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Academic Press

  • Coronary Physiology in the Cardiac Cath Lab

    • 1st book:metaData.edition
    • William F. Fearon
    • publicationLanguages:en
    Coronary Physiology in the Cardiac Cath Lab provides the foundational knowledge required to understand the concepts behind a variety of coronary physiologic assessments performed and required to apply them effectively when evaluating cardiac patients. Written to bring a practical and evidence-based approach, this book is a valuable resource for interventional and general cardiologists, cardiology researchers, physicians, cardiac catheterization laboratory staff, and anyone interested in understanding the theory and current practice surrounding assessing coronary physiology in the cardiac cath lab.Over the past decade, there has been an explosion of data validating the importance of assessing coronary physiology at the time of coronary angiography. This has led to the development of numerous new techniques and metrics for performing these assessments and also resulted in the inclusion of these indices into practice guidelines.

  • Conceptual Breakthroughs in Comparative Animal Physiology

    • 1st book:metaData.edition
    • James Hicks contributors.plusContributors
    • publicationLanguages:en
    Conceptual Breakthroughs in Comparative Animal Physiology tells a story of innate human curiosity about the natural world, and a deeply creative discipline, shaped by varied environments, unusual organisms, elegant experiments, and the persistent effort to understand how animals work and why they work the way they do; and along the way discovery of “adaptations and mechanisms of the most surprising character”.Written by two leading experts in the field, each chapter reflects on the origins of ideas and the approach of turning natural diversity into experimental design. From deserts to oceans, from the anoxia-tolerant animals to endothermic insects, from deep-diving mammals to the integration of ‘omics’; each chapter follows the discoveries and people who were compelled to modify their view of "what life can do". The chapters also highlight the long-term influence of key conceptual breakthroughs, demonstrating how insights from comparative physiology have shaped not only the field itself but also, ecology, evolution, and engineering. As scientists strive to understand the complexity of, the book underscores the inherit integrative nature of, revealing a process that strives to connects genes to organisms and organisms to environments, and providing a framework understanding the diversity of life. This is an essential resource for undergraduates, graduate students and researchers interested in physiology with its comprehensive synopsis on the field’s foundational history and significant advances.

  • The AI Frontier in Molecular Modelling and Drug Designing

    • 1st book:metaData.edition
    • Manish Kumar Gupta contributors.plusContributors
    • publicationLanguages:en
    The AI Frontier in Molecular Modelling and Drug Designing aims to provide a comprehensive guide on the application of AI concepts in drug designing, discovery, and molecular modeling. The book delves into machine and deep learning techniques that predict structural properties of molecules, identify druggable pockets, and assess physicochemical properties of targets. Sections explore current and potential computational resources to tackle complex biological challenges. Each chapter is enriched with relevant examples, text boxes, and case studies that illustrate the practical application of AI techniques, their outcomes, and the challenges faced during implementation.This resource is tailored for researchers, students, and professionals in both academia and industry, providing them with the latest methodologies, advancements in technology, and practical insights into AI-driven drug research, structural biology, computational biology, and translational science.

  • Patient Treatment and Management Following an Osteoporotic Vertebral Compression Fracture

    • 1st book:metaData.edition
    • Douglas P. Beall
    • publicationLanguages:en
    Worldwide, vertebral compression fractures (VCFs) continue to be the most common major fragility fracture, affecting patients over the age of 50, and osteoporosis is the most prevalent condition associated with VCFs. Patient Treatment and Management Following an Osteoporotic Vertebral Compression Fracture provides treatment and management guidance of the osteoporosis disease process in patients who have had a VCF. This book opens with a foundation of osteoporosis and VCF and then reviews clinical and radiological assessment approaches, evaluation, treatment, and ongoing management options. Subsequent chapters cover the efficacy of the different vertebral augmentation types on patient outcomes, optimization methods, decisions for osteoporosis treatment in these patients, and recommendations to improve patient outcomes. Special attention is paid to the treatment sequence and objectives following an osteoporotic VCF. This book concludes with coverage of insightful developments in clinical management and current research and features targeted case studies representing common patient characteristics that showcase varying aspects of different VCFs and the underlying osteoporosis that gives rise to these fractures. This title serves as an invaluable resource for any practitioner managing fragility fractures in older patients as well as treating their underlying osteoporosis.

  • RNases in Health and Diseases

    From Housekeeping Enzymes to Moonlight Proteins
    • 1st book:metaData.edition
    • Ester Boix
    • publicationLanguages:en
    RNases in Health and Diseases: From Housekeeping Enzymes to Moonlight Proteins provides coverage of the structural and functional properties of RNases, introducing new concepts such as their recently discovered multifaceted properties, their involvement in the generation of non-coding signaling RNAs, and their proposed uses as diagnostic and therapeutic tools. This book's sections cover the structure of RNases, present research methods and tools to study RNases, and delve into RNases and diseases. Users will find a wider perspective on the topics discussed that will serve researchers and students engaged in the study of RNases who are interested in acquiring a better understanding.

