preservation. It serves as a comprehensive guide for clinicians and researchers aiming to enhance diagnostic accuracy and therapeutic strategies in managing these complex tumors which are benign, slow-growing tumors that originate from the Schwann cells that line the vestibular nerve. They are the most prevalent neoplasms found in the cerebellopontine angle (CPA), the critical junction between the cerebellum and the brainstem.Their incidence, clinical presentation, and impact on surrounding neurological structures make them a focal point of research and medical intervention. Understanding their etiology, diagnosis, and treatment options requires an interdisciplinary approach bridging neurology, otology, and radiology.

  • Theranostics in Cancer Management

    Integrating Diagnostics and Therapeutic Strategies
    • 1st Edition
    • Kuttiappan Anitha + 2 more
    • English
    Theranostics in Cancer Management: Integrating Diagnostics and Therapeutic Strategies introduces a transformative paradigm in clinical oncology, heralding a new era of precision and personalized cancer care. This comprehensive guide empowers clinicians by seamlessly integrating advanced diagnostics with targeted therapeutic approaches. The book provides an extensive exploration of theranostics across diverse clinical scenarios, ensuring that healthcare professionals are equipped with the knowledge to navigate the complexities of cancer management effectively. Beyond the introductory insights, the book delves into several types of cancer and the utilization of Artificial Intelligence in cancer detection tools.Comprising 15 chapters, it offers an invaluable resource for health professionals, scientists, researchers, practitioners, and students who seek to expand their understanding in this evolving field. The emphasis on practical applications and emerging technologies makes it a timely addition to the field of oncology.

  • Climate Change and Disability

    A Collaborative Approach to a Sustainable Future
    • 1st Edition
    • Marcalee Alexander + 2 more
    • English
    Until recently, little attention has been paid to the concerns of people living with disabilities during extreme weather events and long-term climate changes. Climate Change and Disability: A Collaborative Approach to a Sustainable, Inclusive Future for All delineates the general and specific risks of climate change for people living with disabilities and how we can use accessible approaches to mitigate, adapt, and control these risks, while maximizing opportunities for people living with disabilities. The book opens with an introduction on how we got here. The book continues with sections on actions and research, the physiologic impact of different disabilities, and discussions of specific continents and countries, where issues related to climate change exist. Education and advocacy are covered in detail, and the book wraps up with a section on action and research, detailing how to respond to extreme weather events including how various types of disabilities are impacted by different events.Climate Change and Disability: A Collaborative Approach to a Sustainable, Inclusive Future for All serves as a guide for a broad audience at the crossroads of environmental adaptation and human health. Physicians, as well as nurses, physical and occupational therapists, and other allied health professionals will find it valuable for tailoring care for people living with disabilities due to climate change. Advocates and individuals living with disabilities will gain insight into advocacy for inclusive policies and personal preparedness. Scientists and clinicians interested in the health and societal impacts of climate change will find it useful in informing their research and practice. Policymakers and politicians can utilize this resource to develop equitable climate strategies, ensuring that environmental justice concerns are inclusive.

  • Advances in Immunology

    • 1st Edition
    • Volume 167
    • English
    Advances in Immunology, Volume 167, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Chapters in this new release include Recent Advances in Antifungal Immunity, Neuroimmunology beyond the CNS: nerve-macrophage interactions in peripheral tissues, Regulatory T cell functions in peripheral tissues, Alarmins in mucosal tissues and how they regulate health and disease, Ontogeny and function of microglia and nerve-associated macrophages, and Modulation of humoral immunity by γδ T cells.

  • AI Technologies for Crop Breeding

    • 1st Edition
    • Jen-Tsung Chen
    • English
    AI Technologies for Crop Breeding offers the latest insights into the use of artificial intelligence models to improve plant health and production. Presenting applications of AI technologies in plant biology, biotechnology, and crop breeding, it explores practices for the mitigation of biotic and abiotic stressors as well as other plant growth challenges.AI-based technologies are expected to advance approaches to plant functional genomics and multiple omics, resulting in smarter and more efficient crop breeding for next-generation agriculture helping to address the challenges of the increasing human population and the globally changing climate. AI tools such as machine learning, particularly deep learning, have been applied to predict chief players in complicated biological networks, increasing the understanding of in-depth mechanisms of plant-pathogen and plant-environment interactions. Additionally, responses of plants facing stress can be modeled using AI technologies, and the resulting data are valuable not only to plant stress physiology but also for stress-resilient and disease-resistant crop breeding.This book introduces AI technologies for studying plant biology, focusing on machine learning and deep learning models for integrating multiple omics approaches and revealing the knowledge of plant functional genomes. Technological advancements and emerging applications of machine learning and deep learning in genomic selection, genome-wide association study (GWAS), phenotyping and constructing phenomics, and transcriptomics are also featured in this book.AI Technologies for Crop Breeding is an ideal reference for researchers, academics, and advanced-level students and professors in the fields of plant sciences, plant stress physiology, bioinformatics, systems biology, and crop breeding.

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