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Elsevier

Books in Life sciences

  • Drug Design

    Medicinal Chemistry: A Series of Monographs, Vol. 8
    • 1st Edition
    • E. J. Ariëns
    • English
    Drug Design, Volume VIII covers a critical review and new extensions of quantitative methods in drug design, the design of particular types of agents, such as synthetic sweeteners, and selective ion binding compounds. The book discusses the advances in the methodology of quantitative drug design; the application of pattern recognition to drug design; and the design of controlled drug delivery systems. The text also describes the use of receptor binding as a tool in the development of new bioactive steroids; the design of synthetic sweeteners; and the prospective assessment of environmental effects of chemicals. The design of selective ion binding macrocyclic compounds and their biological applications are also encompassed. Chemists, pharmacologists, biochemists, and people involved in drug design and manufacture will find the book invaluable.

  • Contributions to Contemporary Neurology

    A Tribute to Joseph Michael Foley
    • 1st Edition
    • Robert B. Daroff + 1 more
    • English
    Contributions to Contemporary Neurology features articles presented at the scientific meeting at the March 1986 gala evening affair held in Cleveland, Ohio in honor of neurologist Joseph Michael Foley's seventieth birthday and his impending transition to Professor Emeritus at Case Western University. This book is organized into 20 chapters written by 41 contributors. It starts with the biography of Foley and ends with his curriculum vitae. In between the biographies and curriculum vitae are basic and clinical articles written by professionals closely associated with Foley throughout his illustrious career. This book will be of interest to those interested in learning about the life and career of neurologist Joseph Michael Foley.

  • Surtsey

    Evolution of Life on a Volcanic Island
    • 1st Edition
    • Sturla Fridriksson
    • English
    Surtsey: Evolution of Life on a Volcanic Island focuses on the origin of life in the island of Surtsey. The book first offers information on the Surtsey Research Society, conservation measures, and scientists that comprise the Surtsey research team. The text then focuses on the submarine eruptions off the coasts of Iceland, the flow of lava, and the formation and disappearance of islets. The book also describes the landscape that came about after the eruption. The tephra cones of the Surtur I and II craters, lava, coastal plains, and thermal areas are discussed. The text also underscores the ecological aspects of the eruption. The Icelandic biota and ecological studies on the island are discussed. The text also traces the origin of life in the island, including the dispersal of seeds by birds and “Mermaids purses.“ The text also underscores the origin of marine algae and marine fauna on the island. The book then emphasizes the presence of bacteria, molds, lichens, mosses, terrestrial animals, birds, and vascular plants in the island. The text also examines the outer Westman Islands. Topographical features, method of research, plant communities, and vegetation of the smaller islands are described. The book also notes the vegetation of Heimaey and the effects of insular eruptions on the southern coast of Iceland. The text is a good source of reference for readers wanting to study volcanic eruptions.

  • The Exergy Method of Thermal Plant Analysis

    • 1st Edition
    • T. J. Kotas
    • English
    The Exergy Method of Thermal Plant Analysis aims to discuss the history, related concepts, applications, and development of the Exergy Method - analysis technique that uses the Second Law of Thermodynamics as the basis of evaluation of thermodynamic loss. The book, after an introduction to thermodynamics and its related concepts, covers concepts related to exergy, such as physical and chemical exergy, exergy concepts for a control method and a closed-system analysis, the exergy analysis of simple processes, and the thermocentric applications of exergy. A seven-part appendix is also included. Appendices A-D covers miscellaneous information on exergy, and Appendix E features charts of thermodynamic properties. Appendix F is a glossary of terms, and Appendix G contains the list of references. The text is recommended for physicists who would like to know more about the Exergy Method, its underlying principles, and its applications not only in thermal plant analysis but also in certain areas.

  • Infectious Diseases

    • 2nd Edition
    • A. Melvin Ramsay + 1 more
    • English
    Infectious Diseases, Second Edition furnishes the basic facts regarding the common infections encountered in the British Isles. The infectious diseases covered in this edition include varicella and herpes zoster, smallpox, tetanus, measles, mumps, influenza, and acute respiratory disease. The poliomyelitis, Stevens-Johnson syndrome, malaria, tuberculosis, cytomegalic inclusion disease, and rabies are also discussed. This book likewise deliberates the host-parasite relationship, control of infection in hospitals, sterilization and disinfection, pyrexia of undetermined origin (PUO), and public health law. This publication is valuable not only to clinicians but also to epidemiologists, microbiologists and community physicians whose work is connected with the many problems in the field of acute medicine.