  • Metabolomic Phenotyping for the Future of Personalized Medicine

    Beyond the Biomarkers
    • 1st book:metaData.edition
    • Jacopo Troisi contributors.plusContributors
    • publicationLanguages:en
    Metabolomic Phenotyping for the Future of Personalized Medicine: Beyond the Biomarkers takes a critical look at the advancements in the field. It begins by explaining the essential steps of metabolomics analysis—from sample collection to data interpretation—while exploring how these workflows pave the way for targeted medical applications. With a focus on precision, it shows how metabolomics provides key insights into the mechanisms behind diverse phenotypes, making it an indispensable asset for biomedical research. The second section dives into the transformative results achieved in major medical domains through metabolomics, detailing how this emerging science contributes to understanding complex disease mechanisms.The book also outlines the international regulatory framework essential for conducting research within this field, ensuring compliance and ethical standards. By combining practical guidelines with visionary insights, this text serves as a cornerstone for future strides in personalized medicine and highlights the growing influence of metabolomics in shaping tomorrow’s healthcare systems.

  • Recent Advances in Molecular Docking

    Methods, Tools, and Applications
    • 1st book:metaData.edition
    • Khalid Raza
    • publicationLanguages:en
    Recent Advances in Molecular Docking: Methods, Tools, and Applications offers an authoritative guide to modern molecular docking techniques, emphasizing the integration of artificial intelligence and machine learning. The volume covers foundational principles, computational workflows, and advanced scoring functions, providing researchers and practitioners with practical tools to improve drug-target interaction predictions. It highlights applications across pharmaceuticals, including cancer, neurological disorders, and infectious diseases, which are all supported by real-world case studies. Challenges in docking accuracy, reproducibility, validation, and ethical and regulatory considerations are also covered.Authored by international experts, it bridges theoretical knowledge with practical applications, making it an essential resource for computational biologists, pharmacologists, and drug developers aiming to leverage AI-driven docking in precision medicine.

  • Physical Principles of Imaging in Medicine

    • 1st book:metaData.edition
    • Adam W. Anderson contributors.plusContributors
    • publicationLanguages:en
    Medical Imaging: Mathematical and Physical Principles gives an introduction to the mathematical and physical concepts and principles that underlie modern radiological imaging techniques. It explains the basic phenomena and mathematical concepts that are central to the use of physical methods for image formation in biomedicine. By focusing on the physical and mathematical principles, it provides knowledge that will continue to hold true even as technological and other advances change the nature and detail of future medical imaging applications.Written as a pedagogic textbook explaining the principles rather than a technical manual describing imaging methods, Medical Imaging: Mathematical and Physical Principles is very suitable as a foundational reference for senior undergraduates, graduate students and researchers with a background in either biomedical engineering, engineering, applied physics, computer science, and mathematics. It will be a well-thumbed resource throughout a researcher’s career.

  • AI and Blockchain for Wireless Communications

    Creating Resilient and Secure Systems
    • 1st book:metaData.edition
    • Ferheen Ayaz contributors.plusContributors
    • publicationLanguages:en
    AI and Blockchain for Wireless Communications: Creating Resilient and Secure Systems describes the merger of AI and blockchain for the smooth functioning of secure wireless communications. The book covers both sides of blockchain and AI integration – blockchain for assisting AI, such as solutions involving distributed learning and trustworthy AI, and AI solutions designed to support blockchain, such as solutions embedded in smart contracts for automation and authentication. The methods and techniques presented in the book are also supported by use cases that show the practical implementation of AI and blockchain based wireless communication systems. It is suitable for students, researchers, and industry engineers in AI, blockchain, and wireless communications, and will help AI developers grasp concepts and see the benefits of blockchain integrated with AI—particularly in wireless communications—thus setting the groundwork for their future development.

  • Building Blocks of Neuroimmunometabolism

    From Molecular Pathways to Therapeutic Strategies
    • 1st book:metaData.edition
    • Sachchida Nand Rai contributors.plusContributors
    • publicationLanguages:en
    Building Blocks of Neuroimmunometabolis... From Molecular Pathways to Therapeutic Strategies offers an authoritative exploration of the intricate relationship between the immune system and neurodegenerative diseases. This essential resource addresses the critical gap in understanding how immune responses and metabolic processes jointly influence the onset and progression of conditions such as Alzheimer’s, Parkinson’s, and multiple sclerosis. The book provides a comprehensive examination of key molecular pathways and cellular interactions, emphasizing the role of immunometabolism in disease mechanisms.Beginning with an introduction to the concept of immunometabolism, the book explores the connections between the immune and nervous systems, setting the stage for understanding neurodegenerative diseases. It discusses pivotal topics such as the role of microglia and macrophages in neuroinflammation, the metabolic regulation of T cells, and the impact of oxidative stress and mitochondrial dysfunction. The gut-brain axis is examined for its influence on brain health, alongside innovative therapeutic strategies targeting immunometabolic pathways and lifestyle interventions.Buildi... Blocks of Neuroimmunometabolis... From Molecular Pathways to Therapeutic Strategies is invaluable for researchers, clinicians, and students seeking to understand the complex interactions driving neurodegeneration. The book offers cutting-edge insights into immunometabolism, highlighting its potential to revolutionize therapeutic strategies and improve patient outcomes in neurodegenerative disorders.

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