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Books in Life sciences

  • Proteomic and Metabolomic Approaches to Biomarker Discovery

    • 1st Edition
    • Haleem J. Issaq
    • English
    Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. Various techniques are used in the biomarker discovery process, including techniques used in proteomics, the study of the proteins that make up an organism, and metabolomics, the study of chemical fingerprints created from cellular processes. Proteomic and Metabolomic Approaches to Biomarker Discovery is the only publication that covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods, and presents a standard operating procedure for sample selection, preparation, and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. A vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals, and graduate students, Proteomic and Metabolomic Approaches to Biomarker Discovery provides the information needed to reduce clinical error in the execution of research.

  • Bioenergetics

    • 4th Edition
    • David G. Nicholls
    • English
    Extensively revised, the fourth edition of this highly successful book takes into account the many newly determined protein structures that provide molecular insight into chemiosmotic energy transduction, as well as reviewing the explosive advances in 'mitochondrial physiology'-the role of the mitochondria in the life and death of the cell. Covering mitochondria, bacteria and chloroplasts, the fourth edition of Bioenergetics provides a clear and comprehensive account of the chemiosmotic theory and its many applications. The figures have been carefully designed to be memorable and to convey the key functional and mechanistic information. Written for students and researchers alike, Bioenergetics is the most well-known, current and respected text on chemiosmotic theory and membrane bioenergetics available.

  • The Future of Drug Discovery

    Who Decides Which Diseases to Treat?
    • 1st Edition
    • Tamas Bartfai + 1 more
    • English
    The Future of Drug Discovery: Who decides which diseases to treat? provides a timely and detailed look at the efforts of the pharmaceutical industry and how they relate, or should relate, to societal needs. The authors posit that as a result of increasing risk aversion and accelerated savings in research and development, the industry is not developing drugs for increasingly prevalent diseases, such as Alzheimer’s disease, untreatable pain, antibiotics and more. This book carefully exposes the gap between the medicines and therapies we need and the current business path. By analyzing the situation and discussing prospects for the next decade, the The Future of Drug Discovery is a timely book for all those who care about the development needs for drugs for disease.

  • Physiological Systems in Insects

    • 3rd Edition
    • Marc J. Klowden
    • English
    Physiological Systems in Insects discusses the roles of molecular biology, neuroendocrinology, biochemistry, and genetics in our understanding of insects. All chapters in the new edition are updated, with major revisions to those covering swiftly evolving areas like endocrine, developmental, behavioral, and nervous systems. The new edition includes the latest details from the literature on hormone receptors, behavioral genetics, insect genomics, neural integration, and much more. Organized according to insect physiological functions, this book is fully updated with the latest and foundational research that has influenced understanding of the patterns and processes of insects and is a valuable addition to the collection of any researcher or student working with insects. There are about 10 quintillion insects in the world divided into more than one million known species, and some scientists believe there may be more than 30 million species. As the largest living group on earth, insects can provide us with insight into adaptation, evolution, and survival. The internationally respected third edition of Marc Klowden's standard reference for entomologists and researchers and textbook for insect physiology courses provides the most comprehensive analysis of the systems that make insects important contributors to our environment.

  • Persistent Organic Pollutants and Toxic Metals in Foods

    • 1st Edition
    • Martin Rose + 1 more
    • English
    Persistent organic pollutants (POPs) and toxic elements, such as dioxins, flame retardants, lead and mercury, are substances of major concern for the food industry, the regulator and the public. They persist in the environment, accumulate in food chains and may adversely affect human health if ingested over certain levels or with prolonged exposure. Persistent organic pollutants and toxic metals in foods explores the scientific and regulatory challenges of ensuring that our food is safe to eat.Part one provides an overview of regulatory efforts to screen, monitor and control persistent organic pollutants and heavy metals in foods and includes case studies detailing regulatory responses to food contamination incidents. Part two moves on to highlight particular POPs, toxic metals and metalloids in foods, including dioxins and polychlorinated biphenyls (PCBs), mercury, polycyclic aromatic hydrocarbons (PAHs) and phthalates.Persisten... organic pollutants and toxic metals in foods is a standard reference for those in the food industry responsible for food safety, laboratories testing for food chemical safety, regulatory authorities responsible for ensuring the safety of food, and researchers in industry and academia interested in the science supporting food chemical safety.

  • Advances in Immunology

    • 1st Edition
    • Volume 118
    • Frederick W. Alt
    • English
    Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.

  • The Psychology of Learning and Motivation

    • 1st Edition
    • Volume 59
    • English
    Psychology of Learning and Motivation publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving. Each chapter thoughtfully integrates the writings of leading contributors, who present and discuss significant bodies of research relevant to their discipline. Volume 59 includes chapters on such varied topics as pupillometric studies of face memory, self-organization of human interaction, and the role of relational competition in the comprehension of modifier-noun phrases and noun-noun compounds.

  • The Biology and Identification of the Coccidia (Apicomplexa) of Rabbits of the World

    • 1st Edition
    • Donald W. Duszynski + 1 more
    • English
    The Biology and Identification of the Coccidia (Apicomplexa) of Rabbits of the World is a taxonomic summation of a damaging intestinal parasite found in rabbits and transmissible to other species, including humans. This book conceptually and historically summarizes the world's literature on the parasite and also provides a quick guide to isolation procedures, identification, strategies for management, and available chemotherapy. It is a vital source of knowledge about coccidia’s real and potential transmission to humans, which can lead to dangerous health problems, like severe dehydration, vomiting, lethargy and even death. Coccidiosis is an intestinal disease that affects several different animal species, including canines and humans, and is one of the most prevalent protozoal infections in North America. The causative agent is a protozoan that has the ability to multiply rapidly and cause major damage in the intestinal wall, rupturing the cells of the intestinal lining. The final stage, the oocyst, is extremely resistant to environmental stress and is difficult to completely remove from the environment. Oocysts are frequent contaminants of feed and water and when the sporulated oocysts are ingested by other animals, they start the life cycle over in the new host. With the demand for rabbits in scientific research and for rabbit meat for human consumption increasingly globally each year, rabbits are of epidemiologic significance for laboratory workers, university researchers, veterinarians, pet owners, and breeders.

  • Transfusion Medicine and Hemostasis

    Clinical and Laboratory Aspects
    • 2nd Edition
    • Beth H. Shaz + 1 more
    • English
    The second edition of Transfusion Medicine and Hemostasis continues to be the only "pocket-size" quick reference for pathology residents and transfusion medicine fellows. It covers all topics in blood banking, transfusion medicine, and clinical and laboratory based coagulation. Short, focused chapters, organized by multiple hierarchical headings, are supplemented with up to 10 suggested reading citations. This single reference covers essentially all the topics required to meet the goals and objectives of a major program in transfusion medicine and clinical coagulation. New chapters in the coagulation testing section reflect the development of new tests available and their incorporation into clinical practice. Coverage includes essential updates on the importance of new cellular therapies, peripheral blood and bone marrow hematopoietic progenitor cells, as well as cord blood banking and regenerative medicine. The authors also examine advances in the understanding of molecular testing and pathogen reduction in two separate quality control chapters (one for blood centers and one for hospitals).

  • Advances in Planar Lipid Bilayers and Liposomes

    A Tribute to Marin D. Mitov
    • 1st Edition
    • Volume 17
    • English
    Advances in Planar Lipid Bilayers and Liposomes volumes cover a broad range of topics, including main arrangements of the reconstituted system, namely planar lipid bilayers as well as spherical liposomes. The invited authors present the latest results of their own research groups in this exciting multidisciplinary field.

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