  • Drug Design

    Medicinal Chemistry: A Series of Monographs, Vol. 6
    • 1st Edition
    • E. J. Ariëns
    • English
    Drug Design, Volume VI covers practical approaches to the development of bioactive compounds, with focus on antiradiation agents, organ-imaging radiopharmaceuticals... X-ray contrast media, proteinase inhibitors, and pesticide formulations. The book discusses the chemical routes available for the synthesis of diphenhydramine derivatives, the biological activities, the relationships between structure and activity, and the phase of manipulation in the design of diphenhydramine derivatives. The text also describes the design of antiradiation agents, organ-imaging radiopharmaceuticals... and X-ray contrast media, as well as the rational approach to proteinase inhibitors. The chemical and physical methods of formulation of agricultural pesticides are also encompassed. Chemists, biochemists, pharmacologists, and people involved in drug design and manufacture will find the book invaluable.

  • Thyroid Disease and Muscle Dysfunction

    • 1st Edition
    • Ian Ramsay
    • English
    Thyroid Disease and Muscle Dysfunction covers the pioneering work of the author in the study of muscle dysfunction in patients with thyrotoxicosis. His contributions on this subject represent real advances in the understanding of metabolic muscle disease. This book is written to clarify the association between abnormalities of skeletal muscle and derangement of thyroid function. This book is organized into five chapters that describe the muscular abnormalities in people with hypothyroidism, explain the concepts of thyrotoxic periodic paralysis and thyrotoxic myopathy, discuss the association between thyroid disease and myasthenia gravis, and describe the changes in thyroid functions associated with miscellaneous muscle disorders. This book will be of interest to persons dealing with studies on the relation between thyroid disease and muscle dysfunction.

  • The Nervous System

    Autonomic Nervous System Drugs
    • 1st Edition
    • Walter S. Root + 1 more
    • English
    Physiological Pharmacology: A Comprehensive Treatise, Volume III: The Nervous System — Part C: Autonomic Nervous System Drugs focuses on the effects of drugs on the nervous system, including cardiovascular effects and metabolism. The selection first offers information on the cardiovascular effects of choline esters and the effects of choline esters on smooth muscles and secretions. Topics include actions of acetylcholine, physiological role of choline esters, and actions of cholinergic drugs on smooth muscles and secretions. The book also takes a look at the pharmacologic, toxicologic, and therapeutic properties of anticholinesterase agents, including the chemistry and metabolism of anticholinesterase substances and mechanisms of action of anticholinesterase agents and role of cholinesterases. The publication examines muscarinic blocking drugs and ganglion-blocking drugs. Discussions focus on actions on the secretory glands and cardiovascular system; distribution, metabolism, and excretion of atropine; substances that block ganglionic transmission; and cardiovascular effects. The text also elaborates on neuromuscular blocking drugs. The selection is a dependable reference for readers interested in the effects of drugs on the nervous system.

  • Trophic Regulation of the Basal Ganglia

    Focus on Dopamine Neurons
    • 1st Edition
    • K. Fuxe + 2 more
    • English
    Trophic Regulation of the Basal Ganglia: Focus on Dopamine Neurons examines neurotransmitters. The book first discusses the role of fibroblast growth factor-2 (FGF-2) and ganglioside GM1 and the trophic regulation of the basal ganglia. Biochemical and histochemical studies on the cellular localization of FGF-2; mapping of FGF-2 and its receptors in the basal ganglia postnatally and adulthood; and mapping of the ganglioside GM1 distribution in the basal ganglia are presented. The text also explains glucocorticoid and estrogen effects on the nigrostriatal and mesolimbic dopaminergic systems; factors associated to dopaminergic cell death in Parkinson's disease; and compensatory mechanisms at dopamine D-2 receptors. The book also describes the effects of brain-derived neurotrophic factor on injured dopaminergic neurons; role of gangliosides and trophic factors in brain repair; and features of the trophic action of polyamines. The text also underscores the presence of interleukin-1 in the central nervous system; neuropeptides synthesis in astrocytes; and astrocytic kynurenines as modulators of dopaminergic function in the rat basal ganglia. The selection is a good source of information for readers wanting to study neurotransmitters.

  • Recent Advances in Animal Nutrition

    • 1st Edition
    • P. C. Garnsworthy + 2 more
    • English
    Recent Advances in Animal Nutrition: 1992 is an annual review of the changes and updates in the field of animal nutrition, especially progresses in the study of feeds. The book is divided into four parts. Part I discusses topics related to nutrition in non-ruminant animals, while Part II covers ruminant nutrition. Part III tackles studies about general nutrition such as the use of growth promoters in animal feeds and predicting the response to variation and diet, and Part IV deals with feed compounding and its effects. The text is recommended for agriculturists, zoologists, and those involved in the development and manufacture of feeds who would like to know more about the nutrition of agriculturally important animals.

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