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Academic Press

  • γδ T Cells in Health and Disease Part B

    • 1st Edition
    • Volume 398
    • English
    γδ T Cells in Health and Disease, Part B provides a comprehensive and up-to-date overview of the diverse roles that γδ T cells play in human physiology and pathology. This volume builds on foundational knowledge to explore advanced topics and recent discoveries in γδ T cell biology, with a particular focus on their mechanisms of action, functional diversity, and implications for clinical practice. Chapters in this new release cover Development of gd T cells, Human T-cell receptor inborn errors of immunity shed light on the real-life role of γδ vs αβ T lymphocytes, and much more.Other sections explore Deciphering the Role of γδ T cells in Skin Inflammatory Diseases: Insights from Psoriasis, Atopic Dermatitis, and Alopecia Areata, Role of gd T cells in zoonosis infection, γδ T cells in Escherichia coli infection and Gamma-delta T cells in breast cancer: dual role in tumor immunity and emerging therapeutic approaches.

  • Synthetic Biology and its Consequences in Present Healthcare

    • 1st Edition
    • Bhupendra G. Prajapati + 3 more
    • English
    Synthetic Biology enables the capability to manipulate and modify leaving cells and organisms to program them for specific purposes and has the potential to change the course of the healthcare sector. Synthetic Biology and its Consequences in Present Healthcare presents the latest findings and applications those in the healthcare sector need. Chapters cover a variety of synthetic biological tools in lifestyle diseases like obesity, heart disease, liver disease, type 2 diabetes and more. In addition, the vaccine development will cover DNA vaccines, synthetic and modified RNA-based vaccines, and personal vaccines for cancer, thus filling a gap in literature in the synthetic biology space. Written by international experts in the fields for those researching, practicing or studying in life sciences, biological sciences, including the synthetic biology domain.

  • Asian Horseshoe Crabs

    Biology, Ecology, Conservation, and Utilization
    • 1st Edition
    • Menghong Hu + 1 more
    • English
    Asian Horseshoe Crabs: Biology, Ecology, Conservation, and Utilization provides a comprehensive and updated look at horseshoe crabs, often dubbed “living fossils.” Overfishing and environmental pressures have endangered these crustaceans, making this book essential for their protection. Authored by international experts, it focuses on three species: Tachypleus tridentatus, Tachypleus gigas, and Carcinoscorpius rotundicauda, covering their evolution, reproduction, physiology, and behaviors. Moreover, the book delves into the genomics and population dynamics of horseshoe crabs, examining their significance in human consumption and biomedical research, and including the use of blue blood and chitin.Conservation efforts and practices are also discussed, making this book a valuable resource for marine biologists, students, and academics.

  • Investigative and Predictive DNA Testing

    • 1st Edition
    • Hirak Ranjan Dash
    • English
    Investigative and Predictive DNA Testing delves into the cutting-edge of DNA analysis, presenting a comprehensive guide that unlocks the potential of DNA in solving complex cases. This book stands as a vital resource for students, practitioners, and researchers in fields such as biology, zoology, medicine, anthropology, microbiology, and genetics. Designed for those with a basic understanding of biological sciences, it is particularly beneficial for graduate, post-graduate, and research level students. The book explores the evolution of DNA analysis, focusing on predictive methods and investigative leads such as ancestry, lineage, and phenotype.Each chapter, contributed by internationally renowned experts, highlights the transformative role of artificial intelligence and machine learning in enhancing the accuracy and utility of DNA analysis. The book is comprised of various sections, starting with fundamental concepts of investigative and predictive DNA analysis, followed by technological advancements in the field, and concluding with the challenges and future concerns of DNA analysis. It serves as an indispensable tool for anyone looking to expand their knowledge and skills in DNA analysis, making it a must-read for the scientific community.

  • Advances in Management of Pediatric Brain Tumors

    • 1st Edition
    • Volume 167
    • English
    Advances in Management of Pediatric Brain Tumors, Volume 167 encapsulates the latest developments in the field for various types of pediatric brain tumors. By examining these survival gaps, the volume offers insights into strategies for improving outcomes and bridging the gap in care on a global scale. Chapters in this new release include Pediatric-type diffuse low grade gliomak, Pediatric-type diffuse high grade glioma/Diffuse Midline glioma, Ependymoma, Choroid plexus tumors, Embryonal tumors/medulloblasto... Craniopharyngioma and other sellar-region tumors, and much more.Other sections cover Germ cell tumors, Immunotherapy for pediatric brain tumors, Emerging interventional treatments in the management of pediatric brain tumors, and Management of pediatric brain tumors in low-middle income countries.

