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Books in Life sciences

  • The Handbook of Autobiographical Memory

    From Basic to Applied Perspectives
    • 1st Edition
    • Mohamad El Haj + 2 more
    • English
    The Handbook of Autobiographical Memory: From Basic to Applied Perspectives offers a comprehensive view on autobiographical memory from a multidisciplinary approach. The book explores contemporary advances in understanding both cognitive and neural processes, including historical contexts on autobiographical memory theory and assessment. The book further synthesizes insights from cognitive, developmental, and social aspects of autobiographical functioning while also covering departures from norms in terms of autobiographical memory dysfunction. A section on applications equips readers with essential information regarding the assessment and detection of autobiographical memory dysfunction in neurological and psychiatric populations. How such processes evolve over the lifespan, and how deviations from healthy memory function can be supported through novel rehabilitation practices are also covered.

  • Cardiopulmonary Interactions in Sleep

    Comprehensive Approaches to Mitral Regurgitation and Sleep-Disordered Breathing
    • 1st Edition
    • Kyriakos Dimitriadis + 1 more
    • English
    Cardiopulmonary Interactions in Sleep: Comprehensive Approaches to Mitral Regurgitation and Sleep-Disordered Breathing delves into the correlation between these two serious conditions. Commonly found in patients with cardiovascular disease and heart failure, the interplay between mitral regurgitation and sleep-disordered breathing creates a vicious cycle of clinical deterioration. Their coexistence not only exacerbates disease severity but also increases mortality and adverse cardiovascular outcomes. This book addresses a significant gap in research by exploring this connection and offering insights into diagnosis and treatment.In addition to covering the diagnosis of these conditions, the book discusses coexistent pathologies such as arrhythmias and heart failure. It is the first to focus on the effects of surgical and transcatheter techniques on sleep-disordered breathing. The positive impact of these interventions on sleep respiration and the resulting benefits for mitral valve repair are meticulously analyzed, making it a valuable resource for understanding and treating these interconnected conditions.

  • Molecular Insights for Harnessing Urine Biomarkers in Precision Medicine

    • 1st Edition
    • Cheng Xue + 3 more
    • English
    Molecular Insights for Harnessing Urine Biomarkers in Precision Medicine provides a comprehensive exploration into the molecular signatures and clinical implications of urine biomarkers, providing invaluable insights for clinicians, researchers, and healthcare professionals. From historical perspectives to cutting-edge technologies, this reference presents an updated understanding of urine biomarkers' role across diverse bodily systems. With sections devoted to fundamental concepts, molecular signatures, and clinical applications, readers gain a deep understanding of urine biomarkers' significance in disease diagnosis and personalized medicine.Each chapter explores specific body systems, including renal, urological, cardiovascular, and respiratory, uncovering the diagnostic potential of urine biomarkers in various conditions like cancer, cardiovascular diseases, and neurological disorders. Highlighted are the latest advances in technology, challenges, and future directions, keeping readers abreast of the rapidly evolving landscape of urine biomarker research. Real-world case studies illustrate practical applications, enhancing comprehension and facilitating knowledge transfer to clinical practice.

  • Apolipoprotein E in Health and Disease

    Unravelling its Intricate Roles
    • 1st Edition
    • Dileep Kumar + 2 more
    • English
    Apolipoprotein E in Health and Disease: Unravelling its Intricate Roles delves into the multifaceted functions of Apolipoprotein E (ApoE) across various health conditions and diseases. This comprehensive volume offers an in-depth exploration of ApoE, illuminating its structural insights, functional significance, and genetic variability. Each chapter examines the role of ApoE in different disease contexts, including cardiovascular diseases, Alzheimer's disease, neurological disorders, metabolic syndrome, liver health, cancer, and inflammatory disorders. Key chapters investigate ApoE's impact on lipid metabolism, atherosclerosis, and heart health while also probing its involvement in genetic predispositions and mechanistic implications in Alzheimer's disease. In addition, the book extends its exploration to the broader influence of ApoE on cognitive decline and other neurological conditions, metabolic health, liver function, cancer risk, and immune modulation. With a strong focus on the pharmacogenetics of ApoE, the book paves the way for precision medicine, offering insights into how ApoE genotypes influence medication responses and therapeutic strategies. Future prospects and challenges in harnessing ApoE for disease management are discussed, alongside its role in infectious diseases, genetic engineering innovations, and targeted drug delivery systems.

  • An Authoritative Guide to Chronic Pediatric Abdominal Pain

    Pathophysiology, Diagnosis and Management
    • 1st Edition
    • Miguel Saps + 1 more
    • English
    An Authoritative Guide to Chronic Pediatric Abdominal Pain: Pathophysiology, Diagnosis and Management provides a comprehensive and extensive overview of all aspects relevant to the care of children with abdominal pain. It includes chapters tailored to each discipline, level of training, and primary interest (clinical or research), covering daily practice, diagnosis, testing, conventional and complementary treatments, interdisciplinary care, and the transition to adult gastroenterology treatment. The book critically updates the evidence behind these methods and prepares readers to understand more advanced techniques. Topics include early adverse life events, intestinal permeability, visceral hypersensitivity, sex differences, microbiome infections, use of antibiotics, and the microbiome.Informati... on clinical perspectives and management in the emergency department helps inform pediatricians, gastroenterologists, residents, fellows, and nurse practitioners about the scientific basis for prior workups, differential diagnoses, and the rationale behind them. In addition, this book helps clinicians understand the basic research behind these factors, how they influence pathophysiology, clinical presentation, progression, and outcomes.

  • Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics

    • 1st Edition
    • Lara Scheherazade Milane + 1 more
    • English
    Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics delves into the complex world of intercellular communication biology and its implications on therapeutics. This book covers all areas of intercellular communication and therapeutics in development for different forms of communication, including their role in diseases such as cancer, neurological disorders, metabolic diseases, and inflammatory/immune diseases. Sections provide an introduction, biological targets, challenges, and approaches to overcoming biological barriers and the significance of contact points and mechanisms of internalization. Specifics of tunneling nanotubes, extracellular vesicles, and the immune and non-immune interface in various diseases are covered. Furthermore, the book explores the crosstalk of different forms of intercellular communication and the implications of mitochondrial exchange in the four primary pathological areas. This is an essential resource for researchers, students, and professionals in the field of drug development and delivery. By connecting the dots between extracellular vesicles, tunneling nanotubes, and cell-cell junctions, this book serves as a foundation for further advancements in the science of intercellular communication and it's applications to new drug discovery and delivery.

  • Marine Mercury Bioaccumulation

    • 1st Edition
    • Luiz Drude de Lacerda
    • English
    Marine Mercury Bioaccumulation presents state-of-the-art research on mercury bioaccumulation in marine life. Written by leading experts in marine toxicology, this book delivers the latest information on monitoring and modeling mercury biomagnification in key marine taxa. Early chapters introduce the basic biology and ecology of how mercury travels through marine organisms and accumulates within marine food webs. Central chapters discuss the current status and exposure risks of key taxa, including marine vegetation, invertebrates, fishes, mammals, and birds. The book concludes with an assessment of human exposure to mercury through seafood products and novel modeling tools to assess environmental exposure risks and bioaccumulation.User... will find this to be a great resource for a global assessment of mercury contamination in the ocean, including biological resources, monitoring and modeling, current tools, existing research gaps, and suggestions on how to improve our monitoring and policy tools for improved safety of marine life and human consumption. This is an indispensable tool for researchers, resource managers, fisheries stakeholders, and students alike.

  • Protein Kinase Inhibitors

    The Promise of Natural Products in Cancer Therapeutics
    • 1st Edition
    • Md. Imtaiyaz Hassan + 1 more
    • English
    Protein Kinase Inhibitors: The Promise of Natural Products in Cancer Therapeutics explores a novel therapeutic avenue for cancer treatment through nutraceutical-based kinase inhibitors. The book covers their historical background, outlook, mechanistic pathways, and clinical aspects, highlighting their relevance in cancer therapy. It also examines the potential of polyphenolic derivatives and other natural compounds in inhibiting key kinases involved in major cancer signaling pathways, focusing on their application in clinical trials and marketed drugs. Sections explore the implications of polyphenols in cancer management, novel sources of breast cancer inhibitors, the role of natural products in lymphoma therapy, and the multitarget potential of phytochemicals. Each chapter is designed to provide a thorough understanding of how natural products can be harnessed to develop innovative cancer therapeutics. It will serve as a valuable resource for academics, scientists, young researchers, students, and pharmacists working or interested in kinase biology and cancer therapeutics with its unique perspective on using nature's own arsenal to combat cancer.

  • The Fauna of Australia’s Tropical Savanna Biome

    Biodiversity, Biogeography, and Conservation
    • 1st Edition
    • Alan Andersen + 1 more
    • English
    The Fauna of Australia's Tropical Savanna Biome: Biodiversity, Biogeography and Conservation considers the full range of vegetation types and freshwater systems that occur within the dominant savanna matrix in Australia's monsoonal tropics. Edited by renowned experts of tropical ecology, it provides descriptions of diversity, taxonomic, functional composition and endemism, and ecological and biogeographical questions of wide interest. Chapters explore how diversity and composition vary among different habitats in a savanna landscape and along the savanna rainfall gradient. The book also considers how distinctive savanna fauna is within Australia and compared with tropical savannas elsewhere in the world. The book considers the unique biogeographic and evolutionary history of this highly diverse and distinctive biome, building on a rich foundation of knowledge accrued over decades of research on many aspects of the region's biodiversity, conservation values, and challenges. This is an indispensable resource for students and researchers studying tropical biodiversity, as well as conservationists and land managers of Australia's tropical savanna biome and those found across the globe.

  • A Comprehensive Guide to Dorsal Root Ganglion Stimulation for Pain Management

    • 1st Edition
    • Scott G. Pritzlaff + 4 more
    • English
    A Comprehensive Guide to Dorsal Root Ganglion Stimulation for Pain Management explores the theoretical foundations, clinical applications, and technical nuances of DRG stimulation, providing a robust framework for understanding and implementing this advanced pain management technique. The book consolidates current best practices, novel technical considerations, and emerging research into a single, authoritative volume. Main themes include the anatomical and physiological basis of DRG stimulation, clinical indications, patient selection, surgical techniques, device programming, and long-term patient outcomes. By integrating insights from leading experts in the field, the book provides a comprehensive and practical guide for clinicians, researchers, and students. Distinct from existing titles that merely touch upon the subject, this book offers a detailed and specialized focus on DRG stimulation, including up-to-date evidence, clinical guidelines, and case studies. The book also features pedagogical elements such as learning objectives, review questions, and case studies to enhance understanding and application.

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