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Academic Press

  • Handbook of Endocannabinoid Function in the Central Nervous System

    • 1st Edition
    • Volume 33
    • Olivier J. Manzoni + 1 more
    • English
    Handbook of Endocannabinoid Function in the Central Nervous System, a new release in the Handbook of Behavioral Neuroscience series, offers a comprehensive, interdisciplinary approach to understanding the role of the endocannabinoid system in functions of the central nervous system. This new volume brings together the most influential and internally recognized experts in the field to provide a detailed overview of the physiological and pathophysiological roles of endocannabinoids in CNS activity. It covers the history, functional anatomy, and neurophysiology of the endocannabinoid system, moving on to assess endocannabinoid roles across human lifespans, and in behavioral control.Final sections of the book explore the use of endocannabinoids in psychiatric and neurological disorders. This is a vital resource for neuroscientists, neuropharmacologists... and neuropathologists, as well as any researcher seeking detailed discussions of brain endocannabinoid functions.

  • Genome Analysis

    Principles and Methods
    • 1st Edition
    • Dev Bukhsh Singh + 1 more
    • English
    Genome Analysis: Principles and Methods provides recent and advanced information about genome analysis approaches and techniques to study and annotate the structure and function of the genome. It is a compendium of important topics such as NGS analysis, genome fragmentation and assembly, metagenomics, cloning and expression, physical marker analysis, transcriptome data analysis, sequence alignment and comparison, evolutionary analysis, SNP analysis, genome-based disease diagnosis and therapies, micro-RNAs, pharmacogenomics, genetic approaches to disease intervention, and challenges with opportunities in genome analysis and genomics, etc.The latest developments in the field are discussed, and key concepts are introduced to ensure readers understand advanced concepts and methodologies in the area. The book serves as a valuable guide to the present, emerging, and evolving research methodologies in the field.

  • International Review Research in Developmental Disabilities

    • 1st Edition
    • Volume 69
    • English
    International Review of Research in Developmental Disabilities series volume 69, highlights new advances in the field, with this new volume with this new volume presenting interesting chapters on topics such as Randomized Clinical Trials, Exploring Early Childhood and more.Additional chapters cover The Meaning of Family Advocacy in Diverse Cultural Landscapes and Practicing Partnership: Preparing Pre-Service Special Educators for Meaningful IEP Facilitation Through Simulation.

  • Lateral Flow Assays

    From Bench to Market
    • 1st Edition
    • Sibel Ayşıl Özkan + 1 more
    • English
    Lateral Flow Assays: From Bench to Market provides a detailed understanding of lateral flow assays (LFAs), the technology behind them, and their potential uses. The book opens with a discussion of the key elements of LFAs before covering a range of different LFA types, including aptamer-based and SERS-based LFAs. Applications across the biosciences and beyond are explored, such as virus detection, including Covid-19, bacteria detection, hormonal detection, and cancer biomarkers. LFAs for the detection of narcotics, environmental pollutants, food additives, allergens, toxins, and metabolites are also explored. The book then discusses commercialization aspects of LFAs before looking to future developments.This book offers a complete overview of these biosensors and is an ideal reference for researchers and lab technicians across the biomedical sciences who work with these devices. It is also relevant to researchers and practitioners in food chemistry, the environmental industry, and pharmaceutical companies, in addition to those involved in the development of lateral flow devices.

  • Transketolases

    • 1st Edition
    • Volume 722
    • English
    Transketolase is an ubiquitous enzyme which has not yet finished revealing all its secrets. This Methods in Enzymology: Transketolases volume is devoted to the description of cutting-edge methods to its study in biochemistry. Several topics are addressed by world experts in their field.The first part of this volume deals with transketolase at the cellular level. The latest scientific progress on human transketolase TKL1 in relation to certain diseases and to its inhibition are discussed including the involvement of this enzyme in new metabolic pathways or as a diagnostic biomarker.The second part focuses on transketolase at the molecular level. The structural and mechanistic aspects linked to this enzyme are addressed using several approaches including molecular modelling and crystallography, for example. Finally, the experimental methodological approaches relating to the use of transketolase as a tool of choice in biocatalysis is presented.

