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Elsevier

Books in Life sciences

  • Genomics-Guided Natural Products Discovery

    • 1st Edition
    • Volume 717
    • English
    Genomics-Guided Natural Products Discovery, Volume 717 focuses on how the genomics revolution has catalyzed a resurgence of interest in natural products research. With the explosion of new sequencing data to analyze, “genome-mining” tools have grown in sophistication. Hence, this volume captures the utility of these tools, serving as a how-to guide to lower the entry barrier for newcomers. Topics covered in this new release include Merging RODEO with genomic enzymology workflows to guide RiPP discovery, Exploring Ribosomally Synthesized and Post-translationally Modified Peptides through SPECO-Based Genome Mining, Genome Mining for Natural Products Made by Multinuclear Iron-dependent Oxidation Enzymes (MNIOs), and much more.Additional sections explore Genome-based discovery of polyketides generated by trans-acyltransferas... polyketide synthases, Global genome mining in fungi using FunBGCe, Plant genome mining of burpitides from fused precursor peptides, Determining biosynthetic gene cluster boundaries thru comparative bioinformatics, Genome mining for bacterial terpenoids, Bioinformatics guided synthesis of natural product cyclic peptides, Overview of Genome Mining Strategies for Natural Products Discovery, and much more.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 127
    • English
    Advances in Clinical Chemistry, Volume 127 explores physiologic and pathophysiologic biochemistry in both general and clinical chemistry. Complex molecular pathways are elucidated using historical, current, and emerging technologies such as biosensor design, metabolomics, and proteomics. Chapters in this new release include The Cancer Microbiome, Metabolomics of Nephrotic Syndrome, Advances in Biomimetic Sensor Technology, Gel electrophoresis-base... proteoform separation and analysis, Advances in blood microsampling technology for cancer biomarker detection, and MDDB: A public databank of host microRNAs in Tuberculosis diagnosis.

  • Management and Treatment of Cerebral Aneurysms, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 35-3
    • Daniel Sahlein + 1 more
    • English
    In this issue of Neuroimaging Clinics, guest editors Drs. Daniel Sahlein and Charles Kulwin bring their considerable expertise to the topic of Management and Treatment of Cerebral Aneurysms. Top experts discuss diagnostic and clinical aspects of cerebral aneurysms, as well as epidemiology, unruptured cerebral aneurysms, predicting cerebral aneurysm rupture, subarachnoid hemorrhage, and follow-up imaging in treated and untreated cerebral aneurysms.

  • Environmental Pollution and Cardiovascular Diseases

    • 1st Edition
    • Sultan Ayoub Meo
    • English
    Environmental Pollution and Cardiovascular Diseases helps stakeholders enhance their knowledge about environmental pollution, weather conditions, climate change, and impacts on the cardiovascular system. The book further aims to ameliorate the global burden of cardiovascular deaths attributable to pollution by identifying trends in pollution-linked cardiovascular disease from the 1990s to present day. Overall, air pollution is estimated to cause about 34% of ischemic heart disease deaths. As these figures show no sign of declining, this book is a must-have for researchers, cardiologists, and others seeking to understand such an important etiological factor in so many cardiovascular illnesses.

  • Cryo-electron Tomography

    A Journey From Sample Preparation to Data Mining
    • 1st Edition
    • Dorit Hanein + 1 more
    • English
    Cryo-Electron Tomography: A Journey from Sample Preparation to Data Mining providing a holistic overview of this rapidly advancing field and equipping researchers with the knowledge and tools necessary to initiate their own investigations. The book begins with a section on advanced cryogenic sample preparation for in situ cellular tomography, covering a range of sample types including viruses, bacteria, eukaryotic cells, and perspectives for organoids and tissues. Specific chapters focus on essential approaches such as vitrification, sample thinning, and bimodal correlative techniques. The book then transitions to a section on data mining and validation.

  • Autoimmune Hemolytic Anemias

    A Practical Guide
    • 1st Edition
    • Wilma Barcellini + 1 more
    • English
    Autoimmune Hemolytic Anemias: A Practical Guide is a comprehensive update of autoimmune hemolytic anemias, a rare disease that is sometimes difficult to diagnose and manage. This book describes diagnosis, pathogenesis, classification, standard therapy, new treatments, as well as secondary forms, such as lymphoproliferative, immunodeficiency, Evans, and other autoimmune diseases. It is a practical guide to manage transfusions and monitoring complications, such as infections and thromboses, and preventive measures. This book is useful to researchers, clinicians, doctors and students working in hematology, transfusion centers, immunohematology labs, and internal medicine.

  • Narcolepsy

    Integrating Basic and Clinical Knowledge
    • 1st Edition
    • Ahmed S. BaHammam + 2 more
    • English
    Narcolepsy: Integrating Basic and Clinical Knowledge provides comprehensive coverage of narcolepsy-related topics. The book offers updated, deep coverage of its diagnosis, treatment, and impact on mental health based on the latest research findings and clinical practices. Its interdisciplinary approach brings together experts from different specialties, such as sleep medicine, psychology, and neurology to offer a more holistic understanding. This allows for a more nuanced discussion of how narcolepsy interacts with various aspects of health and well-being. Researchers and clinicians will find within this book novel information on pathophysiology and neurobiology, as well as behavioral and psychosocial considerations.Users will find this to be a resource that takes a deep dive into narcolepsy, introducing topics never before discussed in books on the topic, including COVID-19 and sleep, as well as immunotherapy and gene therapy. It’s the cutting-edge medical volume professionals need, whether narcolepsy specialists or more casual readers.

  • Recent Advances in Liver Cirrhosis Related Complications

    • 1st Edition
    • Xingshun Qi + 1 more
    • English
    Recent Advances in Liver Cirrhosis Related Complications provides comprehensive coverage on the contemporary management of liver cirrhosis related complications and future directions for the field. Content covers epidemiology, diagnosis, risk stratification, and pathophysiology. Contents include coverage of the gut microbiota, ascites, and gastrointestinal bleeding as well as the challenges of hepatic encephalopathy, acute kidney injury, bacterial infections, coagulation abnormality, and venous thromboembolism, amongst others. This is the perfect resource for practicing gastroenterologists and hepatologists as well as family physicians and investigators who are skilled at the management of liver cirrhosis and its complications.

  • Handbook of Proteolytic Enzymes

    Metallopeptidases
    • 4th Edition
    • Neil D. Rawlings + 1 more
    • English
    Handbook of Proteolytic Enzymes, Metallopeptidases has stood as most comprehensive work in the field of applied enzymology and biocatalysis since the first edition published in 1998. Extensively revised and updated, the new fourth edition is an essential reference for biochemists, biotechnologists, and molecular biologists across academia and industry. Edited by world-renowned experts in the field, and with five volumes available for individual sale, this work provides detailed information on all known proteolytic enzymes researched to-date, with expanded coverage of metallopeptidases, cysteine peptidases, serine and threonine peptidases, aspartic and glutamic peptidases, and inhibitors of proteolytic enzymes.This volume includes over 300 chapters on known metallopeptidases enzymes, including their name, history, activity and specificity, structural chemistry, preparation, biological aspects, and distinguishing features, with 2D structures of peptidases in color, extensive references, and links to PubMed and MEROPS databases.

  • Advances in Biomembranes and Lipid Self-Assembly

    • 1st Edition
    • Volume 41
    • English
    Advances in Biomembranes and Lipid Self-Assembly, Volume 41 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

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