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Books in Life sciences

  • Biosimilars and Biologics in Cancer Treatment

    An Era in Therapeutic Strategies
    • 1st Edition
    • Kuttiappan Anitha + 2 more
    • English
    Biosimilars and Biologics in Cancer Therapy: An Era in Therapeutic Strategies addresses challenges and opportunities in biosimilars and biologics, integrating the latest evidence, regulatory landscapes, economic implications, and strategies to enhance cancer management. The book aims to create an all-inclusive educational resource, bridge the gap between research and clinical practice, and inspire future research in oncology. It provides a comprehensive examination of cancer therapeutics, starting with an introduction to biologics and biosimilars, their historical development, and foundational principles. Sections explain mechanisms of action, drug development processes, regulatory landscapes, and clinical applications through case studies. Emerging therapeutic strategies, including combination therapies and personalized medicine, are also covered. This book benefits researchers, oncologists, pharmacologists, pathologists, and other healthcare professionals by offering up-to-date insights into the clinical aspects of biological medications and their biosimilars. Contributions from global experts ensure readers gain the latest advancements and practical guidance on integrating these therapies into clinical practice and research.

  • Advanced Technologies for Disease Intervention

    Innovations Across Precision Medicine, Nutrition and Holistic Therapies
    • 1st Edition
    • Ranbir Chander Sobti + 3 more
    • English
    Advanced Technologies for Disease Intervention: Innovations Across Precision Medicine, Nutrition and Holistic Therapies, Two Volume Set investigates current and emerging advances in disease detection, diagnosis, treatment and prevention, and how molecular medicine and biotechnology have contributed to this changing landscape. Volume One focuses on sustainable health practices through biotechnology, exploring traditional health systems, diagnostic innovations, and integrative therapies. Key topics include: the role of traditional medicine and practices in sustainable health; contemporary and emerging technologies such as aptamer diagnostics, telemedicine, nanomaterials and AI in healthcare, and much more.Volume Two then delves deeper into emerging technologies for disease intervention, focusing on drug development, delivery systems, nutrition, and natural products for health. Themes explored here include: developments and trends in drug discovery; drug repurposing; contemporary drug delivery systems; phototherapeutics; personalized drug delivery; innovations in vaccine development; the role of nutraceuticals in disease prevention; and the use of natural products and herbal interventions for sustainable health.

  • The Handbook of Autobiographical Memory

    From Basic to Applied Perspectives
    • 1st Edition
    • Mohamad El Haj + 2 more
    • English
    The Handbook of Autobiographical Memory: From Basic to Applied Perspectives offers a comprehensive view on autobiographical memory from a multidisciplinary approach. The book explores contemporary advances in understanding both cognitive and neural processes, including historical contexts on autobiographical memory theory and assessment. The book further synthesizes insights from cognitive, developmental, and social aspects of autobiographical functioning while also covering departures from norms in terms of autobiographical memory dysfunction. A section on applications equips readers with essential information regarding the assessment and detection of autobiographical memory dysfunction in neurological and psychiatric populations. How such processes evolve over the lifespan, and how deviations from healthy memory function can be supported through novel rehabilitation practices are also covered.

  • Cardiopulmonary Interactions in Sleep

    Comprehensive Approaches to Mitral Regurgitation and Sleep-Disordered Breathing
    • 1st Edition
    • Kyriakos Dimitriadis + 1 more
    • English
    Cardiopulmonary Interactions in Sleep: Comprehensive Approaches to Mitral Regurgitation and Sleep-Disordered Breathing delves into the correlation between these two serious conditions. Commonly found in patients with cardiovascular disease and heart failure, the interplay between mitral regurgitation and sleep-disordered breathing creates a vicious cycle of clinical deterioration. Their coexistence not only exacerbates disease severity but also increases mortality and adverse cardiovascular outcomes. This book addresses a significant gap in research by exploring this connection and offering insights into diagnosis and treatment.In addition to covering the diagnosis of these conditions, the book discusses coexistent pathologies such as arrhythmias and heart failure. It is the first to focus on the effects of surgical and transcatheter techniques on sleep-disordered breathing. The positive impact of these interventions on sleep respiration and the resulting benefits for mitral valve repair are meticulously analyzed, making it a valuable resource for understanding and treating these interconnected conditions.

  • Molecular Insights for Harnessing Urine Biomarkers in Precision Medicine

    • 1st Edition
    • Cheng Xue + 3 more
    • English
    Molecular Insights for Harnessing Urine Biomarkers in Precision Medicine provides a comprehensive exploration into the molecular signatures and clinical implications of urine biomarkers, providing invaluable insights for clinicians, researchers, and healthcare professionals. From historical perspectives to cutting-edge technologies, this reference presents an updated understanding of urine biomarkers' role across diverse bodily systems. With sections devoted to fundamental concepts, molecular signatures, and clinical applications, readers gain a deep understanding of urine biomarkers' significance in disease diagnosis and personalized medicine.Each chapter explores specific body systems, including renal, urological, cardiovascular, and respiratory, uncovering the diagnostic potential of urine biomarkers in various conditions like cancer, cardiovascular diseases, and neurological disorders. Highlighted are the latest advances in technology, challenges, and future directions, keeping readers abreast of the rapidly evolving landscape of urine biomarker research. Real-world case studies illustrate practical applications, enhancing comprehension and facilitating knowledge transfer to clinical practice.