  • Extracellular Mitochondria in Health and Disease

    • 1st Edition
    • Carla Lopes + 1 more
    • English
    Extracellular Mitochondria in Health and Disease covers this new and significant area of research, shedding light on their roles in intercellular communication and disease pathology. These tiny powerhouses, traditionally known for their intracellular functions, are now recognized for their extracellular activities that impact various physiological and pathological processes. The book delves into a range of topics, including cellular mechanisms of mitochondrial transfer, metabolic signaling, and the crosstalk between extracellular vesicles and mitochondria. It serves as a comprehensive guide for scientists, researchers, and students eager to explore these novel findings and their potential implications.Other sections examine the roles of extracellular mitochondria in immune regulation and inflammation, neurodegeneration and neuroprotection, and their therapeutic potential. By bridging gaps in existing literature, this resource offers up-to-date research and discoveries, providing valuable insights into how extracellular mitochondria could revolutionize medical advancements and improve patient outcomes.

  • NanoPDT

    Nanomaterials-Enhanced Photodynamic Therapy
    • 1st Edition
    • Saeid Moghassemi + 2 more
    • English
    NanoPDT: Nanomaterials-Enhanc... Photodynamic Therapy covers extensively the therapeutic potential of multifunctional nanosystems that has made so much progress within the biomedical and pharmaceutical research communities over recent decades. Traditional photodynamic therapy (PDT), however, faces several limitations, primarily due to the hydrophobic nature of photosensitizers (PS), which tend to aggregate in aqueous environments, resulting in inadequate biodistribution and limited bioavailability. These constraints significantly reduce the efficacy of photodynamic therapy. The book also explores the most relevant combination therapies available. Four chapters are dedicated to the combination of NanoPDT with other approaches like Immunotherapy, Radiotherapy, chemotherapy, and photothermal therapy. NanoPDT: Nanomaterials-Enhanc... Photodynamic Therapy is an essential resource for pharmaceutical researchers, clinicians, and students in the fields of nanomedicine, oncology, and photodynamic therapy. It offers a thorough exploration of the latest advancements and future directions, providing valuable insights for those looking to enhance the efficacy and specificity of PDT through nanotechnology and its combined applications. The book's comprehensive coverage of both oncological and non-oncological applications makes it a crucial addition to the literature, bridging the gap between fundamental research and clinical practice.

  • Leveraging Viruses for the Treatment of Viral Diseases and Cancer

    Improving Host Fitness Through Virus-Host Genetic Combinations
    • 1st Edition
    • Tibor Bakacs
    • English
    Leveraging Viruses for the Treatment of Viral Diseases and Cancer: Improving Host Fitness by Combinations of Virus and Host Genes gives a comprehensive overview on the impact of using naturally or intentionally attenuated viruses - which are apathogenic to people - to control viral diseases and cancer. It examines the potential of exploiting, developing, and using apathogenic viruses as therapeutic tools. Sections cover the COVID-19 pandemic and the need for a post-Infection Plan B to combat SARS-CoV-2 infections as gaps in testing and vaccination create the perfect conditions for a new variant of concern to emerge.More generally, the book also provides specific examples of the use of apathogenic viruses to treat other infectious diseases. It discusses the process of manufacturing viral therapies and how infectious disease treatments can be repurposed to improve other therapies like for cancer. With contribution from an international group of contributors, Leveraging Viruses for the Treatment of Viral Diseases and Cancer is useful references for those engages in study and development of infectious diseases and ways to combat them.

  • Oceanic Dolphins

    Ridgway and Harrison's Handbook of Marine Mammals, Volume 2
    • 1st Edition
    • Thomas Allen Jefferson
    • National Marine Mammal Foundation
    • English
    Oceanic Dolphins: Ridgway and Harrison's Handbook of Marine Mammals, Volume Two in the Handbook of Marine Mammals series, focuses on dolphins, the remarkable marine mammals that live in our seas and oceans. For centuries, dolphins have fascinated humans with their intelligence and adaptability. As our understanding of marine mammals expands, there is a growing need for comprehensive references on their ecology and biology. This series, created to meet this need, provides definitive reviews of all living species of whales, dolphins, porpoises, seals, sea lions, sea cows, and marine otters and bears.This volume features chapters written by leading global experts on offshore and oceanic dolphin species. Each chapter includes detailed descriptions of the species, covering aspects such as distribution and abundance, anatomy, physiology, behavior, ecology, reproduction, parasites and diseases, and the effects of human activities on these species.

  • Advances in Ecological Research

    • 1st Edition
    • Volume 73
    • English
    Advances in Ecological Research, Volume 73 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Sections in this new release cover A conceptual framework for pollination studies: an opinion paper, Bee diversity and crop pollination in low-diversity regions: Balancing global insights and local contexts, Regional Innovation Ecosystems to support sustainable forest landscape futures, and Evaluating the net impacts of a naturalized non-native species and attempts to control its spread in the UK: Addressing the oyster in the room.

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