  • Machine Learning in Drug Development: Part 2

    • 1st Edition
    • Volume 65
    • English
    Machine Learning in Drug Development: Part Two, Volume 65 in the Annual Reports on Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this volume explore Transforming Modern Drug Discovery with Machine Learning – Applications in Ligand-based Drug Design, Optimizing Multi-Modal Drug Design Through Computational Pocket Mapping and Data Integration, Harnessing AI for Nucleic Acid Drug Discovery: Small Molecule Targeting DNA and RNA, AI-aided Drug Development for Protein Degraders: Design, Lead Identification, and Optimization, and more.Additional section delve into Artificial Intelligence in the Development of Antiviral Drugs – Progress and Applications, Artificial Intelligence for Drug Target Identification, and Machine Learning in Proteomic Biomarker Discovery

  • Genetic and Reproductive Approaches for Sustainable Livestock Production

    • 1st Edition
    • Sukanta Mondal
    • English
    Though global food demand is ever-increasing, agricultural productivity is declining, largely due to the shrinking of resources like cultivable land. Under such circumstances, the role of the livestock sector to fulfill growing food demand is particularly important for food and nutritional security. Genetic and Reproductive Approaches for Sustainable Livestock Production details the roles of both established and emerging reproductive and genomic technologies in creating more sustainable livestock production. This book outlines a variety of integrated strategies, covering traditional and modern omics approaches (structural, functional, comparative and epigenomics) and genomics-assisted breeding methods. These can be adopted and utilized to dissect and decode the gene regulatory networks involved in the quantitative yield and stress tolerance traits in livestock. Genetic and Reproductive Approaches for Sustainable Livestock Production is a particularly attractive resource for scientists, researchers, educators and professionals in livestock science, veterinary medicine, and food security. The work will allow professional readers to incorporate existing research into their practices and will prompt academics to build on existing research and make new discoveries.

  • Nanofiber Therapeutics

    Revolutionizing Cancer and Inflammation Management
    • 1st Edition
    • Neeraj Mishra + 2 more
    • English
    Nanofiber Therapeutics: Revolutionizing Cancer and Inflammation Management is a comprehensive resource designed to enrich knowledge, catalyze scientific advancements, empower patients, and inform policy decisions in nanomedicine. This book leverages the transformative potential of nanotechnology to combat cancer and inflammation, two of the most challenging health conditions today. The book explores the revolutionary potential of nanofiber-based therapeutics, aiming to develop innovative solutions that overcome existing treatment limitations and improve patient outcomes. It bridges the gap between basic scientific research and clinical application, synthesizing the latest advancements in nanofiber technology with insights from preclinical and clinical studies. Covering every facet of nanofiber therapies—from design and production to clinical applications—the book offers a comprehensive overview. It aims to educate healthcare professionals, researchers, policymakers, patients, and the public about the potential of nanofiber therapeutics, empowering stakeholders with the knowledge needed for informed decision-making and interdisciplinary collaboration. By highlighting cutting-edge research and technological innovations, this book inspires scientific curiosity and further research in the field. It fills a gap in the existing literature, laying the groundwork for future research and development, and driving advancements that could transform cancer and inflammation treatment.

  • Intelligent Systems for Neurocognition and Human-Robot-Computer Interaction

    • 1st Edition
    • Shubham Mahajan + 2 more
    • English
    Intelligent Systems for Neurocognition and Human-Robot-Computer Interaction explores the transformative potential of intelligent systems in enhancing human well-being through advancements in neurocognitive technologies, robotics, and AI-driven healthcare. This book addresses the fragmented knowledge at the intersection of these fields, enabling readers to understand the latest advancements and discover practical strategies for implementation. It highlights the importance of ethical considerations and governance in deploying AI and robotics in healthcare settings. Each chapter covers various aspects, including personalized medicine, human-robot interaction, cognitive robotics, wearable technologies, and the role of AI in mental health. The book also discusses the implications of cloud computing, big data, and human-computer interaction in enhancing cognitive and emotional well-being.

  • Hyponatremia and 40 Years of Controversy

    Looking Back and Moving Forward
    • 1st Edition
    • Richard H. Sterns
    • English
    Hyponatremia and 40 Years of Controversy: Looking Back and Moving Forward traces and probes the prolonged, contentious debate surrounding the treatment of severe hyponatremia, a low-sodium concentration in the blood that can result in severe brain damage if managed incorrectly.A mix of memoir and science, the book explains how slow correction of hyponatremia became accepted and how consensus was disrupted by assertions that caution was unnecessary and harmful. It scrutinizes the controversy, offers an approach to management, and unpacks research limitations – reminding us that what is believed true today may change tomorrow.Hyponatremi... and 40 Years of Controversy: Looking Back and Moving Forward is a vital resource for both experienced medical specialists and novice trainees. It explains the physiology of how hyponatremia happens and how it hurts. By offering historical insights, scientific rigor, and practical guidance, this book promises to enhance clinical decision making, foster new research, and improve outcomes in patients with hyponatremia.

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