  • Apolipoprotein E in Health and Disease

    Unravelling its Intricate Roles
    • 1st Edition
    • Dileep Kumar + 2 more
    • English
    Apolipoprotein E in Health and Disease: Unravelling its Intricate Roles delves into the multifaceted functions of Apolipoprotein E (ApoE) across various health conditions and diseases. This comprehensive volume offers an in-depth exploration of ApoE, illuminating its structural insights, functional significance, and genetic variability. Each chapter examines the role of ApoE in different disease contexts, including cardiovascular diseases, Alzheimer's disease, neurological disorders, metabolic syndrome, liver health, cancer, and inflammatory disorders. Key chapters investigate ApoE's impact on lipid metabolism, atherosclerosis, and heart health while also probing its involvement in genetic predispositions and mechanistic implications in Alzheimer's disease. In addition, the book extends its exploration to the broader influence of ApoE on cognitive decline and other neurological conditions, metabolic health, liver function, cancer risk, and immune modulation. With a strong focus on the pharmacogenetics of ApoE, the book paves the way for precision medicine, offering insights into how ApoE genotypes influence medication responses and therapeutic strategies. Future prospects and challenges in harnessing ApoE for disease management are discussed, alongside its role in infectious diseases, genetic engineering innovations, and targeted drug delivery systems.

  • An Authoritative Guide to Chronic Pediatric Abdominal Pain

    Pathophysiology, Diagnosis and Management
    • 1st Edition
    • Miguel Saps + 1 more
    • English
    An Authoritative Guide to Chronic Pediatric Abdominal Pain: Pathophysiology, Diagnosis and Management provides a comprehensive and extensive overview of all aspects relevant to the care of children with abdominal pain. It includes chapters tailored to each discipline, level of training, and primary interest (clinical or research), covering daily practice, diagnosis, testing, conventional and complementary treatments, interdisciplinary care, and the transition to adult gastroenterology treatment. The book critically updates the evidence behind these methods and prepares readers to understand more advanced techniques. Topics include early adverse life events, intestinal permeability, visceral hypersensitivity, sex differences, microbiome infections, use of antibiotics, and the microbiome.Informati... on clinical perspectives and management in the emergency department helps inform pediatricians, gastroenterologists, residents, fellows, and nurse practitioners about the scientific basis for prior workups, differential diagnoses, and the rationale behind them. In addition, this book helps clinicians understand the basic research behind these factors, how they influence pathophysiology, clinical presentation, progression, and outcomes.

  • Marine Mercury Bioaccumulation

    • 1st Edition
    • Luiz Drude de Lacerda
    • English
    Marine Mercury Bioaccumulation presents state-of-the-art research on mercury bioaccumulation in marine life. Written by leading experts in marine toxicology, this book delivers the latest information on monitoring and modeling mercury biomagnification in key marine taxa. Early chapters introduce the basic biology and ecology of how mercury travels through marine organisms and accumulates within marine food webs. Central chapters discuss the current status and exposure risks of key taxa, including marine vegetation, invertebrates, fishes, mammals, and birds. The book concludes with an assessment of human exposure to mercury through seafood products and novel modeling tools to assess environmental exposure risks and bioaccumulation.User... will find this to be a great resource for a global assessment of mercury contamination in the ocean, including biological resources, monitoring and modeling, current tools, existing research gaps, and suggestions on how to improve our monitoring and policy tools for improved safety of marine life and human consumption. This is an indispensable tool for researchers, resource managers, fisheries stakeholders, and students alike.

  • Protein Kinase Inhibitors

    The Promise of Natural Products in Cancer Therapeutics
    • 1st Edition
    • Md. Imtaiyaz Hassan + 1 more
    • English
    Protein Kinase Inhibitors: The Promise of Natural Products in Cancer Therapeutics explores a novel therapeutic avenue for cancer treatment through nutraceutical-based kinase inhibitors. The book covers their historical background, outlook, mechanistic pathways, and clinical aspects, highlighting their relevance in cancer therapy. It also examines the potential of polyphenolic derivatives and other natural compounds in inhibiting key kinases involved in major cancer signaling pathways, focusing on their application in clinical trials and marketed drugs. Sections explore the implications of polyphenols in cancer management, novel sources of breast cancer inhibitors, the role of natural products in lymphoma therapy, and the multitarget potential of phytochemicals. Each chapter is designed to provide a thorough understanding of how natural products can be harnessed to develop innovative cancer therapeutics. It will serve as a valuable resource for academics, scientists, young researchers, students, and pharmacists working or interested in kinase biology and cancer therapeutics with its unique perspective on using nature's own arsenal to combat cancer.

  • The Fauna of Australia’s Tropical Savanna Biome

    Biodiversity, Biogeography, and Conservation
    • 1st Edition
    • Alan Andersen + 1 more
    • English
    The Fauna of Australia's Tropical Savanna Biome: Biodiversity, Biogeography and Conservation considers the full range of vegetation types and freshwater systems that occur within the dominant savanna matrix in Australia's monsoonal tropics. Edited by renowned experts of tropical ecology, it provides descriptions of diversity, taxonomic, functional composition and endemism, and ecological and biogeographical questions of wide interest. Chapters explore how diversity and composition vary among different habitats in a savanna landscape and along the savanna rainfall gradient. The book also considers how distinctive savanna fauna is within Australia and compared with tropical savannas elsewhere in the world. The book considers the unique biogeographic and evolutionary history of this highly diverse and distinctive biome, building on a rich foundation of knowledge accrued over decades of research on many aspects of the region's biodiversity, conservation values, and challenges. This is an indispensable resource for students and researchers studying tropical biodiversity, as well as conservationists and land managers of Australia's tropical savanna biome and those found across the globe.

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